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Peripartum cardiomyopathy
Peripartum cardiomyopathy (PPCM), or postpartum cardiomyopathy, is heart failure with LVEF under 45% arising late in pregnancy or within five months after delivery, with no other cause; incidence about 1 in 2000 births, highest in Nigeria.
Peripartum hysterectomy
Peripartum hysterectomy is the surgical removal of the uterus around the time of childbirth, performed almost always to control life-threatening obstetric hemorrhage, occurring in about 1.1 per 1,000 births worldwide.
Peripartum Period
Peripartum period: the time shortly before, during, and immediately after childbirth (MeSH D058725). Also called peri-partum; distinct from postpartum (mother) and postnatal (baby), with definitions ranging from delivery to 28 days after, or conception to one year postpartum.
Peripheral and visceral arteriovenous malformation
A peripheral or visceral arteriovenous malformation is a congenital tangle of abnormal blood vessels outside the brain and spinal cord, where arteries connect directly to veins.
Peripheral angiography
Peripheral angiography is a fluoroscopy-guided procedure in which catheter-injected iodinated contrast X-rays arteries outside the heart, most often leg arteries in suspected peripheral artery disease.
Peripheral arteriovenous fistula
Peripheral arteriovenous fistula (FAV periférica, ORPHA:708051) is a rare high-flow vascular anomaly with a direct artery-to-vein connection and no nidus; often asymptomatic, it can cause heart failure and pulmonary hypertension.
Peripheral arteriovenous malformations
Peripheral arteriovenous malformations (AVMs), also called peripheral vascular AVMs, are rare fast-flow artery-vein shunts outside the brain, often RAS-pathway driven, treated mainly by ethanol embolization with 69% substantial devascularization.
Peripheral artery aneurysm
A peripheral artery aneurysm is a focal dilation of a non-aortic, non-brain artery, most often popliteal, that tends to clot or shed emboli rather than rupture.
Peripheral artery disease
Peripheral artery disease (PAD), or peripheral arterial disease, is atherosclerotic narrowing of leg arteries causing claudication, ischemia, and amputation risk; diagnosed by ankle-brachial index, treated with exercise, antithrombotics, and revascularization.
Peripheral blood stem cell
Peripheral blood stem cells (PBSC) are blood-forming stem cells collected from circulating blood by apheresis after G-CSF mobilization, used in PBSCT. Since 1986 they replaced marrow in ~75% of allogeneic transplants, with faster engraftment but more chronic GVHD.
Peripheral Blood Stem Cell Transplantation
Peripheral blood stem cell transplantation (PBSCT, peripheral stem cell support): infusion of blood-collected hematopoietic stem cells after high-dose chemotherapy; autologous, allogeneic, or syngeneic; introduced 1986, largely replaced bone marrow grafts.
Peripheral Catheterization
Peripheral catheterization (MeSH D002406): insertion of a catheter into a peripheral artery, vein, or airway for diagnosis or therapy. Includes PIVCs, arterial lines, PICCs; over 1 billion lines yearly; main risks phlebitis, infiltration, failure.
Peripheral demyelinating neuropathy-central dysmyelinating leukodystrophy-Waardenburg syndrome-Hirschsprung disease
PCWH (OMIM 609136), also called neurologic Waardenburg-Shah syndrome or WS4 plus, is a rare autosomal dominant SOX10-related disorder combining Waardenburg-Shah features with demyelinating neuropathy and central leukodystrophy; fewer than 50 cases reported.
Peripheral magnetic stimulation
Peripheral magnetic stimulation (PMS) is a noninvasive neuromodulation technique that uses high-intensity pulsed magnetic fields to activate peripheral nerves and induce painless muscle contractions, used for pain, rehabilitation, and incontinence.
Peripheral nerve stimulation
Peripheral nerve stimulation (PNS) is a neuromodulation technique that delivers electrical pulses to a named peripheral nerve through a nearby lead, reducing chronic neuropathic pain.
