25,729 articles
Management of polycystic ovary syndrome
Management of polycystic ovary syndrome (PCOS) is the goal-directed medical and lifestyle treatment of a chronic endocrine condition, with combined pills for irregular periods, metformin for metabolic health, and letrozole for infertility.
Management of prostate cancer
Management of prostate cancer, also called active surveillance or watchful waiting for low-risk disease, covers risk-stratified treatment: surgery, radiotherapy, hormone therapy, chemotherapy, and PSMA-targeted radiopharmaceuticals, guided by Gleason score, Grade Group, PSA, and staging.
Management of systemic lupus erythematosus
Management of systemic lupus erythematosus is the long-term treatment of the chronic autoimmune disease, built on universal hydroxychloroquine, minimal glucocorticoids, early immunosuppressives or biologics, and structured monitoring.
Management of systemic sclerosis
Management of systemic sclerosis (SSc) is an organ-based strategy targeting skin fibrosis, lung disease, pulmonary hypertension, Raynaud's, and renal crisis, guided by 2023 and 2024 guidelines.
Manahsila sodhana
Manahsila sodhana is the Ayurvedic purification (Shodhana) of manahshila, realgar or arsenic disulphide (As2S2), an Uparasa mineral drug, classically by seven levigations with ginger juice before therapeutic use.
Manasamitra Vataka
Manasamitra Vataka (Manasamitra Vatakam/Vati/Gulika), classical Ayurvedic herbo-mineral tablet for anxiety, insomnia, and cognitive disorders; 73 ingredients; TGA 2025 advisory found SKM tablets contained mercury, lead, arsenic, cadmium.
Manchester Royal Infirmary
Manchester Royal Infirmary (MRI) is a large NHS teaching hospital on Oxford Road, Manchester, founded in 1752 by Charles White and Joseph Bancroft; part of Manchester University NHS Foundation Trust, with 770 beds, a Major Trauma Centre, and transplant and haematology services.
Manchester triage
Manchester triage, formally the Manchester Triage System (MTS), is a five-category, color-coded method for prioritizing emergency department patients, developed in Manchester, UK, in 1994 and used in countries including Germany and Portugal.
Mandeep R. Mehra
Mandeep R. Mehra (MBBS, MSc, FRCP) is a Harvard cardiologist, William Harvey Chair and medical director of the Brigham and Women's Hospital Heart and Vascular Center, editor of the Journal of Heart and Lung Transplantation, and lead author of the retracted 2020 Lancet and NEJM Surgisphere COVID-19 studies.
Mandible
Mandible: the largest bone of the human skull, forming the lower jaw; articulates at the temporomandibular joints, develops around Meckel's cartilage, and is a common facial fracture site.
Mandibular advancement
Mandibular advancement is a dentistry and sleep medicine treatment that holds the lower jaw forward during sleep, usually with a mandibular advancement device, to treat obstructive sleep apnea and snoring.
Mandibular hypoplasia-deafness-progeroid features-lipodystrophy syndrome
MDPL syndrome (MDP syndrome, OMIM 615381) is an ultra-rare autosomal dominant progeroid lipodystrophy caused by heterozygous POLD1 mutations, most often the recurrent de novo p.Ser605del deletion, causing mandibular hypoplasia, sensorineural deafness, lipodystrophy, and insulin resistance, distinguished from Werner syndrome by absent cataracts.
Mandibular nerve
Mandibular nerve (CN V3, nervus mandibularis), largest trigeminal division and the only one with a motor root; exits via foramen ovale, splits into anterior and posterior divisions, supplies mastication muscles, lower teeth, tongue, and is the target of the inferior alveolar nerve block.
Mandibular osteotomy
A mandibular osteotomy is surgery that cuts and repositions the lower jaw to correct deformity, malocclusion, or sleep apnea, most often via the bilateral sagittal split technique.
Mandibular Prosthesis
Mandibular prosthesis: dental/maxillofacial device replacing missing teeth or jaw segments after mandibulectomy, trauma, or congenital loss. Includes guidance appliances, dentures, implant-supported and patient-specific implants; distinct from generic dental prostheses.
