72,234 articles
MiR-124
MiR-124 (microRNA-124) is a small non-coding RNA of about 22 nucleotides, the most abundant microRNA in the adult mouse brain, where it suppresses non-neuronal genes and helps maintain neuronal identity.
Mir-126
miR-126 (MIR126, microRNA-126) is an endothelial-specific human microRNA on 9q34.3, encoded in an intron of EGFL7, that regulates angiogenesis via SPRED1 and PIK3R2 and is studied as a biomarker in cancer and cardiovascular disease.
MiR-132
MiR-132 (microRNA-132) is a ~22-nucleotide non-coding RNA from the miR-132/212 cluster on human chromosome 17, CREB-regulated by neuronal activity, repressing targets like p250GAP, and implicated in Alzheimer's disease and heart failure therapy.
Mir-196 microRNA precursor family
Mir-196 microRNA precursor family: three human genes (MIR196A1, MIR196A2, MIR196B) embedded in HOXB, HOXC, HOXA clusters; targets HOXB8 by mRNA cleavage, patterns vertebrae and limbs, and serves as a context-dependent cancer biomarker.
MiR-203
MiR-203 (MIR203A, hsa-mir-203a) is a keratinocyte-specific microRNA at human 14q32.33 that promotes epidermal differentiation by repressing p63, Skp2, and Msi2; upregulated in psoriasis, tumor-suppressive in skin cancers and melanoma.
Mir-205
miR-205 (microRNA-205, MIR205/MIR205HG, 1q32.2) is a conserved epithelial microRNA that represses targets like ZEB1/ZEB2, acting as tumor suppressor or oncomiRNA depending on context.
MiR-208
MiR-208 (miR-208a, miR-208b) is a cardiac microRNA family encoded in introns of the myosin heavy chain genes Myh6 and Myh7, required for stress-induced cardiac hypertrophy and studied as a circulating biomarker of myocardial infarction.
miR-29 family
The miR-29 family is a group of three microRNAs, miR-29a, miR-29b, and miR-29c, encoded from four genes on chromosomes 1 and 7, that repress extracellular matrix genes and curb fibrosis.
Mir-31
Mir-31 (miR-31), a conserved microRNA from the MIR31HG host gene on 9p21.3, regulates keratinocyte migration, wound healing, and skin aging, and acts as a tumor suppressor in adenocarcinoma but oncogene in squamous cell carcinoma.
MIR125A
MIR125A (hsa-mir-125a) is a human microRNA gene. It encodes microRNA 125a, a non-coding RNA that guides gene silencing by binding to target mRNAs and regulating cell proliferation and apoptosis.
MIR137
MIR137 (miR-137) is a human microRNA gene on chromosome 1p21.3 encoding a 23-nt brain-enriched non-coding RNA that regulates neural stem cell differentiation, is genetically linked to schizophrenia via MIR137HG/rs1625579, and acts as a methylation-silenced tumor suppressor.
MIR140
MIR140 (microRNA 140, MIRN140, mir-140) is a human chromosome 16q22.1 non-coding RNA gene inside WWP2 intron 15 producing cartilage-specific miR-140-5p/-3p; it regulates HDAC4 and ADAMTS5, and its mutation causes spondyloepiphyseal dysplasia MIR140 type.
MIR141
MIR141 (hsa-mir-141, HGNC:31528) is a human microRNA gene at 12p13.31, member of the miR-200 family clustered with miR-200c; it represses HIPK2, inhibits EMT, and is studied as a cancer biomarker.
MIR142
MIR142 is a human non-coding RNA gene at 17q22 that encodes microRNA miR-142, key to blood cell development and the most frequently mutated microRNA gene in cancer.
MIR143
MIR143 (microRNA 143) encodes miR-143, a tumor-suppressive microRNA at human 5q32 clustered with miR-145; it regulates KRAS/ERK5 signaling, smooth muscle differentiation, insulin-AKT metabolism, and granulosa cell steroidogenesis.
