72,234 articles
Digestive system fistula
Digestive system fistula (ICD-11 ME24.1): an abnormal epithelial connection between the GI tract and another organ or the skin. Mostly acquired from surgery, Crohn's disease, diverticulitis, cancer, or radiation; 20–37% of enterocutaneous fistulas close spontaneously.
Digestive system of bivalves
The digestive system of bivalves is the alimentary tract built around a rotating crystalline style, with a stomach, digestive gland, and intestine that complete digestion intracellularly.
Digestive system of gastropods
Digestive system of gastropods: the snail and slug gut, mouth to anus, with radula, salivary glands and digestive gland; torsion makes the gut U-shaped, and organization varies with herbivory, carnivory, or parasitism.
Digestive System Surgical Procedures
Digestive system surgical procedures (MeSH E04.210): operations on the gastrointestinal tract, liver, biliary tract, and pancreas, performed open, laparoscopically, or robot-assisted, with ERAS perioperative care protocols.
Digit ratio
Digit ratio (2D:4D) is index finger length divided by ring finger length; lower in males, proposed in 1998 as a prenatal testosterone marker, though large meta-analyses find weak hormone validation.
Digit symbol substitution test
The digit symbol substitution test (DSST) is a timed neuropsychological test of processing speed, in which a person copies geometric symbols beneath matching digits using a key.
Digital breast tomosynthesis
Digital breast tomosynthesis (DBT) is an X-ray technique that reconstructs low-dose breast projections into thin slices, revealing lesions hidden by overlapping tissue in 2D mammograms.
Digital contact tracing
Digital contact tracing is a public health surveillance method that uses smartphone apps, mostly Bluetooth-based, to notify people exposed to an infectious disease so they can test and isolate.
Digital ELISA
The single-molecule array (Simoa) is a digital ELISA technology commercialized by Quanterix that counts individual enzyme-labeled protein complexes in femtoliter wells, roughly 1,000-fold more sensitive than conventional immunoassays.
Digital Health
Digital health is the use of digital technologies to improve health, an umbrella term the World Health Organization applies to eHealth, mHealth, telemedicine, big data, genomics, and artificial intelligence.
Digital PCR
Digital PCR (dPCR) is a nucleic acid quantification method that splits a PCR reaction into many partitions and counts target molecules absolutely, without a calibration curve.
Digital radiography
Digital radiography (DR) is a medical imaging method that captures X-ray images with electronic detectors instead of screen-film cassettes, producing digital radiographs that can be processed, stored, and displayed electronically.
Digital smile design
Digital smile design (DSD) is a digital dentistry workflow that uses facial and intraoral photographs, video, and software to analyze smile esthetics and plan cosmetic treatment, producing a digital wax-up and mock-up.
Digital spatial profiling
Digital spatial profiling (DSP) is a spatial omics method that quantifies dozens to thousands of proteins or transcripts in selected regions of tissue sections, commercialized as GeoMx and reported in 2020.
Digital subtraction angiography
Digital subtraction angiography (DSA): fluoroscopic X-ray technique subtracting a pre-contrast mask image from contrast-filled frames to show vessels; gold standard in neurovascular imaging since 1980.
Digitalis
Digitalis (foxglove), Plantaginaceae genus and cardiac glycoside drug; source of digoxin and digitoxin, Na+/K+-ATPase inhibitors introduced by Withering's 1785 Account of the Foxglove for dropsy and heart failure.
Digitalis lanata
Digitalis lanata (woolly or Grecian foxglove), Plantaginaceae, a biennial/perennial herb native from SE Europe to NW Türkiye, cultivated for digoxin and lanatosides; introduced and weedy in North America.
Digitalis poisoning
Digitalis poisoning, or digoxin toxicity, is poisoning by cardiac glycosides causing GI, neurologic, visual, and cardiac symptoms. Treated with digoxin immune Fab; dialysis is not indicated; mortality around 13-14%.
Digitalis purpurea
Digitalis purpurea, common foxglove, is a biennial European plant with purple tubular flowers, source of cardiac glycosides like digitoxin, codified by Withering in 1785, and toxic in all parts.
Digitaria
Digitaria (crabgrasses), a cosmopolitan Poaceae genus of about 250-267 species published by Haller in 1768; includes lawn weeds D. sanguinalis and D. ischaemum and the West African cereal fonio, Digitaria exilis.
Digitaria sanguinalis
Digitaria sanguinalis, large or hairy crabgrass, is an annual C4 grass native from the Mediterranean to Central Asia and Malesia, now a major global weed of crops, lawns, and turf with documented herbicide resistance.
Diglyceride
A diglyceride, more precisely a diacylglycerol (DAG), is a glyceride with two fatty acids esterified to glycerol, serving as a membrane component, lipid precursor, and second messenger.
Diglyceride acyltransferase
Diglyceride acyltransferase (DGAT, EC 2.3.1.20) catalyzes the final step of triglyceride synthesis. Two unrelated enzymes, DGAT1 (MBOAT family) and DGAT2, have non-redundant roles, distinct knockout phenotypes, and clinical and crop-oil relevance.
Dignity of risk
Dignity of risk, also called the right to take reasonable risks, is a care ethics principle coined by Robert Perske in 1972 for people with intellectual disabilities, now embedded in disability and aged care law including Australia's Aged Care Act 2024.
Dignity therapy
Dignity therapy is a brief psychotherapy for patients with advanced illness, in which a recorded life-story interview is edited into a legacy document to bequeath to loved ones.
Digoxin
Digoxin, a cardiac glycoside from Digitalis lanata, treats mild to moderate heart failure and controls ventricular rate in chronic atrial fibrillation; neutral mortality in trials, narrow therapeutic window.
Digoxin toxicity
Digoxin toxicity, also called digitalis intoxication, is poisoning by the cardiac glycoside digoxin, marked by GI, visual, and cardiac symptoms, hyperkalemia, and arrhythmias; treated with digoxin immune Fab (DigiBind, DigiFab).
DIGS study
The Diagnostic Innovations in Glaucoma Study (DIGS) is a longitudinal cohort study at the University of California, San Diego, running since 1995 to find the best methods for detecting glaucoma progression.
Diguanylate cyclase Dgc-like, bacteria
Diguanylate cyclase (DGC, Dgc-like, GGDEF domain) enzymes in bacteria synthesize the second messenger c-di-GMP from two GTP molecules as homodimers, regulating biofilm formation, motility, and virulence; balanced by EAL and HD-GYP phosphodiesterases.
Dihua Yu
Dihua Yu is a cancer biologist at MD Anderson Cancer Center, where she chairs Molecular Oncology and studies breast and pancreatic cancer metastasis and therapy resistance.