edgepedia

Life and health

72,234 articles

Ectropion of eyelid

Ectropion of the eyelid: outward turning of the eyelid margin, usually the lower lid, exposing the inner surface. Main types involutional, cicatricial, mechanical, paralytic; treated with lubricants and lateral tarsal strip surgery.

Ecuadorian hermit crab

The Ecuadorian hermit crab, also known as Coenobita compressus, is a semi-terrestrial land hermit crab living on sandy Pacific beaches from southern Mexico to Ecuador and northern Peru.

Eculizumab

Eculizumab (Soliris) is a humanized anti-C5 monoclonal antibody, the first approved complement inhibitor (FDA 2007), treating PNH, aHUS, gMG, and NMOSD; it blocks C5 cleavage to C5a/C5b, requires meningococcal vaccination, and has biosimilars Epysqli and Bkemv.

ECV trial

ECV trial (NCT04346823), Sevoflurane and Success of External Cephalic Version: a phase 4 randomized trial by King Saud University testing 1% inhaled sevoflurane versus no intervention to raise ECV success in 40 women at 36-40 weeks.

ECV-304

ECV-304 (CVCL_2029), a human cell line described in 1990 as spontaneously transformed umbilical vein endothelial cells but shown in 1999 to be a T24 bladder carcinoma derivative; ICLAC-00117, still used in endothelial and vasculogenic mimicry studies.

ECWP herbarium

ECWP herbarium, Emirates Centre for Wildlife Propagation herbarium in Missour, Morocco, indexed in Index Herbariorum since 2000; holds 2,450 Moroccan taxa including type specimens, supporting houbara bustard habitat research in eastern Morocco.

Eczema Area and Severity Index

The Eczema Area and Severity Index (EASI) is a clinical scoring tool for atopic dermatitis, grading lesion extent and severity across body regions on a 0 to 72 scale.

Ed Diener

Ed Diener, known as "Dr. Happiness," was an American psychologist (1946–2021) who founded the scientific study of subjective well-being, working mostly at the University of Illinois Urbana-Champaign.

Ed Harlow

Ed Harlow is an American molecular biologist at Harvard Medical School whose 1988 Nature paper showed the adenovirus E1A protein physically binds the retinoblastoma gene product.

Ed Hurt

Ed Hurt (Eduard Christian Hurt, born 1955) is a molecular biologist and professor at Heidelberg University's Biochemistry Center, known for work on ribosome assembly and mRNA export.

Ed Palmer

Ed Palmer is a Swiss-based immunologist and emeritus professor at the University of Basel, known for work on how the T cell receptor selects self-reactive T cells in the thymus.

Ed S. Lein

Ed S. Lein is a neuroscientist at the Allen Institute in Seattle who builds cellular and gene-expression atlases of the mammalian brain and co-leads the NIH BICAN human brain atlas project.

EDA

EDA (ectodysplasin A, HGNC:3157) is an Xq13.1 gene encoding a TNF-family ligand; its furin-cleaved isoform EDA-A1 binds EDAR, and mutations cause X-linked hypohidrotic ectodermal dysplasia and nonsyndromic tooth agenesis.

Edamame (枝豆)

Edamame (枝豆, maodou) is immature vegetable soybean harvested at R6-R7 when beans fill 80-90% of the pod; boiled and salted, rich in protein, with a 7-10 day harvest window and 3-10 hour postharvest sugar decline.

Edaravone (エダラボン)

Edaravone (エダラボン; Radicut/Radicava) is a free-radical scavenging drug approved in Japan (2001) for acute ischemic stroke and in the US (2017 IV, 2022 oral) to slow decline in ALS, one of three FDA-approved ALS drugs.

Edaravone and dexborneol concentrated solution for injection

Edaravone dexborneol concentrated solution for injection (依达拉奉右莰醇注射用浓溶液, Xianbixin) is a Simcere 4:1 edaravone/(+)-dexborneol neuroprotectant, 37.5 mg twice daily for 10-14 days, approved in China for acute ischemic stroke; TASTE and TASTE-2 trials support functional benefit.

Edasalonexent

Edasalonexent (CAT-1004), an oral NF-κB inhibitor conjugating salicylic acid and DHA, was Catabasis Pharmaceuticals' experimental therapy for Duchenne muscular dystrophy; development ended in 2020 after the phase 3 PolarisDMD trial missed its endpoints.

Edema

Edema (oedema, dropsy) is soft-tissue swelling from excess interstitial fluid, caused by raised capillary pressure, low plasma oncotic pressure, capillary leak, or lymphatic obstruction; common causes are heart, liver, and kidney disease, DVT, and medications.

Edetate calcium disodium anhydrous

Edetate calcium disodium anhydrous (calcium disodium EDTA, CaNa2EDTA, CAS 62-33-9) is a chelating drug approved in 1953 for lead poisoning, distinct from edetate disodium, and also a food and cosmetic sequestrant.

Edgar Adrian

Edgar Adrian, also Edgar Douglas Adrian, was a British electrophysiologist who showed that nerves encode stimulus strength by firing frequency, sharing the 1932 Nobel Prize in Physiology or Medicine.

Edgar Allen

Edgar Allen (1892–1943) was a reproductive physiologist at Washington University School of Medicine who, with Edward A. Doisy, isolated estrogen in 1923.

Edgar Anderson

Edgar Anderson (1897–1969) was an American botanist and geneticist at the Missouri Botanical Garden, best known for naming introgressive hybridization, the transfer of genes between species.

Edgar B. Jackson Jr.

Edgar B. Jackson Jr. was an American internist who became the first African American chief of staff at a major academic medical center, at Cleveland's University Hospitals in 1997.

Edgar G. Engleman

Edgar G. Engleman is an American immunologist and Stanford professor of pathology and medicine who founded the Stanford Blood Center and pioneered human dendritic-cell cancer immunotherapy.

Edgar Haber

Edgar Haber (1932–1997) was a German-born research physician who led the Cardiac Unit at Massachusetts General Hospital from 1964 to 1988 and developed a worldwide digoxin diagnostic test.

Edgar Lederer

Edgar Lederer (1908–1988) was a French biochemist of Austrian origin who revived chromatography in 1931 and spent decades studying carotenoids and mycobacterial lipids, including mycolic acids.

Edgar S. Cathcart

Edgar S. Cathcart (died 2008) was a rheumatologist known internationally for his amyloid protein research, and professor of medicine at Boston University from 1977 to 2003.

Ediacaran biota

Ediacaran biota (Ediacara biota), the assemblage of large soft-bodied marine organisms of 575–542 Ma, first large complex life, preserved as casts and molds; includes Dickinsonia, Rangea, Charniodiscus; vanished near the Cambrian boundary.

Edibility assessment and lookalike discrimination of wild mushrooms

Edibility assessment of wild mushrooms: deciding if a foraged fungus is safe to eat and separating edible species from toxic lookalikes like the death cap; no rule of thumb exists, cooking does not detoxify, and AI apps misidentify most specimens.

Edible frog

Edible frog (Pelophylax esculentus, formerly Rana esculenta) is a European hybridogenetic hybrid of the pool frog and marsh frog, reproducing via clonal genome transmission in L-E, R-E, and all-hybrid populations.