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Human health and medicine

25,729 articles

Juvenile primary lateral sclerosis

Juvenile primary lateral sclerosis (JPLS, OMIM 606353) is a very rare autosomal recessive motor neuron disease caused by ALS2 mutations, beginning in childhood with progressive spasticity, loss of walking, and loss of speech.

Juvenile psoriatic arthritis

Juvenile psoriatic arthritis (JPsA) is a subtype of juvenile idiopathic arthritis in which chronic arthritis beginning before age 16 occurs together with psoriasis, dactylitis, or nail changes.

Juvenile temporal arteritis

Juvenile temporal arteritis (JTA), non-giant cell granulomatous temporal arteritis with eosinophilia, is a rare benign vasculitis of the superficial temporal arteries in people under about 45, presenting as temporal nodules without systemic symptoms, first described by Lie et al. in 1975.

Juvenile xanthogranuloma

Juvenile xanthogranuloma (JXG), the most common non-Langerhans cell histiocytosis, a benign self-regressing reddish-yellow skin nodule of infancy; systemic forms involve eye, CNS, liver, lung.

Juxtaglomerular apparatus

Juxtaglomerular apparatus (JGA), kidney structure at the glomerular vascular pole: granular renin-secreting cells, macula densa (~20 cells), and extraglomerular mesangium; mediates tubuloglomerular feedback and renin release via baroreceptor, macula densa, and sympathetic mechanisms.

Juxtaposition of the atrial appendages

Juxtaposition of the atrial appendages (JAA) is a rare congenital cardiac anomaly in which both atrial appendages lie on the same side of the great arteries, usually left-sided, typically associated with cyanotic defects such as transposition and tricuspid atresia.

Juyuan Decoction

举元煎 (Juyuan Decoction), a five-herb classical Chinese formula from Zhang Jiebin's Jingyue Quanshu (Ming dynasty), tonifies qi and lifts the sunken origin; listed in the Ancient Classic Famous Formulas Catalog (Second Batch), used mainly for gynecological bleeding.

Jvaraghni gutika

Jvaraghni gutika (ज्वरघ्नी गुटिका), also spelled Jwaraghni or Jwarghani Gutika, is a classical Ayurvedic pill (gutika/vati) formulation for fever (jvara). Recorded recipes include a mercury-sulphur-colocynth pill and a realgar-kutki-red ochre-ginger preparation; it is CGHS-listed.

Jvarankusa Rasa (jvaramkusa rasa)

Jvarāṅkuśa rasā (ka), AFI000450, is an Ayurvedic herbo-mineral fever formulation (125 mg dose) containing purified mercury, sulphur, orpiment, borax, ginger, Datura metel, Tinospora sinensis, and Eclipta prostrata, indicated for vishama jvara.

Jvararyabhra rasa

Jvararyabhra rasa (Jwarari Abhra Ras), a classical Ayurvedic herbo-mineral fever formula from Bhaishajyaratnavali with mercury, sulphur, mica and copper bhasmas, aconite and datura; AFI dose 125–250 mg.

JYB1904 (RPT904)

JYB1904 (RPT904, ozureprubart) is a half-life extended anti-IgE humanized monoclonal antibody developed by China's Jemincare and licensed to RAPT Therapeutics in December 2024 for food allergy, CSU, and asthma development outside Greater China.

Jyotismati Taila

Jyotismati Taila (Jyotiṣmatī Taila), an API Part II Vol III Ayurvedic medicated oil of Celastrus paniculatus processed with Achyranthes aspera kshara, used externally for leucoderma (Shvitraroga).

K-CADASIL study

K-CADASIL (NCT07497867) is a 10-year, multicenter prospective observational cohort of about 500 Korean CADASIL patients led by Jeju National University Hospital, tracking stroke, dementia, MRI small vessel disease burden, and NOTCH3 genetics from 2023 to 2040.

K-hole

K-hole (k-hole): slang for the intense dissociative state from high-dose ketamine, involving detachment from body and time, hallucinations, and temporary paralysis; achieved above roughly 150 mg or by injection, with risks of cystitis and dependence.

K-wire fixation

K-wire fixation is an orthopedic technique in which thin Kirschner wires are drilled through bone to hold fractures in alignment while they heal, mainly in the hand.

