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Human health and medicine

25,729 articles

Lymphoid polyp

Lymphoid polyp (lymphoid hyperplasia, benign lymphoma): a benign polyp of well-differentiated lymphoid tissue, typically in the terminal ileum or rectum, self-limiting and often mimicking carcinoid or lymphoma.

Lymphoma

Lymphoma, also called Hodgkin and non-Hodgkin lymphoma, is cancer of lymphocytes in the lymph system; Hodgkin is marked by Reed-Sternberg cells and is highly curable, while NHL spans indolent to aggressive subtypes with about 89,070 new US cases in 2025.

Lymphomatoid granulomatosis

Lymphomatoid granulomatosis (LYG) is a rare EBV-driven B-cell lymphoproliferative disease of the lungs, skin, CNS, and kidneys, graded 1 to 3 by EBV-positive B cells, treated with interferon or DA-EPOCH-R.

Lymphomatoid papulosis

Lymphomatoid papulosis (LyP), a primary cutaneous CD30+ lymphoproliferative disorder, is a chronic, self-healing recurrent papulonodular skin eruption with near-100% five-year survival but a 15–40% risk of associated lymphoma.

Lymphoplasmacytic lymphoma

Lymphoplasmacytic lymphoma (LPL), also called Waldenström macroglobulinemia when IgM-producing, is a rare indolent B-cell non-Hodgkin lymphoma of bone marrow, defined by MYD88 L265P in about 90% of cases and CD5/CD10-negative immunophenotype.

Lymphoproliferative disorders

Lymphoproliferative disorders (LPDs): excessive growth of lymphatic system cells, often EBV-driven, ranging from reactive to malignant; includes post-transplant PTLD, immunodeficiency-associated, and cutaneous LPDs.

Lymphoscintigraphy

Lymphoscintigraphy is a nuclear medicine imaging method that tracks radiolabeled particles through lymphatic vessels and nodes, used to diagnose lymphedema and guide sentinel lymph node biopsy in breast cancer and melanoma.

Lymphovenous anastomosis

Lymphovenous anastomosis (LVA, lymphovenous bypass, LVB) is a supermicrosurgical operation connecting lymphatic vessels to small veins to drain lymph around blockages, treating early-stage lymphedema and, done immediately at lymph node dissection, preventing secondary lymphedema.

Lynestrenol

Lynestrenol, also spelled lynoestrenol, is a synthetic steroidal progestogen developed by Organon that acts as a prodrug of norethisterone and is used in contraceptives and gynecology.

Lynn P. Carmichael

Lynn P. Carmichael (1929–2009) was an American family physician at the University of Miami who built the first family medicine residency program in the United States.

Lysholm knee score

The Lysholm knee score is an eight-item questionnaire rating symptoms and function after knee ligament injury, introduced by Jack Lysholm and Jan Gillquist in 1982.

Lysinuric protein intolerance

Lysinuric protein intolerance (LPI, hyperdibasic aminoaciduria, OMIM 222700) is an autosomal recessive SLC7A7 transporter defect causing lysine, arginine, and ornithine loss, urea cycle dysfunction, and lung, kidney, and immune complications.

Lysosomal acid lipase deficiency

Lysosomal acid lipase deficiency (LAL-D), formerly split into Wolman disease and cholesteryl ester storage disease, is an autosomal recessive LIPA-gene disorder causing lipid buildup, liver disease, and dyslipidemia, treated with sebelipase alfa.

Lysosomal storage disease

Lysosomal storage diseases (LSDs, lysosomal storage disorders): over 70 inherited metabolic disorders caused by defective lysosomal enzymes or transporters; treated mainly by enzyme replacement therapy since 1991 (Gaucher disease).

Lytico-bodig disease

Lytico-bodig disease, also called ALS/PDC or Guam disease, is a neurodegenerative ALS-parkinsonism-dementia syndrome endemic to the Chamorro people of Guam, peaking in the 1950s and linked to the cycad toxin BMAA hypothesis.

