25,729 articles
Multifocal atrial tachycardia
Multifocal atrial tachycardia (MAT), also called chaotic atrial tachycardia, is an irregular arrhythmia with at least three P-wave morphologies at rates over 100 bpm, seen mostly in elderly COPD patients and treated first by correcting underlying causes.
Multifocal cerebral infarctions
Multifocal cerebral infarctions (ICD-11 8E64, postprocedural) are multiple ischemic brain infarcts in several arterial territories; 13% of strokes, usually cardioembolic, common after cardiac surgery, with vasculitis a key differential.
Multifocal ectopic Purkinje-related premature contraction
MEPPC (multifocal ectopic Purkinje-related premature contraction), also called multifocal ectopic premature Purkinje-related complexes, is a rare autosomal dominant SCN5A gain-of-function arrhythmia syndrome with high-burden narrow-QRS Purkinje PVCs, dilated cardiomyopathy, and sudden death risk; treated with flecainide or quinidine.
Multifocal electroretinography
Multifocal electroretinography (mfERG) is an electrophysiological technique that records electrical responses from many retinal regions at once, mapping cone function to detect maculopathies and hydroxychloroquine toxicity.
Multifocal infantile hemangioma with extracutenous involvement
Multifocal infantile hemangioma with extracutenous involvement, once called diffuse neonatal hemangiomatosis, is a rare disorder marked by numerous skin hemangiomas plus hemangiomas of internal organs such as the liver.
Multifocal Intraocular Lenses
Multifocal intraocular lenses (MIOLs), including bifocal, trifocal, refractive, and diffractive designs, are implanted IOLs giving near, intermediate, and distance vision after cataract surgery, trading reduced contrast sensitivity and halos for spectacle independence.
Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome
Multifocal lymphangioendotheliomatosis-thrombocytopenia syndrome (MLT), also called cutaneovisceral angiomatosis-thrombocytopenia syndrome, is a rare lymphatic disorder first described in 2004, with congenital skin and gastrointestinal vascular lesions that deplete platelets and bleed.
Multifocal motor neuropathy
Multifocal motor neuropathy (MMN), also called MMNCB, is a rare immune-mediated purely motor neuropathy with asymmetric distal upper-limb weakness, motor conduction block, anti-GM1 IgM antibodies in 40-50%, and IVIg as first-line therapy.
Multifocal pattern dystrophy simulating fundus flavimaculatus
Multifocal pattern dystrophy simulating fundus flavimaculatus (MPDSFF), also called pseudo-Stargardt pattern dystrophy, is a rare autosomal dominant PRPH2-related retinal pigment epithelium dystrophy with adult-onset yellow flecks, hyperautofluorescence, no dark choroid, and a better prognosis than Stargardt disease.
Multigene assay
A multigene assay is a diagnostic test combining the expression of multiple genes in a tumor into one score, used most often to guide chemotherapy decisions in early breast cancer.
Multigene panel testing
Multigene panel testing is a diagnostic genetic test that sequences many genes linked to one condition in a single assay, used to assess hereditary cancer risk and guide treatment.
Multiloculated renal cyst
The multiloculated renal cyst, also known as multilocular cystic nephroma, is a rare benign kidney tumor of separate cysts, occurring mainly in young children and adults aged 40 to 70, and treated surgically.
Multiminicore myopathy
Multiminicore myopathy, or multiminicore disease (MmD), is a rare congenital myopathy with multiple minicores on muscle biopsy, axial weakness, scoliosis, spinal rigidity, and respiratory insufficiency; SELENON and RYR1 variants cause about half of cases.
Multimorbidity
Multimorbidity, also called multiple chronic conditions (MCC), is the coexistence of two or more chronic conditions in one person; it affects over half of US adults, rises steeply with age, and is measured by counts or weighted indices.
Multinational Association of Supportive Care in Cancer
The Multinational Association of Supportive Care in Cancer (MASCC), founded in 1990, is an international organization advancing supportive cancer care with members in over 80 countries.
