25,729 articles
Plinabulin
Plinabulin (NPI-2358, BPI-2358) is a synthetic diketopiperazine tubulin inhibitor derived from Aspergillus ustus phenylahistin, developed by BeyondSpring as a vascular disrupting agent and non-G-CSF treatment for chemotherapy-induced neutropenia, with phase 3 DUBLIN-3 and PROTECTIVE trials.
Plitidepsin
Plitidepsin (Aplidin, dehydrodidemnin B) is a marine-derived cyclic depsipeptide from Aplidium albicans targeting eEF1A2; approved in Australia (2018) for relapsed/refractory multiple myeloma with dexamethasone, refused in the EU, and trialed against COVID-19.
Plozasiran
Plozasiran (Redemplo, ARO-APOC3) is a GalNAc-conjugated siRNA by Arrowhead Pharmaceuticals that silences APOC3 mRNA; FDA approved November 18, 2025 for familial chylomicronemia syndrome, 25 mg subcutaneously every 3 months.
Plummer–Vinson syndrome
Plummer–Vinson syndrome, also called Paterson–Kelly or sideropenic dysphagia, is a rare triad of dysphagia, iron-deficiency anemia, and postcricoid esophageal webs, mainly in middle-aged women, with increased hypopharyngeal and esophageal cancer risk.
Plumpy'nut
Plumpy'nut is the first ready-to-use therapeutic food (RUTF), a peanut-based fortified paste created in 1996 by Nutriset and André Briend to treat severe acute malnutrition in children at home, with 500 kcal per 92 g sachet.
PLUSO trial
PLUSO trial (NCT06632184), a phase IV triple-blind pilot RCT at IMSS Guadalajara testing 8 mg intraperitoneal ondansetron plus saline lavage versus saline alone for pain and PONV after laparoscopic cholecystectomy.
Plyometrics
Plyometrics: jump and shock training using the stretch-shortening cycle, coined by Fred Wilt in 1975 from Verkhoshansky's methods; improves jump, sprint, and power performance and is safe in older adults when programmed properly.
PMM2-CDG
PMM2-CDG, also known as Jaeken syndrome, is an autosomal recessive inherited disorder caused by deficient phosphomannomutase 2, accounting for about 60% of congenital disorders of glycosylation.
PMTforDR-TB study
PMTforDR-TB (Probe Melting Technology for Rapid Detection of Drug Resistant Tuberculosis) is a multicenter observational study in China, sponsored by Beijing Hospital, evaluating rapid molecular detection of drug-resistant pulmonary tuberculosis.
PNEUBEVAX 14
PNEUBEVAX 14 is a 14-valent pneumococcal conjugate vaccine made in Hyderabad, India, by Biological E, WHO prequalified in 2025 for active immunization of children against invasive pneumococcal disease.
Pneucolin (nasal-spray influenza-vector COVID-19 vaccine)
Pneucolin (dNS1-RBD, DelNS1-nCoV-RBD LAIV) is an intranasal spray COVID-19 vaccine using an NS1-deleted live H1N1 influenza vector expressing SARS-CoV-2 RBD, developed by Wantai, Xiamen University and HKU; EUA in China 2022, phase 3 efficacy 28.2% overall.
Pneumatic otoscopy
Pneumatic otoscopy is a diagnostic examination in which a pneumatic otoscope puffs air against the eardrum to judge its movement, directly testing for middle ear effusion.
Pneumatic retinopexy
Pneumatic retinopexy is an office-based procedure that repairs selected retinal detachments by injecting an expandable gas bubble to seal the retinal break while the retina reattaches.
Pneumococcal 15 valent conjugate vaccine
Pneumococcal 15-valent conjugate vaccine (PCV15, Vaxneuvance, Merck) covers 15 S. pneumoniae serotypes including 22F and 33F; FDA-approved 2021 for adults, 2022 for children; non-inferior to PCV13.
Pneumococcal 21 valent conjugate vaccine
Pneumococcal 21 valent conjugate vaccine (PCV21), sold as CAPVAXIVE, is a pneumococcal vaccine by Merck approved in 2024, the first designed for adults rather than children.
