72,234 articles
Eleutheronema tetradactylum
Eleutheronema tetradactylum, the fourfinger threadfin or Indian salmon, is an Indo-West Pacific polynemid fish with four pectoral filaments, protandrous hermaphroditism, high commercial value in fisheries and aquaculture, and a 2025 near-telomere-to-telomere genome assembly.
ELEVATE trial
ELEVATE trial (NCT04340349), a Mexican randomized double-blind placebo-controlled Early Phase 1 trial testing hydroxychloroquine 200 mg/day plus bromhexine 8 mg/8h for 60 days to prevent SARS-CoV-2 infection in healthcare workers; no results posted.
ELEVATE UC 12 trial
ELEVATE UC 12 (NCT03996369, APD334-302) was Arena Pharmaceuticals' phase 3, double-blind trial of etrasimod 2 mg daily vs placebo for 12-week induction in moderate-to-severe ulcerative colitis; 354 randomized, remission 24.8% vs 15.2%.
ELEVATE UC 52 trial
ELEVATE UC 52 (NCT03945188), phase 3 trial of etrasimod 2 mg daily for ulcerative colitis; 12-week induction plus 40-week maintenance, 433 randomized, supporting 2023 FDA approval of Velsipity.
Elevated alkaline phosphatase
Elevated alkaline phosphatase (raised ALP, hyperphosphatasemia): serum elevation of a multi-tissue ectoenzyme, usually from bone (osteoblastic disease) or liver (cholestasis), also placenta and intestine; evaluated by GGT and isoenzyme fractionation.
Elevated blood glucose level
Elevated blood glucose level, or hyperglycemia, is excessive blood glucose, classified in ICD-11 as MA18.0. It spans prediabetes (FPG 100–125 mg/dL) to diabetes (FPG ≥126 mg/dL, A1C ≥6.5%) and causes DKA and hyperosmolar state.
Elevated C-reactive protein
Elevated C-reactive protein (raised CRP, hs-CRP elevation; ICD-11 MA14.15) is a nonspecific blood marker of inflammation from infection, trauma, or chronic disease; normal below 0.3 mg/dL, marked above 10 mg/dL.
Elevated erythrocyte sedimentation rate
Elevated erythrocyte sedimentation rate (ESR, sed rate, Westergren sedimentation rate): red cells settle faster than normal in one hour, a nonspecific marker of inflammation; ICD-11 MA1A.0.
Elevated mood
Elevated mood (ICD-11 MB24.8, 高揚気分) is a symptom of persistently elated or expansive mood, coded under mood/affect signs; pathological when persistent and impairing, it is the entry feature of manic episodes in bipolar I disorder.
Elevated transaminases
Elevated transaminases (hypertransaminasemia): raised serum ALT and AST, found in about 10-20% of people. Main causes are fatty liver disease and alcohol; AST/ALT ratio over 2 suggests alcohol-related injury, under 1 NAFLD.
Elexacaftor
Elexacaftor (VX-445) is a CFTR corrector used with tezacaftor and ivacaftor as Trikafta/Kaftrio for cystic fibrosis; FDA-approved 2019, binds TMD1/TMD2 site, boxed liver-injury warning.
ELF3
ELF3 (ESE-1, ESX, ERT, EPR-1), E74 like ETS transcription factor 3 at 1q32.1, is an epithelium-specific ETS transcription factor regulating differentiation, EMT, inflammation, and cancers, acting as tumor suppressor or oncogene by context.
Elfetabart drozuntecan
DB-1311 (BNT324, elfetabart drozuntecan) is a DualityBio-discovered, BioNTech-partnered antibody-drug conjugate targeting B7-H3 with a topoisomerase-I inhibitor payload P1021, in phase 3 development for metastatic castration-resistant prostate cancer.
Eli A. Friedman
Eli A. Friedman is an American nephrologist at SUNY Downstate in Brooklyn, known for the first federally funded US dialysis clinic and the portable "suitcase kidney."
Eli Canaani
Eli Canaani is an Israeli molecular biologist and emeritus professor at the Weizmann Institute of Science, known for identifying the BCR-ABL fusion gene behind chronic myelogenous leukemia.
Eli E. Sercarz
Eli E. Sercarz (1934–2009) was an American immunologist at UCLA known for work on how T cells choose protein targets, introducing dominant and cryptic epitopes and determinant spreading.
Eli Gilboa
Eli Gilboa is an immunologist at the University of Miami known for early gene therapy vectors and mRNA dendritic cell vaccines, a precursor of COVID-19 mRNA vaccines.
Eli Kennerly Marshall Jr.
Eli Kennerly Marshall Jr. (1889–1966) was an American pharmacologist at Johns Hopkins who proved kidney tubules actively secrete substances and pioneered blood-level dosing of sulfonamide drugs.
Eli Keshet
Eli Keshet (born 1945) is an Israeli molecular biologist at the Hebrew University of Jerusalem, known for work on VEGF and how oxygen controls blood vessel growth; he won the 2018 Israel Prize.
Eli Lilly and Company
Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, founded by Colonel Eli Lilly in 1876. It brought the first commercial insulin to market in 1923.
Eli M. Miloslavsky
Eli M. Miloslavsky is an American rheumatologist at Massachusetts General Hospital and Associate Professor at Harvard Medical School, known for research on ANCA-associated vasculitis and glucocorticoid toxicity.
Eli Robins
Eli Robins (1921–1994) was an American psychiatrist and neurochemist at Washington University in St. Louis who co-developed the Feighner Criteria that led to DSM-III and established the psychological autopsy.
Eli Sprecher
Eli Sprecher (born 1963) is an Israeli dermatologist and medical geneticist who has been CEO of Tel Aviv Sourasky Medical Center since 2024 and studies the genes behind inherited skin diseases.
Eli Y. Adashi
Eli Y. Adashi, born 1945 in Haifa, is a reproductive-medicine physician-scientist at Brown University and its former dean of medicine, elected to the National Academy of Medicine in 1999.
Éliane Gluckman
Éliane Gluckman is a French hematologist who performed the first successful umbilical cord blood transplant in 1988 at Hôpital Saint-Louis in Paris and founded Eurocord.
Elias Campo
Elías Campo Güerri is a Spanish hematopathologist, professor at the University of Barcelona, who co-led the first whole-genome sequencing of chronic lymphocytic leukemia and mantle cell lymphoma.
Elias Lazarides
Elias Lazarides is a cell biologist at Caltech known for naming the intermediate filament protein desmin in 1976 and extending the red blood cell membrane skeleton to non-erythroid cells.
Elías Mossialos
Elias Mossialos is a health policy scholar and health economist who holds the Cheng Yu Tung Chair in Global Health at LSE and directs LSE Health.
Elias Schwartz
Elias Schwartz was an American pediatric hematologist who led hematology and served as Physician-in-Chief at Children's Hospital of Philadelphia, and defined beta thalassemia's silent carrier state in 1969.
Elias Zerhouni
Elias Zerhouni is an Algerian-born radiologist and biomedical engineer who served as the 15th Director of the US National Institutes of Health from 2002 to 2008, appointed by President George W. Bush.