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Human health and medicine

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Rev neurol

Rev Neurol is an NLM journal abbreviation shared by two neurology journals: Revista de neurologia (Spain, founded 1972, ISSN 0210-0010) and Revue Neurologique (Paris, founded 1893, ISSN 0035-3787, official journal of the Société Française de Neurologie).

Revakinagene taroretcel lwey

Revakinagene taroretcel-lwey (ENCELTO, NT-501) is a Neurotech Pharmaceuticals encapsulated cell gene therapy implant releasing CNTF, FDA-approved March 5, 2025 as the first treatment for adults with idiopathic macular telangiectasia type 2.

Revamilast

Revamilast (GRC 4039) is an oral, selective PDE4 inhibitor developed by Glenmark Pharmaceuticals for inflammatory conditions; it reached phase 2 trials in asthma and rheumatoid arthritis but development is discontinued or unknown.

Revascularization strategy in chronic coronary disease

Revascularization strategy in chronic coronary disease is the choice among PCI, CABG, and medical therapy for stable disease, relieving angina and improving survival in selected anatomic subsets.

Revefenacin

Revefenacin (Yupelri, TD-4208) is a once-daily, nebulized long-acting muscarinic antagonist approved by the FDA in November 2018 for COPD maintenance, the only once-daily nebulized LAMA, dosed 175 mcg/3 mL via standard jet nebulizer.

Reveglucosidase alfa

Reveglucosidase alfa (BMN 701, GILT-tagged rhGAA) was BioMarin's investigational IGF2-tagged enzyme replacement therapy for late-onset Pompe disease; its phase 1/2 trial showed respiratory gains but dose-related hypoglycemia, and the program was discontinued in 2016 without approval.

Reverse immunology

Reverse immunology is a computational approach that predicts T-cell or B-cell epitopes directly from pathogen or tumor genome sequences, inverting classical epitope discovery to identify vaccine and immunotherapy targets without growing the organism.

Reverse sneezing

Reverse sneezing (paroxysmal respiration) is a nasopharyngeal irritation reflex in dogs and cats causing rapid, loud inward inhalations with extended neck; usually benign, common in small and brachycephalic dogs, often idiopathic.

Reverse vaccinology

Reverse vaccinology is a bioinformatics method for vaccine development that screens a pathogen's genome sequence in silico to select candidate protein antigens, without culturing the pathogen.

Reversible cerebral vasoconstriction syndrome

Reversible cerebral vasoconstriction syndrome (RCVS), also called Call-Fleming syndrome, causes recurrent thunderclap headaches with multifocal cerebral artery narrowing that reverses within 3 months; triggered by postpartum state and vasoactive drugs, mainly affecting women.

Reversible inhibition of sperm under guidance

RISUG (Reversible Inhibition of Sperm Under Guidance) is an Indian injectable male contraceptive: styrene maleic anhydride in DMSO injected into the vas deferens, disrupting sperm membranes. Phase III trials in India showed 99.02% efficacy; human reversibility unproven.

Revesz syndrome

Revesz syndrome, also called dyskeratosis congenita with bilateral exudative retinopathy or Revesz-DeBuse syndrome, is an extremely rare autosomal dominant TINF2-related severe variant of dyskeratosis congenita marked by exudative retinopathy, intracranial calcifications, and early bone marrow failure.

Review and annual journals in neuroscience

Review and annual journals in neuroscience, chiefly the Annual Review of Neuroscience (est. 1978, ISSN 0147-006X) and Nature Reviews Neuroscience (est. 2000), publish commissioned surveys of the field rather than primary research, with distinct open access and subscription models.

Review of systems

Review of systems (ROS): structured symptom inventory by organ system, part of the medical history, distinct from the HPI. 14 systems; problem pertinent, extended (2–9), or complete (10+); no longer counted for CMS billing since 2021.

