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Life and health

72,234 articles

Dasotraline

Dasotraline (SEP-225289) is an investigational dopamine and norepinephrine reuptake inhibitor developed by Sunovion for ADHD and binge-eating disorder; trials showed efficacy, but its NDAs were withdrawn in 2020 and it was never marketed.

Dasyatidae

Dasyatidae, whiptail stingrays, is a family of Myliobatiformes rays with a rounded disc, whip-like tail, and venomous sting. Revised in 2016 into four subfamilies and 18 genera; primarily marine, circumglobal.

Dasyatis pastinaca

Dasyatis pastinaca, the common stingray or blue stingray, is a whiptail stingray of the eastern Atlantic and Mediterranean, benthic to 200 m, ovoviviparous, venomous-spined, and IUCN Vulnerable.

Dasymutilla klugii

Dasymutilla klugii (Klug's velvet ant), a wingless parasitoid wasp (Mutillidae) of North America and Mexico, rated 3/4 on the Schmidt sting pain index, with peptide venom Dk5a and Dk13a acting on cell membranes.

Dasymutilla occidentalis

Dasymutilla occidentalis, the red velvet ant or cow killer, is an eastern US parasitoid wasp (Mutillidae); wingless females have an extremely painful peptide venom, tough cuticle, stridulation, and aposematic coloration in the Eastern mimicry ring.

Dasypus

Dasypus (long-nosed armadillos), genus Linnaeus 1758, type species D. novemcinctus; most speciose armadillo genus, Argentina to United States, obligatory polyembryony, leprosy host, revised to eight species in 2018.

Dasyuridae

Dasyuridae, the dasyurid marsupials, is the largest family of Australian carnivorous marsupials (order Dasyuromorphia), spanning the 4-gram long-tailed planigale to the Tasmanian devil, with polyprotodont dentition and male semelparity in some genera.

Dat Boi

Dat Boi: 2016 Internet meme of a 3D clip-art green frog on a unicycle, greeted with "here come dat boi" and "o shit waddup"; went viral from Facebook in April 2016, fourth most-Googled meme of 2016, revived on /r/me_irl in 2017.

Data-dependent acquisition

Data-dependent acquisition (DDA) is a mass spectrometry acquisition mode that automatically selects and fragments the most abundant ions from each survey scan, the most common mode in shotgun proteomics.

Data-independent acquisition

Data-independent acquisition (DIA) is a mass spectrometry method for quantitative proteomics in which the instrument fragments all peptide ions in predefined isolation windows, without selecting precursors in real time.

Date palm

Date palm (Phoenix dactylifera), the iconic fruit palm of North Africa and the Middle East, cultivated since 4000 BC; dioecious, over 5,000 cultivars, two gene pools, dates over 3,000 calories/kg.

Datopotamab deruxtecan

Datopotamab deruxtecan (Dato-DXd, DS-1062a, Datroway) is a TROP2-directed antibody-drug conjugate with a DXd topoisomerase I inhibitor payload, approved in the US for EGFR-mutated NSCLC, TNBC, and HR-positive HER2-negative breast cancer, and in the EU for breast cancer.

Datronia

Datronia is a genus of Polyporaceae wood-rot fungi established by Donk in 1966, type species D. mollis; the 2014 multi-gene revision restricted it to two species and segregated Datroniella and Neodatronia.

Datroniella

Datroniella is a small polypore fungus genus (Polyporaceae) split from Datronia in 2014 by Li, Cui, and Dai, typified by D. scutellata; after Zmitrovich's 2018 transfer to Cerioporus, only D. minuta from Brazil remains.

Datura

Datura (thorn-apple, jimsonweed; Sanskrit dhattūra) is a genus of 14 toxic Solanaceae herbs native from the SW and S-central USA to Mexico, naturalized worldwide, containing atropine, hyoscyamine, and scopolamine; distinct from the pendulous-flowered Brugmansia.

Datura metel

Datura metel, also known as devil's trumpet or thorn's apple, is a nightshade herb with large trumpet-shaped flowers, native to Mexico and cultivated worldwide as a narcotic and medicine.

Datura stramonium

Datura stramonium (jimson weed, thorn apple), Solanaceae annual herb native to Mexico, now a pantropical weed; all parts contain tropane alkaloids atropine, hyoscyamine, scopolamine; seeds contaminate grain and cause anticholinergic poisoning.

Daucus

Daucus is a genus of 45 Apiaceae herb species including cultivated carrot (D. carota subsp. sativus) and wild carrot, Queen Anne's lace; domesticated in medieval Central Asia, orange roots selected in Renaissance Europe.

Daucus carota

Daucus carota, wild carrot or Queen Anne's lace, is an Apiaceae biennial native to Europe, southwest Asia, and North Africa and progenitor of cultivated carrot (subsp. sativus), domesticated once in Central Asia with orange carrots later selected in the Netherlands.

Daudi

Daudi (DAUDI, CVCL_0008) is a human Burkitt lymphoma B-lymphoblast cell line established in 1967 by the Kleins from a 16-year-old male; EBV-positive, MYC-IGH fusion, B2M-deficient, HLA class I-negative, standard for interferon assays.

Dauer larva

Dauer larva: the stress-resistant, developmentally arrested dispersal stage of Caenorhabditis elegans and related nematodes, induced by pheromone, starvation, or heat at the L2 molt, controlled by TGF-β, insulin, and DAF-12/dafachronic acid pathways, and living for months.

Daunorubicin resistance protein C

DrrC (daunorubicin resistance protein C) of Streptomyces peucetius, a 764-aa UvrA-like ATP-dependent DNA-binding protein that ejects intercalated daunorubicin from DNA; distinct from the DrrAB efflux pump and from mycobacterial membrane DrrC subunits.

Dave A. Chokshi

Dave A. Chokshi (Dave Ashok Chokshi) is an American physician and health policy researcher who served as New York City's 43rd health commissioner from 2020 to 2022.

Dave Asprey

Dave Asprey (born 1973), American entrepreneur, founder of Bulletproof and Bulletproof Coffee (butter and MCT oil in coffee), self-described father of biohacking; his diet and health claims face repeated scientific and fact-checking criticism.

Dave Goulson

Dave Goulson, British biologist, Professor of Biology at the University of Sussex, founder of the Bumblebee Conservation Trust (2006), author of A Sting in the Tale, and leading researcher on neonicotinoid pesticide effects on bumblebees.

Dave Singh

Dave Singh is a British respiratory physician-scientist, Professor at the University of Manchester since 2011 and Medical Director of the Medicines Evaluation Unit, known for leading major COPD drug trials.

Daved H. Fremont

Daved H. Fremont is a structural biologist and immunologist who is a professor at Washington University in St. Louis, known for defining the structural basis of Zika virus antibody protection.

David A. Agard

David A. Agard is an American structural biologist and biochemist, professor at the University of California, San Francisco, known for Hsp90 chaperone research and advances in cryo-electron microscopy.

David A. Asch

David A. Asch, also known as David Asch, is an American physician and behavioral economist at the University of Pennsylvania who studies how physicians and patients make medical choices.

David A. Barbie

David A. Barbie, also known as David Allen Barbie, is an American medical oncologist and cancer researcher who is Professor of Medicine at Harvard Medical School.