72,234 articles
MIR22
MIR22 (microRNA 22, hsa-miR-22-3p, MIRN22) is a human microRNA gene at 17p13.3 hosted by MIR22HG; it targets PTEN and TET2, acts context-dependently in cancer, metabolism, and heart disease.
MIR221
MIR221 (microRNA 221, hsa-mir-221) is a human Xp11.3 non-coding RNA gene co-transcribed with miR-222; an oncomiR targeting p27, p57, and PTEN, studied as a cancer biomarker and target of the LNA-i-miR-221 inhibitor.
MIR223
MIR223 (microRNA 223, miR-223) is a human Xq12 non-coding RNA gene encoding a microRNA that regulates myeloid differentiation and innate immunity, acts as oncogene or tumor suppressor by tissue context, and serves as a circulating cancer biomarker.
MIR27A
MIR27A (microRNA 27a, hsa-mir-27a) is a human non-coding RNA gene at 19p13.12 producing the 22-nt miR-27a, which represses target mRNAs via RISC and acts as oncogene or tumor suppressor in cancer.
MIR29A
MIR29A (microRNA 29a, hsa-mir-29a, HGNC:31616) is a human non-coding RNA gene on chromosome 7q32.3 encoding miR-29a, a tumor-suppressive, antifibrotic microRNA clustered with miR-29b-1 and studied as a biomarker in cancer, fibrosis, and HIV-1.
MIR30A
MIR30A (microRNA 30a, HGNC:31624) is a human ncRNA gene at 6q13 producing miR-30a-5p and -3p strands; a miR-30 family tumor suppressor studied in renal cell carcinoma and kidney disease biomarkers.
MIR34A
MIR34A (microRNA 34a, miR-34a) is a human non-coding RNA gene on chromosome 1 encoding a p53-regulated tumor-suppressive microRNA of the miR-34 family; its liposomal mimic MRX34 was the first miRNA cancer therapy tested in patients.
MIR375
MIR375 (miR-375, hsa-mir-375) is a human microRNA gene at 2q35, first identified in pancreatic islets as a regulator of insulin secretion and beta-cell mass, and studied as a circulating diagnostic biomarker in prostate and other cancers.
MIR941-1
MIR941-1 (microRNA 941-1, HGNC:33684) is a human ncRNA gene at 20q13.33 producing miR-941, a human-specific microRNA that arose de novo from tandem repeats one to six million years ago and targets hedgehog and insulin signaling genes.
Mirabegron
Mirabegron (Myrbetriq, Betmiga) is a beta-3 adrenergic receptor agonist for overactive bladder, approved in the US in June 2012, recommended by NICE when antimuscarinics fail, with lower dry mouth risk but modest blood pressure increase.
Mirabelle plum
Mirabelle plum, a small sweet yellow plum of Prunus domestica, also called mirabelle de Lorraine; IGP fresh fruit since 1996, AOC eau-de-vie, centered on Lorraine, France.
Mirabilis jalapa
Mirabilis jalapa, the four o'clock flower or marvel of Peru, is a Nyctaginaceae perennial native from Mexico to Nicaragua whose fragrant betalain-pigmented flowers open about 4 p.m.; roots and seeds are toxic.
Miracidium
Miracidium (plural miracidia): ciliated, nonfeeding first larval stage of digenean trematodes that hatches from the egg in water, seeks a snail host within roughly 6 to 12 hours, and transforms into a mother sporocyst inside the snail.
Miracle fruit powder
Miracle fruit powder, freeze-dried deseeded Synsepalum dulcificum berry containing miraculin, makes sour foods taste sweet; FDA issued a no-questions GRAS letter (GRN 1144) in January 2024 for use at 0.005% in water-based beverages.
Miracle Mineral Supplement
Miracle Mineral Supplement (MMS, Miracle Mineral Solution) is a 28% sodium chlorite solution promoted by Jim Humble and the Genesis II Church as a cure for malaria, cancer, autism, and COVID-19; mixing with acid yields toxic chlorine dioxide, and regulators warn ingestion is like drinking bleach.
MIRAGE syndrome
MIRAGE syndrome, also called SAMD9-related syndromic adrenal hypoplasia (OMIM 617053), a rare autosomal dominant multisystem disorder from gain-of-function SAMD9 mutations, causing myelodysplasia, infections, growth restriction, adrenal hypoplasia, genital anomalies, and enteropathy.
Miranda Lim
Miranda M. Lim is an American physician-scientist at Oregon Health & Science University and the VA Portland Health Care System who studies how sleep shapes brain health.
miRBase
miRBase is a public reference database of published microRNA sequences and official names, begun in 2002 as the MicroRNA Registry and now the field's de facto nomenclature authority.
Mircea Steriade
Mircea Steriade (1924–2006) was a Romanian-born Canadian systems neuroscientist who spent nearly four decades at Université Laval in Québec City, studying thalamocortical oscillations, sleep spindles, and the cortical slow oscillation.
Mirex
Mirex (CAS 2385-85-5), an organochlorine insecticide and fire retardant used 1959–1978 mainly against fire ants; canceled by EPA, listed as a Stockholm Convention POP, persistent and bioaccumulative, NTP carcinogen.
Miriam H. Meisler
Miriam H. Meisler is an American human geneticist at the University of Michigan who identified the epilepsy genes SCN8A and SCN1A and received the American Epilepsy Society's 2020 Basic Science Research Award.
Miriam J. Alter
Miriam J. Alter is an American epidemiologist who led the CDC's sentinel-county hepatitis surveillance, showed hepatitis C usually becomes chronic, and later worked at the University of Texas Medical Branch.
Miriam M. Salpeter
Miriam M. Salpeter, also published as M. M. Salpeter, was an American neurobiologist at Cornell University who developed quantitative electron-microscope autoradiography to study the neuromuscular junction.
Miriam Menkin
Miriam Menkin, born Miriam Friedman (1901–1992), was a Latvian-born American laboratory researcher who performed the first fertilization of a human egg outside the body in 1944.
Miriam Mérad
Miriam Merad is a Paris-born, Algeria-raised immunologist at the Icahn School of Medicine at Mount Sinai, known for discovering that tissue-resident macrophages arise from embryonic precursors and self-renew locally.
Miriam Rothschild
Dame Miriam Rothschild (1908-2005), British naturalist and entomologist, world authority on fleas, butterflies, and pyrazines; discovered the rabbit flea's hormone-controlled breeding cycle and the flea jumping mechanism; Bletchley Park code breaker; FRS 1985.
Mirikizumab
Mirikizumab (Omvoh, mirikizumab-mrkz), Eli Lilly's humanized IgG4 antibody against IL-23 p19, treats moderate-to-severe ulcerative colitis and Crohn's disease; first approved in Japan in March 2023 and by the FDA in October 2023.
Mirizzi syndrome
Mirizzi syndrome: rare gallstone complication in which a stone impacted in Hartmann's pouch or the cystic duct externally compresses the common bile duct, later forming cholecystobiliary fistulas; classified McSherry/Csendes, hard to diagnose preoperatively.
Mirjam Christ‐Crain
Mirjam Christ-Crain, born 1974, is a Swiss endocrinologist, full professor at the University of Basel, and chief of endocrinology at University Hospital Basel, known for copeptin diagnostics.
Mirko Trajkovski
Mirko Trajkovski is a professor at the University of Geneva's Faculty of Medicine who studies the molecular mechanisms of obesity, insulin resistance, and gut microbiota.