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Human health and medicine

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Other effects of reduced temperature

Other effects of reduced temperature (ICD-11 NF03; ICD-10 T69) is a classification category for cold injuries other than frostbite and hypothermia, chiefly chilblains and immersion hand or foot (trench foot), non-freezing cold injuries of wet cold exposure.

Other forms of botulism

Other forms of botulism: wound, infant, adult intestinal toxemia, iatrogenic, and inhalation botulism, caused by Clostridium botulinum toxin by routes other than food; infant cases dominate US surveillance.

Other health professionals

Other health professionals is ISCO-08 minor group 226 under Health professionals, covering dentists (2261), pharmacists (2262), physiotherapists, dieticians, audiologists, optometrists, and health professionals not elsewhere classified (2269).

Other parasomnias

Other parasomnias (ICSD-3; ICD-11 code 7B02) is the residual sleep-disorder category for parasomnias independent of sleep stage, including exploding head syndrome, sleep-related hallucinations, and sleep enuresis, distinct from NREM and REM parasomnias.

Other peripheral vertigo

Other peripheral vertigo, ICD-11 code AB34.1 (also indexed as otogenic, auditory, or aural vertigo and Lermoyez syndrome), is the residual WHO category for peripheral vestibular vertigo not classified under a named disorder such as BPPV, vestibular neuritis, or Ménière's disease.

Other serum reactions

Other serum reactions (ICD-11 NE80.3; ICD-10-CM T80.6) is a residual classification for immune reactions to serum proteins after transfusion, infusion, or injection, covering serum sickness, protein sickness, serum rash, and serum urticaria, excluding serum hepatitis and anaphylaxis.

Other specified feeding or eating disorder

Other specified feeding or eating disorder (OSFED), formerly EDNOS, is a DSM-5 diagnosis for eating disorders that fall short of full criteria for anorexia, bulimia, or binge-eating disorder.

Other spontaneous pneumothorax

Other spontaneous pneumothorax, WHO ICD-10 code J93.1, is the category for air in the pleural space arising without trauma or medical intervention other than spontaneous tension pneumothorax.

Otilimab

Otilimab is a monoclonal antibody against GM-CSF developed for rheumatoid arthritis by MorphoSys and GSK, whose phase III program ended in 2022 for limited efficacy.

Otilonium

Otilonium bromide (Spasmomen, Spasmoctyl), a poorly absorbed quaternary ammonium antispasmodic blocking L-type calcium channels, muscarinic and tachykinin receptors; used at 40 mg three times daily for irritable bowel syndrome, superior to placebo with placebo-like tolerability.

Otitic barotrauma

Otitic barotrauma (barotitis media, aero-otitis-media, ear squeeze) is ear injury from failed pressure equalization, usually via Eustachian tube dysfunction, affecting divers and aircrew; middle ear injury predominates, with pain above ~30 mmHg gradients.

Otitis

Otitis, or ear infection and inflammation, includes otitis externa (swimmer's ear), otitis media, otitis media with effusion, and labyrinthitis; most acute otitis media in children resolves without antibiotics.

Otitis externa

Otitis externa, commonly known as swimmer's ear, is inflammation of the external ear canal, often with infection, causing ear pain, itching, and discharge; it occurs in acute, chronic, and necrotising forms.

Otitis media

Otitis media, also called ear infection or middle ear infection, is inflammation of the middle ear behind the eardrum. Types include AOM, OME, and COME; five of six children are affected by age three, treated with watchful waiting, amoxicillin, or tympanostomy tubes.

Otocephaly

Otocephaly, or agnathia-otocephaly complex (OMIM 202650), is a rare lethal congenital malformation with absent mandible, microstomia, aglossia, and midline-fused ears, often with holoprosencephaly; incidence under 1 in 70,000 births, linked to PRRX1.