LZM009 (anti-PD-1 antibody)

LZM009, also known as lipustobart (利普苏拜单抗), is a humanized anti-PD-1 monoclonal antibody developed by China's Livzon Mabpharm, trialed in thymic carcinoma and licensed to Bright Peak Therapeutics.

M cone cell

M cone cell (medium-wavelength-sensitive cone, OPN1MW, green cone): retinal photoreceptor peaking near 543 nm, one of three cone classes enabling human trichromatic vision; X-linked gene, deutan color blindness, olo M-only stimulation.

M-1095

M-1095 (sonelokimab, formerly ALX-0761) is a trivalent camelid nanobody inhibiting IL-17A and IL-17F with an albumin-binding domain, developed by MoonLake for psoriasis, psoriatic arthritis, and hidradenitis suppurativa.

M-fluorobenzylguanidine

M-fluorobenzylguanidine (MFBG, florbenguane F 18, IRP 101) is an investigational fluorine-18 PET tracer, a norepinephrine analog taken up via hNET, studied for neuroblastoma, pheochromocytoma/paraganglioma, and cardiac sympathetic imaging, outperforming 123I-MIBG.

M. Paul Capp

M. Paul Capp is an American radiologist who founded and chaired the Department of Radiology at the University of Arizona College of Medicine for 23 years.

Maalox

Maalox, an antacid brand of aluminum hydroxide plus magnesium hydroxide, often with simethicone (Maalox Plus), for heartburn, dyspepsia, and gas; fast-acting MgOH2 balanced against constipating AlOH3, with kidney failure contraindications and 2-hour drug separation.

mAbs

mAbs (Monoclonal antibodies) is a peer-reviewed open-access journal on monoclonal antibody research and therapeutics, launched January 2009 by Landes Bioscience, published by Taylor & Francis since 2015, edited by Janice M. Reichert, ISSN 1942-0862.

MAC'EVAL study

MAC'EVAL (NCT03954509), Needs Assessment of Cancer Patients With Complementary and Alternative Medicines, a completed observational study by Fondation Hôpital Saint-Joseph with 64 participants, assessing cancer patients' CAM needs in two phases.

maca trial (NCT02624648)

NCT02624648, "Effects of Lepidium Meyenii Walp on Sexual Function in Postmenopausal Women" (maca trial): Brazilian phase 1 randomized, double-blind, placebo-controlled study of 144 postmenopausal women, 120-day maca capsules, FSFI primary outcome, no results posted.

MACA trial (NCT05781412)

MACA trial (NCT05781412), Modulation of the Activity of the Cerebellum in Autism: Vrije Universiteit Brussel study testing anodal cerebellar tDCS versus sham on social understanding in autistic and neurotypical adults, 100 participants, UZ Brussel, status unknown, no results posted.

Machine perfusion

Machine perfusion is a transplantation technique that circulates oxygenated fluid through a donor organ between retrieval and implantation, reducing injury compared with static cold storage on ice.

Macimorelin

Macimorelin (AEZS-130, Macrilen, Ghryvelin) is an oral ghrelin-mimetic tripeptide, GHSR agonist, FDA-approved in 2017 to diagnose adult growth hormone deficiency via a 0.5 mg/kg GH stimulation test.

Macitentan

Macitentan, sold as Opsumit, is an oral endothelin receptor antagonist developed by Actelion and approved in the United States in 2013 to reduce the risk of pulmonary arterial hypertension worsening.

MacLeod syndrome

MacLeod syndrome, or Swyer-James-MacLeod syndrome, is a rare acquired unilateral hyperlucent lung caused by postinfectious obliterative bronchiolitis in childhood, with air trapping, oligemia, and possible bronchiectasis; unrelated to X-linked McLeod neuroacanthocytosis.

Macro reentrant atrial tachycardia

Macro reentrant atrial tachycardia (MRAT), also called atypical or macroreentrant atrial flutter, is a reentrant atrial arrhythmia circling a large anatomical obstacle such as the tricuspid annulus, surgical scar, or ablation lines, confirmed by entrainment and treated mainly with catheter ablation.