Pneumococcal conjugate vaccine
Pneumococcal conjugate vaccine (PCV; PCV7, PCV10, PCV13, PCV15, PCV20, PCV21): vaccine against Streptococcus pneumoniae using protein-conjugated capsular polysaccharides, giving infant efficacy, herd immunity, and serotype replacement issues.
Pneumococcal meningitis
Pneumococcal meningitis, bacterial meningitis caused by Streptococcus pneumoniae (pneumococcus); leading cause of bacterial meningitis in Europe and the US, with 16-37% mortality, treated with ceftriaxone plus dexamethasone and prevented by conjugate vaccines.
Pneumococcal vaccine
Pneumococcal vaccines (PCV15, PCV20, PCV21, PPSV23) protect against Streptococcus pneumoniae. Conjugate vaccines work in infants via T-dependent responses; US routine use covers children under 5 and adults 50+.
Pneumoconiosis
Pneumoconiosis, also called black lung in coal workers, is a group of occupational lung diseases from inhaled mineral dust, chiefly asbestosis, silicosis, and coal workers' pneumoconiosis, causing progressive fibrosis with no cure.
Pneumoconiosis associated with tuberculosis
Pneumoconiosis associated with tuberculosis, also called silicotuberculosis, is the co-occurrence of mineral-dust fibrotic lung disease with tuberculosis; ICD-11 code CA60.3, ICD-10 J65, pooled TB relative risk 4.01 with silicosis.
Pneumocystis pneumonia
Pneumonia due to pneumocystis (PCP, PJP) is a fungal lung infection caused by Pneumocystis jirovecii, mainly affecting people with advanced HIV (CD4 <200) or other immunosuppression; treated with TMP-SMX for 21 days.
Pneumoencephalography
Pneumoencephalography (PEG), a historical brain-imaging technique introduced by Walter Dandy in 1919 and independently by Adolf Bingel, replaced cerebrospinal fluid with air via lumbar puncture to X-ray the ventricles; CT made it obsolete in the 1970s.
Pneumologie
Pneumologie is the German-language journal of respiratory medicine published by Georg Thieme Verlag, official organ of the German Respiratory Society (DGP); founded 1947 as Der Tuberkulosearzt, named Pneumologie since 1989.
Pneumonectomy
Pneumonectomy is the surgical removal of an entire lung, performed mainly for advanced lung cancer and mesothelioma; the first successful one was reported by Evarts Graham in 1933.
Pneumonia
Pneumonia, a lung infection filling the alveoli with pus and fluid, caused by bacteria, viruses, fungi, or parasites; types include community-acquired, healthcare-acquired, and ventilator-associated; leading infectious killer of children worldwide.
Pneumonia due to Adenovirus
Pneumonia due to adenovirus (HAdV pneumonia, adenoviral pneumonia): lung infection by non-enveloped dsDNA adenoviruses, mainly types 3 and 7, affecting young children and immunocompromised adults; PCR-diagnosed, no approved antivirals, military-only vaccine.
Pneumonia due to Escherichia coli
Pneumonia due to Escherichia coli (E. coli pneumonia, ICD-11 CA40.01, ICD-10 J15.5) is a gram-negative bacterial lung infection with fever, cough, and dyspnoea, mainly hospital-acquired or affecting older adults, with notable fluoroquinolone resistance.
Pneumonia due to Haemophilus influenzae
Pneumonia due to Haemophilus influenzae (ICD-11 CA40.02), bacterial pneumonia from gram-negative H. influenzae, mainly Hib and nontypeable strains; fever, productive cough, treated with antibiotics, prevented by Hib conjugate vaccine.
Pneumonia due to Klebsiella pneumoniae
Pneumonia due to Klebsiella pneumoniae (klebsiella lobar pneumonia, Friedländer's bacillus pneumonia), ICD-11 CA40.03: gram-negative capsular bacillus causing lobar pneumonia with currant-jelly sputum, bulging fissure sign, abscess and empyema, hypervirulent K1 strains, and high antibiotic resistance.
Pneumonia due to Mycoplasma pneumoniae
Pneumonia due to Mycoplasma pneumoniae (walking pneumonia, atypical pneumonia): a mild, gradual-onset community-acquired bacterial pneumonia caused by a wall-less bacterium, treated with macrolides, tetracyclines, or fluoroquinolones, with rising macrolide resistance in Asia.