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Human health and medicine

25,729 articles

Sexual addiction

Sexual addiction, also called hypersexual disorder or out-of-control sexual behavior, is a proposed pattern of uncontrolled sexual behavior; not in DSM-5, its ICD-11 counterpart is compulsive sexual behavior disorder (CSBD), an impulse control disorder.

Sexual anhedonia

Sexual anhedonia is reduced or absent pleasure from sexual activity; the orgasm-limited form, orgasmic anhedonia or pleasure-dissociative orgasmic dysfunction (PDOD), is ejaculation or orgasm without pleasure, distinct from anorgasmia, with limited treatment data.

Sexual arousal disorder

Sexual arousal disorder, or female sexual arousal disorder (FSAD), is a sexual dysfunction of reduced genital and subjective arousal despite desire and stimulation; DSM-5 now classifies it as female sexual interest/arousal disorder (FSIAD), distinct from persistent genital arousal disorder.

Sexual dysfunction

Sexual dysfunction, also called sexual disorder, is the inability to participate in sexual relationships as wished, affecting about 31% of men and 41% of women; it spans desire, arousal, orgasm, pain, and ejaculation problems, treated with psychotherapy, PDE5 inhibitors, flibanserin, and testosterone.

Sexual fantasy

Sexual fantasy, also called erotic fantasy or sexual daydream, is imagined sexual content that arouses. Research shows few fantasies are rare; 68.8% report BDSM fantasies; only 1.7% of men with paraphilic fantasies feel distress.

Sexual headache

Sexual headache, or primary headache associated with sexual activity (PHASA, coital cephalalgia), is an ICHD-3 primary headache disorder triggered only by sexual activity, typically dull then explosive at orgasm, more common in males, and diagnosed only after excluding subarachnoid hemorrhage, RCVS, and dissection.

Sexual health

Sexual health, also termed sexual well-being, is WHO's positive state of physical, emotional, mental and social well-being in relation to sexuality, requiring safety, pleasure, and sexual rights, not merely absence of disease; distinct from the CSIRO journal Sexual Health.

Sexual stimulation

Sexual stimulation: any physical or psychological trigger of the human sexual response, described in Masters and Johnson's four-phase cycle (excitement, plateau, orgasm, resolution) and studied through genital measures, brain imaging, and later desire-phase and circular models.

Sexuality after spinal cord injury

Sexuality after spinal cord injury (SCI): how lesion level and completeness change arousal, erection, ejaculation, lubrication, orgasm, and fertility, plus assessment tools (IIEF, FSFI) and rehabilitation approaches.

Sexually transmitted infection

Sexually transmitted infection (STI), also called STD: infection with any of over 30 pathogens acquired through sexual contact. WHO estimated 374 million new curable STI cases in 2020; US 2024 cases fell to 2.25 million.

Sexually transmitted infections in the pornography industry

Sexually transmitted infections in the pornography industry, also called adult film industry STIs, are an occupational health issue: frequent testing systems (AIM, PASS), documented HIV outbreaks in 2004 and 2014, and California condom regulations such as Measure B.

Seymour Perry

Seymour Perry (died 2000) was an American physician and pioneer of health technology assessment, first director of the National Center for Health Care Technology and founder of ISTAHC.

Sézary syndrome

Sézary syndrome (SS), leukemic variant of cutaneous T-cell lymphoma first described by Sézary and Bouvrain in 1938, causes erythroderma and pruritus; diagnosis requires ≥1000 Sézary cells/μL, CD4/CD8 ratio ≥10, and CD7/CD26 loss.

SF-36

The SF-36 is a 36-item self-report questionnaire measuring health status across eight scales and physical and mental summary scores, the most widely used quality-of-life measure in research.

SF268

SF268 (SF-268, CVCL_1689) is a human glioblastoma/astrocytoma cell line from the right parietal lobe, established in 1987, an NCI-60 CNS drug-screen line with homozygous TP53 p.Arg273His and a flagged Y-chromosome identity issue.

