25,729 articles
Physiology & behavior
Physiology & Behavior is a peer-reviewed academic journal published by Elsevier that covers the causal physiological mechanisms of behavior; it was founded in 1966 by Pergamon Press.
Physiotherapists
Physiotherapists (physical therapists) are rehabilitation professionals treating functional decline through exercise, manual therapy, and physical modalities; title adopted 1966, global body World Physiotherapy (founded 1951) represents 600,000+ members.
Physiotherapy
Physiotherapy, or physical therapy, is the healthcare profession developing, maintaining and restoring movement and functional ability. Covers its World Physiotherapy definition, 1894 CSP origins, global workforce of 600,000+, primary care integration, and Cochrane evidence on exercise, manual therapy, and stroke rehabilitation.
Physostigmine
Physostigmine (eserine), a cholinesterase-inhibiting carbamate alkaloid from the Calabar bean, crosses the blood-brain barrier; used to reverse anticholinergic delirium, historically for glaucoma and myasthenia gravis; first synthesized by Percy Julian in 1935.
PHYTCOVID-19 trial
PHYTCOVID-19 (NCT04501965), a phase 2 three-arm open-label randomized trial in Conakry, Guinea, by the Institute for Research and Development of Medicinal and Food Plants of Guinea, comparing Cinchona-Stevia (CILE) and a four-plant powder (ACAR) against hydroxychloroquine, each with azithromycin, in 231 asymptomatic PCR-confirmed COVID-19 adults; no results posted.
PHYTOME trial
PHYTOME trial (NCT04138654), a Maastricht University dietary intervention in the EU PHYTOME project: plant-extract-enriched, reduced-nitrite processed meats lowered fecal N-nitroso compound excretion in 63 volunteers.
Phytonadione
Phytonadione, also called vitamin K1 or phylloquinone, is a synthetic naphthoquinone vitamin K replacement (C31H46O2, MW 450.7) used to treat hypoprothrombinemia and prevent neonatal vitamin K deficiency bleeding; oral tablets approved 1955, injectable emulsion 1960.
Phytophotodermatitis
Phytophotodermatitis, also called lime disease, is a non-immunologic phototoxic skin reaction caused by furocoumarins (psoralens) from plants such as limes, figs, hogweed, and celery, activated by UVA sunlight, causing streaky blisters and lasting hyperpigmentation.
Phytosome
A phytosome, also called a phyto-phospholipid complex or herbosome, is a delivery system that binds plant-derived actives to phosphatidylcholine to improve absorption, patented by Indena in 1989.
Pibrentasvir
Pibrentasvir is a pan-genotypic hepatitis C NS5A inhibitor developed by AbbVie and marketed as part of glecaprevir/pibrentasvir, sold as Mavyret and approved by the FDA in 2017.
Pica (disorder)
Pica (disorder): eating nonfood, nonnutritive substances for at least one month, also called geophagy, amylophagy, pagophagia; DSM-5 eating disorder affecting children, pregnant women, and people with intellectual disability, linked to iron deficiency.
Picankibart injection
Picankibart injection (匹康奇拜单抗注射液, 信美悦, IBI112) is Innovent Biologics' anti-IL-23p19 monoclonal antibody, the first China-originated IL-23p19 drug, NMPA-approved November 2025 for moderate-to-severe plaque psoriasis with 12-week maintenance dosing.
Piclidenoson
Piclidenoson (CF101, IB-MECA) is Can-Fite BioPharma's oral A3 adenosine receptor agonist, molecular weight 510.29 Da, half-life about 9 hours, in Phase III development for moderate-to-severe plaque psoriasis and Phase 2 programs for Lowe syndrome and canine osteoarthritis.
Picoplatin
Picoplatin (ZD0473, AMD473), a sterically hindered 2-methylpyridine cisplatin analog developed to overcome platinum resistance; tested through phase III in small cell lung cancer but discontinued after failing to show a survival advantage.
Picosulfuric acid
Picosulfuric acid (picosulfate, sodium picosulfate; C18H15NO8S2) is a diphenylmethane stimulant laxative prodrug activated by colonic bacteria to BHPM, used in Picolax/CLENPIQ bowel-cleansing combinations for colonoscopy.