Revised Cardiac Risk Index

Revised Cardiac Risk Index (RCRI, Lee index): 1999 six-point perioperative cardiac risk score for noncardiac surgery, derived from 2893 patients; threshold above 1 marks elevated MACE risk; weak in vascular surgery.

Revised Trauma Score

The Revised Trauma Score (RTS) is a physiological scoring system introduced in 1989 that grades injury severity from Glasgow Coma Scale, blood pressure, and respiratory rate for trauma triage.

Revision ACL reconstruction

Revision ACL reconstruction is surgery replacing a failed ACL graft with a new graft to restore knee stability; up to 13,000 are performed yearly in the United States.

Revision anterior cruciate ligament reconstruction

Revision anterior cruciate ligament reconstruction is surgery that replaces a failed prior ACL graft with a new one, done in one or two stages, with worse outcomes than primary reconstruction.

Revision arthroplasty

Revision arthroplasty is surgery to replace or repair a failed joint prosthesis, such as a hip or knee replacement, caused by loosening, infection, or wear.

Revision rhinoplasty

Revision rhinoplasty, also called secondary rhinoplasty, is a surgical procedure in otolaryngology and plastic surgery that corrects functional or cosmetic problems remaining after a previous rhinoplasty.

Revumenib

Revumenib (Revuforj, SNDX-5613) is the first-in-class oral menin inhibitor from Syndax, FDA-approved in 2024 for relapsed/refractory KMT2A-rearranged acute leukemia and in 2025 for NPM1-mutated AML.

Reward system

Reward system: brain circuitry (VTA, nucleus accumbens, ventral pallidum, prefrontal cortex) mediating wanting, liking, and learning. Dopamine encodes prediction errors and incentive salience, not pleasure itself; dysfunction links to addiction, depression, Parkinson's.

Rewarming

Rewarming: restoration of core body temperature in hypothermia (below 35°C), by passive insulation, active external heat, warmed fluids or lavage, and extracorporeal methods such as CPB and ECMO.

REWIND trial

REWIND (Researching Cardiovascular Events with a Weekly INcretin in Diabetes) was a 9901-patient randomized trial showing dulaglutide 1.5 mg weekly reduced major adverse cardiovascular events by 12% in type 2 diabetes.

Rexlemestrocel-L (Revascor; MPC-06-ID)

Rexlemestrocel-L (Revascor, MPC-06-ID) is Mesoblast's allogeneic STRO-3-immunoselected mesenchymal precursor cell therapy in Phase 3 for chronic low back pain from degenerative disc disease and for heart failure, with RMAT designation and a BLA filed for LVAD patients.

Rey–Osterrieth complex figure test

The Rey–Osterrieth complex figure test (RCFT) is a neuropsychological test assessing visuospatial ability and visual memory, in which a person copies a complex figure and later draws it from memory.

Reye syndrome

Reye syndrome, also called Reye hepatocerebral syndrome, is a rare childhood illness with brain swelling and fatty liver that follows viral infections and has been linked to aspirin.

Reynolds syndrome

Reynolds syndrome, also called PACK syndrome, is a rare autoimmune overlap of primary biliary cholangitis and limited cutaneous systemic sclerosis, first described by Telfer B. Reynolds in 1971, with onset at ages 30-65, mainly in women.

Rezivertinib mesylate (BPI-7711)

Rezivertinib mesylate (BPI-7711, 瑞必达, 甲磺酸瑞齐替尼胶囊) is a third-generation EGFR tyrosine kinase inhibitor from Beta Pharma, approved in China in May 2024 for EGFR T790M-mutated NSCLC after EGFR-TKI progression, dosed 180 mg once daily.

Rezvilutamide

Rezvilutamide (SHR3680, Ariane) is an oral nonsteroidal androgen receptor antagonist by Jiangsu Hengrui, approved in China in 2022 for high-volume metastatic hormone-sensitive prostate cancer based on the CHART trial versus bicalutamide.