Mandibular Prosthesis Implantation
Mandibular prosthesis implantation (MeSH D019930) is the surgical insertion of an appliance replacing areas of the mandible, covering dental implant prostheses, patient-specific alloplastic jaw implants, and TMJ prostheses after resection, trauma, or bone loss.
Mandibular reconstruction
Mandibular reconstruction is surgery that restores segmental defects of the lower jaw using vascularized bone flaps, bone grafts, or titanium plates, most often a free fibula flap.
Mandibular setback surgery
Mandibular setback surgery is an orthognathic procedure that repositions the lower jaw backward to correct mandibular prognathism and Class III malocclusion, most often by sagittal split ramus osteotomy.
Mandibulectomy
Mandibulectomy is surgery that removes part or all of the lower jaw bone to treat oral cavity tumors or advanced osteoradionecrosis, with marginal, segmental, and hemimandibulectomy types.
Mandibuloacral dysplasia
Mandibuloacral dysplasia (MAD, MADA/MADB) is an ultrarare autosomal recessive progeroid laminopathy with mandibular and clavicular hypoplasia, acro-osteolysis, skin pigmentation changes, and lipodystrophy, caused by LMNA (type A) or ZMPSTE24 (type B) mutations.
Mandibuloacral dysplasia associated to MTX2
MADaM (mandibuloacral dysplasia associated to MTX2, OMIM 619127) is a rare autosomal recessive progeroid syndrome caused by MTX2 mutations, featuring growth retardation, acro-osteolysis, lipodystrophy, renal glomerulosclerosis, and mitochondrial-nuclear linkage.
Mandibulofacial dysostosis with alopecia
Mandibulofacial dysostosis with alopecia (MFDA, OMIM 616367) is a rare autosomal dominant craniofacial disorder caused by de novo gain-of-function EDNRA variants, combining facial bone hypoplasia, ear and eyelid anomalies, conductive hearing loss, and scalp alopecia.
Mandibulofacial dysostosis-microcephaly syndrome
Mandibulofacial dysostosis-microcephaly syndrome (MFDM), also known as mandibulofacial dysostosis, Guion-Almeida type, is a rare genetic disorder caused by EFTUD2 gene mutations, with underdeveloped facial bones, microcephaly, malformed ears, and intellectual disability.
Mandura bhasma (mandira bhasma)
Mandura bhasma (mandur/mandira bhasma, मण्डूर भस्म) is an Ayurvedic iron-oxide calcine made from aged iron slag (fayalite FeSiO4) via shodhana and marana, used for anemia (Pandu) and liver disorders, dose 30–240 mg classical, 250–500 mg official.
MANDURA VATAKA
Mandura Vataka (Maṇḍūra vaṭaka) is a classical Ayurvedic herbo-mineral pill of mandura bhasma (iron), swarnamakshika bhasma, and plant drugs in cow urine, used mainly for Pandu (anemia); AFI identifier AFI000258, dosage 1 g.
Manfidokimab
Manfidokimab (AK120) is Akeso's anti-IL-4Rα monoclonal antibody for moderate-to-severe atopic dermatitis; its Phase III met endpoints in August 2025 and its NMPA NDA was accepted in February 2026.
Manganese deficiency
Manganese deficiency, lack of the trace element Mn, is among the rarest human nutritional deficiencies; only one experimental case (Doisy 1973) exists, with proposed symptoms of poor bone formation, rash, and mood change.
Manganese dioxide nanomedicine
Manganese dioxide nanomedicine uses MnO₂ nanoparticles as diagnostic and therapeutic agents, mainly for cancer imaging and drug delivery, exploiting the chemical conditions of the tumor microenvironment.
Manganese excess
Manganese excess (manganism): neurotoxicity from elevated manganese, causing parkinsonism in adults and cognitive-motor deficits in children; basal ganglia accumulation, biliary excretion, occupational welding/mining and water exposures, FNB UL 11 mg/day adults.
Manganese poisoning
Manganese poisoning, also called manganism, is a neurological condition caused by chronic inhalation of manganese dust or fumes, producing tremor, rigidity, slowed movement, and psychiatric disturbance.