SF295

SF295 (SF-295, CVCL_1690) is a human glioblastoma cell line established at UCSF from a 67-year-old woman's left temporal lobe tumor; an NCI-60 CNS panel line with PTEN, TP53, and TERT promoter mutations.

SFSS trial

SFSS trial (Spinal Fusions Steroid Study, NCT05287035), University of Texas at Austin Early Phase 1 randomized triple-blind trial of perioperative IV dexamethasone versus saline in 70 children aged 10 to 18 undergoing posterior spinal fusion for adolescent idiopathic scoliosis.

Sgarbossa's criteria

Sgarbossa's criteria: three 1996 GUSTO-1-derived ECG findings (concordant ST elevation, V1-V3 ST depression, excessive discordant ST elevation) for diagnosing myocardial infarction in left bundle branch block or paced rhythm; Smith's 2012 modification uses an ST/S ratio of 0.25.

SGLT2 inhibitor

SGLT2 inhibitors, or gliflozins (canagliflozin, dapagliflozin, empagliflozin), are diabetes drugs that block renal glucose reabsorption, causing glucosuria; developed from phlorizin, they now also treat heart failure and chronic kidney disease.

Shaken baby syndrome

Shaken baby syndrome (SBS), renamed abusive head trauma (AHT) by the AAP in 2009, is a diagnosis attributing the infant triad of subdural hemorrhage, retinal hemorrhage, and encephalopathy to violent shaking; incidence 25–35 per 100,000 under age 1, fatal in about one quarter of cases, and scientifically contested.

Sham feeding

Sham feeding is a diagnostic procedure in which a person chews appetizing food and spits it out without swallowing, testing whether the vagus nerves are intact.

Shanghai Children's Medical Center

Shanghai Children's Medical Center (上海儿童医学中心), a tertiary A-level children's hospital in Pudong, Shanghai, co-founded with Project HOPE, opened 1998, National Children's Medical Center since 2017, Zhangjiang campus 2024.

Shanhu Yanfang

珊瑚验方 (Tibetan: 朱如道沙拉), a late-19th-century Mongolian medical formulary written in Tibetan verse by 伊喜当增旺吉拉 of Yeke Juu League, with 220 formulas and 38 processing methods; source of classic Mongolian formulas such as 明月汤.

Shanxi Medical University

Shanxi Medical University (山西医科大学), public medical university in Taiyuan, Shanxi, China; founded 1919 as Shanxi Medical Training School, renamed Shanxi Medical University 1996; known for physiology, forensic medicine, and ESI top-1% clinical medicine.

Shaoyao Tang

Shaoyao Tang (芍药汤, Peony Decoction), a nine-herb classical Chinese formula from the Jin dynasty Suwen Bingji Qiyi Baoming Ji, clears heat and dampness and regulates qi and blood for damp-heat dysentery; now used mainly for ulcerative colitis.

Sharad Panday

Sharad Panday (1934–2004), Indian cardiothoracic surgeon at KEM Hospital, Mumbai; with P.K. Sen performed India's first heart transplant (16 February 1968, sixth worldwide); devised the Panday shunt for mitral valve replacement; father of actor Chunky Panday.

Shared medical appointments

A shared medical appointment, also called a group medical visit, is a clinical encounter where patients with a similar condition are seen together by a clinician team.

SHARED study

SHARED study (NCT04755881), a terminated Université de Sherbrooke observational trial in Saguenay, Quebec, testing clinical decision rules for early emergency discharge after anaphylaxis; all three rules failed interim validation.

Shashen Maidong Decoction

Shashen Maidong Decoction (沙参麦冬汤) is a Qing-era Chinese medicine moistening-dryness formula from Wenbing Tiaobian (1798) by Wu Jutong; seven sweet-cold herbs nourish lung and stomach yin for dry cough, thirst, and dryness injury.

Shashi-Pena syndrome

Shashi-Pena syndrome (SHAPNS, OMIM 617190) is an ultra-rare autosomal dominant disorder caused by de novo truncating ASXL2 variants, featuring glabellar nevus simplex, macrocephaly, hypotonia, and variable intellectual disability.