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Life and health

72,234 articles

Family Health

Family health: the health status of the family as a unit, including how one member's health and family organization affect members' health; a MeSH concept, nursing field, and measurable household property.

Family medicine

Family medicine, also known as family practice or general practice, is the medical specialty providing first-contact, continuous care for patients of all ages, recognized in the US in 1969.

Family Physicians

Family physicians: specialists in family medicine providing first-contact, continuous, comprehensive lifelong care; certified via the American Board of Family Medicine since 1969; represented by the AAFP.

Family planning

Family planning: attaining desired number and spacing of children via contraception and infertility treatment. Key figures: 164 million unmet need (WHO), 259 million (UNFPA 2024), method failure rates, ICPD 1994 policy shift.

Family planning in India

Family planning in India: the world's first national family planning programme (1952), run by MoHFW under NPP 2000 and NHP 2017; TFR 2.0, mCPR 56.5%, unmet need 9.4%, sterilization-dominated method mix, Mission Parivar Vikas, and the 1975-77 Emergency campaign legacy.

Family Planning Policy

Family planning policy: government laws, guidelines, and programs governing contraceptive access and reproductive choice, from India's 1952 national policy and the 1994 Cairo ICPD rights framework to coercion safeguards and UNFPA's 2022–2030 strategy.

Family Planning Services

Family planning services: organized health services for contraceptive counseling, provision, and infertility care. Key facts: 874 million modern contraceptive users, 164 million unmet need; US Title X (1970) and Medicaid; 1.3 million US unintended pregnancies prevented annually.

Family therapy

Family therapy (systemic therapy) is psychotherapy treating the family unit's relationships and patterns rather than an individual alone. Approaches include structural, Bowen, and multiple family therapy; evidence supports family-based treatment for adolescent eating disorders and family-focused therapy in schizophrenia.

Family Y DNA polymerase

Y-family DNA polymerases (Pol eta, iota, kappa, Rev1) are error-prone translesion synthesis enzymes that bypass DNA damage; POLH defects cause xeroderma pigmentosum-variant skin cancer.

Famine

Famine: the most severe acute food insecurity, defined by the IPC (Phase 5) with thresholds of 20% households starving, 30% child malnutrition, and excess deaths; driven mainly by conflict and government decisions.

Famitinib

Famitinib (SHR1020, Abit), a HengRui sunitinib-analogue multi-targeted TKI inhibiting c-Kit, VEGFR-2/3, PDGFR, FLT3, Ret; approved in China May 2025 with camrelizumab for cervical cancer.

Famotidine

Famotidine (Pepcid, Gaster) is a guanidinothiazole histamine H2 receptor antagonist developed by Yamanouchi and Merck, FDA-approved 1986, about 20 times more potent than cimetidine, used for ulcers, GERD, and hypersecretory conditions.

Famoxadone

Famoxadone (Famoxate, Tanos) is a DuPont oxazolidinedione agricultural fungicide, CAS 131807-57-3, inhibiting fungal mitochondrial complex III (FRAC 11 QoI); EU-banned in 2021 but still registered in the US, Canada, and Australia.

FAMPISEP trial

FAMPISEP (NCT02849782) is a completed phase 4, single-center, open-label trial at the University Hospital of Besançon (2014-2019, 89 participants) testing fampridine 10 mg twice daily in multiple sclerosis, assessing cognitive and gait outcomes.

Fan Wang (neuroscientist)

Fan Wang is a neuroscientist, MIT professor, and McGovern Institute investigator who studies brain circuits of touch, pain, and anesthesia, elected to the National Academy of Sciences in 2026.

FANCA

FANCA (FA complementation group A) is a human gene on chromosome 16 encoding the largest protein of the FA core complex, which repairs DNA interstrand cross-links; its variants cause 60-70% of Fanconi anemia cases and are targets of gene therapy.

FANCC

FANCC (FACC, FA complementation group C) is a human gene on chromosome 9q22.32 encoding a subunit of the FA core complex that monoubiquitinates FANCD2/FANCI for interstrand crosslink repair; biallelic variants cause about 15% of Fanconi anemia cases.

FANCG

FANCG, also called XRCC9, is a human gene on 9p13 encoding a 622-amino-acid FA core complex protein; biallelic variants cause Fanconi anemia complementation group G, about 10% of cases.

FANCI

FANCI (FA complementation group I, KIAA1794) is a human gene at 15q26.1 encoding the FANCI DNA repair protein, which heterodimerizes with FANCD2 as the ID clamp of the Fanconi anemia interstrand cross-link repair pathway; biallelic variants cause Fanconi anemia.

Fanconi anemia

Fanconi anemia (FA), also called Fanconi pancytopenia, is a rare inherited DNA repair disorder causing bone marrow failure, congenital abnormalities, and high leukemia and solid tumor risk; treated by HSCT, with gene therapy trials for FANCA subtype.

Fanconi anemia group E protein

FANCE (UniProt Q9HB96), the Fanconi anemia group E protein, is a 536-amino-acid human FA core complex subunit in the CEF module; it stabilizes FANCC, adapts FANCD2 as ubiquitination substrate via Phe-522, and causes FA complementation group E when mutated.

Fanconi anemia group F protein

FANCF, Fanconi anemia group F protein, is a 374-aa nuclear adaptor in the FA core complex (C-E-F subcomplex, binds FANCG/FANCA/FANCC, links FANCM), enabling FANCD2 monoubiquitination and interstrand crosslink repair; FANCF mutations cause FA group F (~2% of patients).

Fanconi Anemia Pathway

Fanconi anemia (FA) pathway, also called the FA-BRCA pathway: a DNA repair pathway for interstrand crosslinks, activated by FANCL/UBE2T monoubiquitination of FANCD2-FANCI and coordinating nucleases, translesion synthesis, and homologous recombination.

Fanconi syndrome

Fanconi syndrome: generalized proximal renal tubule reabsorption failure causing glucosuria, aminoaciduria, phosphaturia, and bicarbonate wasting; hereditary (cystinosis most common) or acquired (drugs, heavy metals); distinct from Fanconi anemia.

Fanconi-Bickel syndrome

Fanconi-Bickel syndrome (FBS), formerly glycogen storage disease XI, is a rare autosomal recessive disorder caused by SLC2A2 mutations, marked by hepatomegaly, short stature, rickets, and renal tubular dysfunction.

Fancy rat

Fancy rat: domesticated brown rat (Rattus norvegicus) kept as pet or show animal. First bred in Edo Japan (1603–1868), then Victorian England via rat-baiting; Mary Douglas founded the rat fancy; varieties include dumbo, rex, satin.

Fang Fang

Fang Fang is a Swedish-based neuroepidemiologist and professor of epidemiology at Karolinska Institutet in Stockholm, known for research on suicide after cancer diagnosis and ALS risk factors.

Fang Huang (molecular biologist)

Fang Huang is a Chinese-American biophysicist and Reilly Professor of Biomedical Engineering at Purdue University, known for whole-cell 4Pi nanoscopy and imaging methods reaching nanoscale resolution deep inside tissues.

Fang‐Jie Zhao

Fang-Jie Zhao (赵方杰) is a Chinese plant nutrition researcher, a professor at Nanjing Agricultural University since 2012 after twenty years at Rothamsted Research, known for discovering how arsenic enters rice.

Fangji Fuling Tang

Fangji Fuling tang (防己茯苓汤) is a five-herb classical Chinese formula first recorded in Zhang Zhongjing's Jin Gui Yao Lue, known for warming yang and promoting diuresis.