Multinucleated neurons-anhydramnios-renal dysplasia-cerebellar hypoplasia-hydranencephaly syndrome
MARCH syndrome (OMIM 236500, ORPHA:500135) is a lethal autosomal recessive CEP55-related disorder with hydranencephaly, cerebellar hypoplasia, renal dysplasia, anhydramnios, Potter sequence, and multinucleated neurons.
Multiparametric magnetic resonance imaging
Multiparametric MRI (mpMRI) combines several MRI sequences, typically T2-weighted anatomy with diffusion-weighted and dynamic contrast-enhanced imaging, and is the standard for diagnosing clinically significant prostate cancer.
Multiparametric ultrasound
Multiparametric ultrasound (MPUS) is an imaging approach that combines several ultrasound parameters, including tissue stiffness, attenuation, backscatter, and speed of sound, to characterize tissue for diagnosis.
Multiphase optimization strategy
The multiphase optimization strategy (MOST) is a framework introduced by Linda M. Collins and colleagues in 2005 for building and optimizing multicomponent behavioral and biomedical interventions.
Multiphasic Screening
Multiphasic screening combines multiple laboratory tests in one examination session to detect several diseases at once, usually in groups of people. First named in San Jose, California, 1949; automated by Kaiser Permanente; controlled trials show no mortality benefit.
Multiplanar reconstruction
Multiplanar reconstruction (MPR), also called multiplanar reformation, is a medical imaging post-processing method that resamples CT or MRI scans into new axial, coronal, sagittal, or oblique 2D images.
Multiple and combined glycosylation defects
Multiple and combined glycosylation defects are rare congenital disorders of glycosylation in which one genetic fault, often in Golgi transport or ion pumps, disrupts multiple glycosylation pathways simultaneously.
Multiple benign circumferential skin creases on limbs
Multiple benign circumferential skin creases on limbs, or circumferential skin creases Kunze type (Michelin tire baby syndrome), a rare genetic disorder from TUBB or MAPRE2 mutations causing ringed limb skin creases with intellectual disability, cleft palate, and dysmorphism.
Multiple breath washout
Multiple breath washout (MBW) is a pulmonary function test that washes a tracer gas from the lungs during tidal breathing; its lung clearance index detects early obstructive lung disease even when spirometry is normal.
Multiple congenital anomalies-hypotonia-seizures syndrome
Multiple congenital anomalies-hypotonia-seizures syndrome (MCAHS), also PIGN-CDG/MCAHS1 (OMIM 614080), a rare autosomal recessive GPI-anchor glycosylation defect with severe developmental delay, hypotonia, early seizures, and cardiac, genitourinary, and gastrointestinal anomalies.
Multiple delivery
Multiple delivery (ICD-11 JB24): birth of more than one infant from one pregnancy, usually twins. Covers US epidemiology, elevated maternal and perinatal risks, and evidence that planned cesarean and planned vaginal twin delivery have similar outcomes.
Multiple drug hypersensitivity syndrome
Multiple drug hypersensitivity syndrome (MDHS, ICD-11 4A85.04): confirmed drug allergies to two or more chemically unrelated drugs, T-cell mediated, distinct from cross-reactivity, flare-up reactions, and nonimmune multiple drug intolerance syndrome.
Multiple Drug Resistance
Multiple drug resistance (MDR, multidrug resistance): simultaneous resistance to several structurally distinct drugs. Covers MDR-TB (isoniazid plus rifampicin resistance), XDR-TB definitions, bacterial efflux and inactivation mechanisms, and cancer ABC-transporter resistance.
Multiple electrode aggregometry
Multiple electrode aggregometry (MEA) is a point-of-care whole-blood test that measures platelet aggregation through electrical impedance between electrode pairs, used to monitor antiplatelet drugs in PCI, surgery, and trauma care.
Multiple endocrine neoplasia
Multiple endocrine neoplasia (MEN1, MEN2, Wermer's syndrome) is a group of autosomal dominant inherited syndromes causing tumors of multiple endocrine glands, driven by MEN1/menin or RET gene mutations.