K. Craig Kent

K. Craig Kent is an American vascular surgeon who led UVA Health as CEO until resigning in February 2025 and was elected to the National Academy of Medicine in 2019.

Kabanos

Kabanos (kabanosy): thin Polish dry pork sausage, smoked and dried, eaten cold as a snack; EU TSG-registered since 2011 with fixed composition limits (protein ≥15%, fat ≤35%).

Kabasura Kudineer

Kabasura Kudineer (KSK), a polyherbal Siddha decoction from Tamil Nadu for febrile respiratory illness; trialed by CCRS for mild to moderate COVID-19 and distributed nationwide by India's Ministry of Ayush in 2021.

Kabuki syndrome

Kabuki syndrome (Niikawa–Kuroki syndrome), a rare congenital histone-modification disorder caused by KMT2D or KDM6A variants, with distinctive facies, fetal fingertip pads, growth and developmental delay, and emerging targeted therapies.

Kacciradi cirna

Kacciradi cirna (Kachuradi churna) is a classical Ayurvedic herbal powder for external application to the head, from the Sahasrayoga, with 18 equal-part ingredients led by Curcuma zedoaria, used for migraine, scalp burning, insomnia, and giddiness.

Kaccuradi Curna (kacciradi curna)

Kaccuradi Curna (Kaccūrādi cūrṇa, Kachuradi churna, Karcūrādi cūrṇa) is an Ayurvedic herbal powder led by Curcuma zedoaria rhizome, applied on the head with breast milk, castor oil, or butter for headache, fever, rhinitis, and eye or ear disorders; distinct AFI entries AFI000295 and AFI000734 exist.

Kaccuradi curna (kaccuradi cura)

Kaccūrādi cūrṇa (Kaccuradi Curna), Ayurvedic Formulary of India Part I 11:2, AFI000295; a ~30-ingredient herbal-mineral powder led by zedoary (Curcuma zedoaria), applied on the head with breast milk, castor oil, or butter for headache, rhinitis, fever, hiccup, and eye and ear disorders.

Kadali Ksara

Kadali Ksara (Kadalī kṣāra), an Ayurvedic alkaline preparation from banana plant ash (Musa paradisiaca), AFI formulation AFI000246, dose 125–250 mg, used in Amlapitta, urinary disorders, and Kshara karma procedures.

Kadambini Ganguly (কাদম্বিনী বসু গাঙ্গুলি)

Kadambini Ganguly, née Basu (1861–1923), was an Indian physician and social reformer, the first Indian woman to practice Western medicine and one of British India's first two female graduates in 1883.

KAEPacity study

KAEPacity study (NCT07440329): observational, mixed-methods document analysis of German hospital emergency and disaster plans (KAEP), 319 hospitals, led by Lea Kölsch with University Hospital Heidelberg, started March 2026, no clinical interventions.

Kagami-Ogata syndrome

Kagami-Ogata syndrome (KOS, KOS14, OMIM 608149) is a rare 14q32.2 imprinting disorder from deficient maternal RTL1as expression, causing bell-shaped thorax, coat-hanger ribs, polyhydramnios, and developmental delay; mirror of Temple syndrome.

Kaiser Permanente

Kaiser Permanente, also called KP, is an Oakland, California-based integrated managed care consortium founded in 1945 by Sidney Garfield and Henry J. Kaiser, serving about 12.4 million members through nonprofit health plan, hospitals, and Permanente Medical Groups.

Kaisora Guggulu

Kaisora Guggulu (Kaiśora guggulu), a classical Ayurvedic tablet of purified Commiphora wightii resin, triphala, Tinospora, and spices; AFI dose 3 g; used mainly for gout (Vatarakta), constipation, and skin diseases.

Kaixin San

Kaixin San (开心散) is a classical Chinese herbal formula of ginseng, polygala, poria, and Acorus, recorded in 652 for forgetfulness and now studied for depression and Alzheimer's disease.

Kakolyadi Cirna

Kakolyadi Cirna (Kakolyadi Churna): powdered Ayurvedic preparation of the Kakolyadi gana, an 18-drug group from Sushruta Samhita overlapping the Ashtavarga; sweet, cooling, Vatapittahara, dosed 3–6 g with milk or honey, used in wound pastes, poultices, and Chyavanaprasha.