72,234 articles
Darevskia
Darevskia is a genus of small lacertid lizards known as the Caucasian rock lizards, described in 1999, with over 20 species found mainly in the Caucasus and including seven parthenogenetic species.
Darexaban
Darexaban (YM150, darexaban maleate) is an oral direct factor Xa inhibitor developed by Astellas Pharma for VTE prophylaxis, atrial fibrillation, and acute coronary syndrome; its active glucuronide metabolite YM-222714 carries its anticoagulant effect, and development was discontinued in September 2011.
Daria Mochly‐Rosen
Daria Mochly-Rosen is a chemical and systems biologist at Stanford School of Medicine, known for PKC anchoring proteins and ALDH2 activators, who founded SPARK in 2006.
Daridorexant
Daridorexant (Quviviq), dual orexin receptor antagonist (OX1R/OX2R) insomnia drug by Idorsia, approved 2022 in US and EU; 25–50 mg nightly, ~8 h half-life, CYP3A4-metabolized.
Darier disease
Darier disease (Darier-White disease, keratosis follicularis) is a rare autosomal dominant genodermatosis caused by ATP2A2/SERCA2 mutations, producing keratotic papules, nail changes, and neuropsychiatric features, treated symptomatically with retinoids.
Darifenacin
Darifenacin is a selective muscarinic receptor antagonist, sold as Emselex in Europe and Enablex in the United States, and is used to treat symptoms of overactive bladder syndrome.
Dario Alessi
Dario R. Alessi is a biochemist who directs the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee, known for discovering PDK1 and studying LRRK2 in Parkinson's disease.
Dario C. Altieri
Dario C. Altieri is an Italian-born American physician-scientist who discovered the survivin gene and has been President and CEO of The Wistar Institute in Philadelphia since 2015.
Dario DiFrancesco
Dario DiFrancesco is an Italian physiologist who discovered the cardiac "funny current" (If) at Oxford in 1979; his work underpins the heart-rate drug ivabradine and HCN4 channel research.
Dario Giugliano
Dario Giugliano is an Italian researcher in endocrinology, diabetes, and metabolism at the Università della Campania in Naples, best known for the 2004 JAMA Mediterranean-diet trial.
Dario Leister
Dario Leister, born 1967, is a German plant molecular biologist who has held the Chair of Plant Molecular Biology at LMU Munich since 2005, studying photosynthesis regulation.
Dario Neri
Dario Neri, born in Rome in 1963, is an Italian chemist and antibody engineer, a former professor of Biomacromolecules at ETH Zürich and co-founder and CEO of the biotech company Philogen.
Dario Vignali
Dario A. A. Vignali is an immunologist who chairs the Department of Immunology at the University of Pittsburgh and is best known for discovering the inhibitory cytokine IL-35.
Dariush Mozaffarian
Dariush Mozaffarian is a cardiologist and nutritional epidemiologist at Tufts University, where he led the Friedman School of Nutrition Science and Policy as dean from 2014 to 2022.
Dark Adaptation
Dark adaptation is the slow recovery of visual sensitivity in darkness after light bleaches rhodopsin, taking 30–40 minutes, driven by the retinoid cycle, and delayed in AMD, where rod intercept time is a clinical biomarker.
Dark fermentation
Dark fermentation is an anaerobic, light-independent process in which microorganisms degrade organic substrates and release biohydrogen, with organic acids, alcohols, and CO2 as byproducts; it remains at lab and pilot scale.
Dark skin
Dark skin: high constitutive eumelanin pigmentation, the ancestral Homo phenotype, evolved in equatorial Africa mainly to protect folate from UV photolysis; large melanosomes, MC1R purifying selection, reduced vitamin D synthesis at equal UVB dose.
Dark-eyed junco
Dark-eyed junco (Junco hyemalis), also called snowbird, a common North American forest sparrow with about 15 subspecies including Slate-colored and Oregon forms, lumped from up to seven species in the 1980s; population roughly 630 million.
Darkling beetle
Darkling beetle, member of the beetle family Tenebrionidae (about 20,000-30,000 species), including mealworms (Tenebrio molitor) and Namib Desert fog-basking Onymacris; known for desert water-conservation adaptations and stored-grain pests.
Darolutamide
Darolutamide (Nubeqa, ODM-201) is an oral androgen receptor inhibitor by Bayer for prostate cancer, approved 2019 (US) and 2020 (EU), with low brain penetration, few drug interactions, and favorable tolerability versus enzalutamide and apalutamide.
Darrel W. Stafford
Darrel W. Stafford is a Professor Emeritus of biology at the University of North Carolina at Chapel Hill who identified the gene for vitamin K epoxide reductase.
Darrell H. Carney
Darrell H. Carney is a biochemist, adjunct professor at the University of Texas Medical Branch, and founder of Chrysalis BioTherapeutics, known for developing the tissue-repair peptide TP508.
Darrell J. Irvine
Darrell J. Irvine is a bioengineer and immunologist, Professor and Vice Chair of Immunology & Microbiology at Scripps Research and an HHMI Investigator since 2008, known for engineering vaccine delivery.
Darrell N. Kotton
Darrell N. Kotton is a pulmonary physician-scientist at Boston University who founded its Center for Regenerative Medicine and pioneered methods for generating lung cells from patients' stem cells.
Darren K. McGuire
Darren K. McGuire is an American cardiologist and clinical trialist at UT Southwestern Medical Center in Dallas, known for leading major diabetes drug cardiovascular outcome trials.
Darrin M. York
Darrin M. York is an American computational chemist, Distinguished Professor at Rutgers University, known for computing ribozyme catalytic mechanisms and co-developing the Amber simulation software.
Darryl C. De Vivo
Darryl C. De Vivo is an American child neurologist and neurometabolic physician-scientist, Sidney Carter Professor Emeritus at Columbia University, known for identifying Glut1 deficiency syndrome and co-authoring the 2017 nusinersen trial.
Darryl C. Zeldin
Darryl C. Zeldin is an American physician-scientist and Scientific Director of the National Institute of Environmental Health Sciences, known for research on cytochrome P450 enzymes and national allergy epidemiology.
DARS1
DARS1 (DARS, HBSL, aspRS; HGNC:2678, MIM 603084) is the human cytoplasmic aspartyl-tRNA synthetase gene at 2q21.3; biallelic missense mutations cause the leukodystrophy HBSL (OMIM 615281).
Dartmoor pony
Dartmoor pony, native British pony breed of Dartmoor, Devon, also called Dartmoor Hill Pony in semi-wild form. Max 127 cm (12.2 hh), 250-350 kg; RBST 'At Risk' rare breed; about 900-1,500 graze the moor, protected by 2026 government measures.