Peripheral neuropathy
Peripheral neuropathy is damage to peripheral nerves causing numbness, pain, weakness, or autonomic dysfunction; over 100 types exist. Diabetes is the leading cause, affecting up to 50% of long-term diabetics; monofilament screening sensitivity ranges 41-93%.
Peripheral primitive neuroectodermal tumor
Peripheral primitive neuroectodermal tumor (pPNET, PPNET, ICD-O 9364) is a rare aggressive small round cell sarcoma of bone or soft tissue outside the CNS, part of the Ewing family of tumors with the t(11;22) EWS-FLI1 fusion, peaking in the second decade.
Peripheral pulmonary stenosis
Peripheral pulmonary stenosis (branch pulmonary artery stenosis, PPAS) is narrowing of peripheral pulmonary artery branches, congenital or acquired, linked to Williams and Alagille syndromes; treated by balloon angioplasty, stenting, or surgery.
Peripheral quantitative computed tomography
Peripheral quantitative computed tomography (pQCT) is a low-dose CT technique measuring volumetric bone density and geometry at peripheral sites like the radius and tibia, separating cortical from trabecular bone.
Peripheral retinal degeneration
Peripheral retinal degeneration is a group of acquired or congenital retinal lesions outside the macula in which tissue thins, splits, or atrophies, sometimes leading to rhegmatogenous retinal detachment.
Peripheral spondyloarthritis
Peripheral spondyloarthritis (pSpA) is the peripheral-joint form of spondyloarthritis, marked by arthritis, enthesitis, and dactylitis, classified by 2011 ASAS criteria and distinguished from axial SpA and psoriatic arthritis sine psoriase.
Peripheral T-cell lymphoma not otherwise specified
Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is the most frequent nodal mature T-cell lymphoma, diagnosed by exclusion, with TBX21 and GATA3 molecular subgroups and poor CHOP outcomes.
Peripheral venous malformations
Peripheral venous malformations: common congenital slow-flow vascular malformations of abnormal veins, formerly called cavernous hemangioma, driven by TEK/TIE2 or PIK3CA mutations, treated mainly by sclerotherapy.
Peripheral vision
Peripheral vision is sight outside the fovea, covering about 99.9% of the visual field. Also called indirect or eccentric vision, it is limited mainly by crowding, not blur, and excels at motion and scene gist.
Peripherally inserted central catheter
Peripherally inserted central catheter (PICC): central venous catheter inserted via an arm vein with tip in the lower SVC or cavoatrial junction; first described 1975, used for antibiotics, nutrition, chemotherapy; key risks are bloodstream infection and thrombosis.
Perirectal abscess
Perirectal (perianal, anorectal) abscess: pus collection near the anus, usually cryptoglandular. Treated by incision and drainage; antibiotics and packing have limited roles; fistula follows in a third to half.
Perisplenitis
Perisplenitis, including hyaline perisplenitis (icing-sugar spleen), is inflammation of the splenic capsule and its peritoneal covering, ICD-11 3B81.A; caused by infection, infarction, portal hypertension, or pancreatitis, causing left upper quadrant pain.
Peristalsis
Peristalsis: involuntary wave-like contraction and relaxation of digestive tract muscles propelling contents from pharynx to anus; includes esophageal waves, the fasting migrating motor complex, and disorders such as achalasia and gastroparesis.
Peritoneal abscess
Peritoneal abscess (ICD-11 DC50.2), also called intra-abdominal or intraperitoneal abscess, is a localized pus collection in the peritoneal cavity, usually from perforated appendicitis, diverticulitis, or postoperative leaks; diagnosed by CT (adults) or ultrasound (children) and treated with percutaneous drainage.
Peritoneal adhesions
Peritoneal adhesions, also called intra-abdominal or postoperative adhesions, are fibrous scar bands between peritoneal organ surfaces after surgery; they occur after over 50% of abdominal operations, causing bowel obstruction, pain, and infertility, and are prevented mainly by surgical technique and adhesion barriers.