MIR144
MIR144 (hsa-mir-144, microRNA 144), 17q11.2, encodes miR-144 of the GATA-1-regulated miR-144/451 cluster essential for erythropoiesis; knockout causes anemia; also a disease biomarker.
MIR145
MIR145, also written miR-145, is a human gene on chromosome 5 that makes microRNA-145, a short RNA acting as a tumor suppressor and vascular smooth muscle regulator.
MIR148A
MIR148A (miR-148a, hsa-mir-148a) is a human microRNA gene on chromosome 7p15.2 encoding a tumor-suppressive, inflammation-regulating microRNA of the miR-148/-152 family, dysregulated in many cancers.
MIR150
MIR150 (microRNA 150, miR-150) is a human microRNA gene at 19q13.33 encoding miR-150-5p, a RISC-loaded guide RNA regulating B and T cell development and studied as a diagnostic biomarker in cancer.
MIR155
MIR155 (microRNA 155, also MIRN155, mir-155) is a human non-coding RNA gene at 21q21.3 inside the MIR155HG/BIC host gene, encoding the oncomiR miR-155-5p, a key regulator of immunity, inflammation, cancer, and cardiovascular disease.
MIR15A
MIR15A (hsa-mir-15a) is a human microRNA gene at 13q14.2, cotranscribed with MIR16-1; deleted or downregulated in about two-thirds of CLL cases, it represses BCL2, MCL1, Cyclin D1, ROR1, and TP53 as a tumor suppressor.
MIR17
MIR17 (microRNA 17, hsa-mir-17) is a human non-coding RNA gene at 13q31.3, one of six miRNAs of the miR-17~92 cluster (oncomiR-1) in MIR17HG, an oncogenic microRNA regulating target mRNAs via RISC.
MIR17HG
MIR17HG (C13orf25, MIRHG1), the miR-17-92a-1 cluster host gene at 13q31.3, is an oncogenic human lncRNA hosting six microRNAs, amplified in lymphomas, deleted in Feingold syndrome 2, and targeted by antisense therapy.
MIR195
MIR195 (microRNA 195, miR-195) is a human non-coding RNA gene at 17p13.1 encoding a miR-15/107 family microRNA, studied as a circulating cancer biomarker and generally tumor-suppressive regulator.
MIR200C
MIR200C (microRNA 200c, miR-200c) is a human non-coding RNA gene on chromosome 12, member of the five-member miR-200 family, that represses EMT by targeting ZEB1/ZEB2 and acts as a metastasis suppressor and cancer biomarker.
MIR204
MIR204 (miR-204, hsa-mir-204) is a human microRNA gene at 9q21.12, intragenic within TRPM3, highly expressed in eye tissues, a tumor suppressor, and linked to retinal dystrophy-iris coloboma-congenital cataract syndrome.
MIR206
MIR206 (microRNA 206, hsa-mir-206) is a human non-coding RNA gene at 6p12.2 encoding a skeletal-muscle-specific microRNA of the miR-1/206 family, involved in myogenesis and studied as a biomarker in muscular dystrophy, ALS, SMA, and Alzheimer's disease.
MIR21
MIR21 (miR-21, hsa-mir-21), human microRNA gene at 17q23.1 producing a ~22-nt non-coding RNA; an oncomiR up-regulated in nearly all cancers, heart failure, and fibrosis, but a non-specific biomarker claimed by at least 29 diseases.
MIR210
MIR210 (microRNA 210, miR-210), the master hypoxamir on chromosome 11p15.5, is HIF-1α-induced under hypoxia, targets ISCU and EFNA3, is upregulated in most cancers, and serves as a candidate non-invasive liquid-biopsy biomarker.
MIR214
MIR214, or microRNA 214, is a human gene on chromosome 1q24.3 encoding microRNA-214, a non-coding RNA that represses gene expression and acts in cancer, heart, and kidney biology.