Otodental syndrome

Otodental syndrome, also called otodental dysplasia or globodontia, is a very rare autosomal dominant disorder causing enlarged bulbous canine and molar teeth plus hearing loss.

Otofaciocervical syndrome

Otofaciocervical syndrome (OTFCS, Fara-Chlupackova syndrome, OFC syndrome) is an ultra-rare genetic disorder with ear, facial, and shoulder girdle anomalies, hearing loss, and mild intellectual disability; EYA1 (type 1) or PAX1 (type 2).

Otolaryngologists

Otolaryngologists (ENT doctors) are head and neck surgeon-physicians treating ear, nose, throat, and related conditions. Five-year residency, ABOHNS certification, subspecialties including neurotology and pediatric otolaryngology.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Otolaryngology–Head and Neck Surgery (Otolaryngol Head Neck Surg, ISSN 0194-5998), the official peer-reviewed monthly journal of the AAO-HNS Foundation, published since 1981, Wiley-published since 2023, 2025 impact factor 2.6.

Otolith

Otolith (otoconia): calcium carbonate crystals in the utricle and saccule of the inner ear's vestibular system, detecting linear acceleration and head tilt relative to gravity; distinct from semicircular canals, tested clinically by VEMP, vOCR, and SVV.

Otologic Surgical Procedures

Otologic surgical procedures are operations on the external, middle, or internal ear (MeSH D013506), including tympanoplasty, mastoidectomy, stapes surgery, and cochlear implantation, with endoscopic techniques now established alongside microscopic surgery.

Otological Diagnostic Techniques

Otological diagnostic techniques (MeSH D003939) are methods for diagnosing ear disease and hearing loss: otoscopy, pure-tone and speech audiometry, tuning fork tests, tympanometry, acoustic reflex, otoacoustic emissions, auditory brainstem response, vestibular tests, imaging, and AI-assisted otoscopy.

Otopalatodigital syndrome type 1

Otopalatodigital syndrome type 1 (OPD1, Taybi syndrome) is a rare X-linked dominant skeletal dysplasia caused by gain-of-function FLNA mutations, the mildest of the otopalatodigital spectrum, with conductive hearing loss, cleft palate, and characteristic facial and digit anomalies.

Otopalatodigital syndrome type 2

Otopalatodigital syndrome type 2 (OPD2, Taybi syndrome) is a rare X-linked FLNA gain-of-function skeletal dysplasia with dysmorphic facies, cleft palate, bowed bones, absent halluces, heart and brain malformations, and early death in affected males.

Otoplasty

Otoplasty is a surgical procedure that reshapes or repositions the external ear, most often to correct prominent ears, usually done at age 5 or 6 under general anesthesia.

Otorhinolaryngologic Surgical Procedures

Otorhinolaryngologic surgical procedures are operations on the ear, nose, and throat, including the adenoids, tonsils, pharynx, and trachea, classified as MeSH descriptor D013517 under Surgical Procedures, Operative.

Otorhinolaryngology

Otorhinolaryngology (ENT, otolaryngology) is the medical specialty for ear, nose, throat, and head and neck disorders. Distinguished by its otology, rhinology, and laryngology roots, endoscopic and robotic surgery, and a global workforce of 2.19 clinicians per 100,000.

Otorrhagia

Otorrhagia (otorragia) is the medical term for bleeding from the ear, ICD-10 H92.2 and ICD-11 AB70.1, distinct from otorrhea and hemotympanum, caused by eardrum perforation, infection, trauma, or tumor.

Otorrhoea

Otorrhoea (otorrhea) is ear discharge, usually from otitis media, otitis externa, or a perforated eardrum; types include purulent, serous, bloody, mucoid, and clear, with CSF leak after head trauma a serious cause.

Otosclerosis

Otosclerosis: abnormal bone remodeling fixing the stapes in the middle ear, causing progressive conductive hearing loss, tinnitus, and sometimes vertigo; treated with hearing aids or stapes surgery (stapedectomy, stapedotomy).