Picovax
Picovax (IPV-Al AJV) is a trivalent aluminium-adjuvanted reduced-dose inactivated polio vaccine by AJ Vaccines, Denmark; licensed 2019, WHO prequalified 21 April 2020, non-inferior to standard IPV in infants.
Picture superiority effect
Picture superiority effect (PSE): memory phenomenon, also called dual-coding advantage, in which pictures are remembered better than words. Named in Paivio & Csapo's 1973 work; distinctiveness experiments eliminated it in recognition.
PICU study
PICU study (NCT05656950), Assessment of Oral Health Status of Patients in Pediatric Intensive Care Units: a completed Turkish observational study; 88 children, mean OAG score 8.45, published in Dimensions of Critical Care Nursing 2024.
Piebaldism
Piebaldism (piebald trait, PBT) is a rare autosomal dominant disorder of melanocyte development caused mainly by KIT mutations, producing congenital stable white skin patches and a white forelock in 80–90% of cases.
PIEBvsPCEA trial
PIEBvsPCEA (NCT03133091) was a randomized double-blind phase 3 trial at Hospital del Rio Hortega, Valladolid, comparing levobupivacaine CEI+PIEB+PCEA versus CEI+PCEA in 200 primiparous labours; PIEB used more drug but needed fewer top-ups and gave higher satisfaction.
Pierpont syndrome
Pierpont syndrome (plantar lipomatosis-facial dysmorphism-developmental delay syndrome, OMIM 602342) is a rare autosomal dominant disorder caused by the de novo TBL1XR1 p.Tyr446Cys variant, with developmental delay, hearing loss, and heel fat pads.
Pierre Robin sequence
Pierre Robin sequence (Robin sequence, PRS/RS): congenital triad of micrognathia, glossoptosis, and upper airway obstruction, often with cleft palate; isolated or syndromic (Stickler, SOX9-related), managed positionally or surgically.
Pierre-Alain Clavien
Pierre-Alain Clavien is a Swiss hepatobiliary and transplant surgeon who led visceral surgery at University Hospital Zurich and created the Clavien-Dindo classification of surgical complications.
Pierson syndrome
Pierson syndrome (microcoria-congenital nephrosis syndrome) is a rare autosomal recessive LAMB2 disorder causing congenital nephrotic syndrome, diffuse mesangial sclerosis, microcoria, and neurodevelopmental deficits; distinct from Posner-Schlossman and Pearson syndromes.
Piezoelectric biomaterials
Piezoelectric biomaterials are biocompatible materials that generate electrical charges under mechanical stress without external power, studied for tissue regeneration, wound healing, biosensing, drug delivery, and antibacterial therapy.
Piezoelectric surgery
Piezoelectric surgery, also called piezosurgery or piezoelectric bone surgery, cuts bone with ultrasonic microvibrations that spare adjacent soft tissue such as nerves, vessels, and mucosa.
Piezosurgery
Piezosurgery, or piezoelectric bone surgery, is a technique that cuts bone with modulated ultrasonic microvibrations, sparing adjacent nerves, blood vessels, and soft tissue; it is used in sinus lift, ridge expansion, and implant site preparation.
Piflufolastat
Piflufolastat (18F-DCFPyL; Pylarify in the US, Pylclari in the EU) is a fluorine-18-labeled PSMA-targeted PET radiotracer for staging and detecting recurrent prostate cancer, FDA approved May 2021.
Pifoxime
Pifoxime (pifoxima, CAS 31224-92-7) is a piperidine oxime NSAID and peripheral analgesic once sold in France as Flamanil and withdrawn after three months for toxicity; usual dose 600 mg/day oral.
Piga khanda
Piga khanda, standardly Pūga Khaṇḍa (पूग खण्ड), also called Supari Paka, is a granular Ayurvedic confection based on purified areca nut, sugar, ghee, milk, amalaki, and shatavari; dosed 5–15 g and indicated for amlapitta, vomiting, vertigo, heart disease, and syncope.