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Life and health

72,234 articles

Faropenem

Faropenem (Farom) is a synthetic oral penem beta-lactam antibiotic, first marketed in Japan in 1997, approved also in India, with broad-spectrum activity, high beta-lactamase stability, and WHO reserve classification.

Farren J. Isaacs

Farren J. Isaacs is a synthetic biologist and genome engineer, professor at Yale, known for building genomically recoded bacteria and the MAGE and CAGE engineering tools.

Farrier

Farrier: a professional who trims, balances, and shoes horses' hooves, combining blacksmithing with equine foot anatomy. UK-regulated under the Farriers (Registration) Act 1975; four-year apprenticeship; elsewhere accredited by bodies such as the IAPF.

Farro

Farro is an Italian term for grains of three hulled wheat species, einkorn, emmer, and spelt; in Italy it especially means emmer, the "true" farro.

Fart lighting

Fart lighting, or pyroflatulence, is igniting flatus to produce a brief blue flame from gut-produced hydrogen and methane. Feasible only when gas concentrations exceed flammability limits; causes burn injuries and is a surgical hazard.

Fart walk

A fart walk, also called postprandial walking, is a casual walk taken shortly after eating, popularized by Canadian cookbook author Mairlyn Smith in a viral 2024 TikTok video.

Fas ligand

Fas ligand (FasL, CD95L, CD178, FASLG) is a 40 kDa type II transmembrane TNF-family ligand binding Fas/CD95; membrane-bound form drives apoptosis, inflammation, and immune privilege, while shed soluble FasL is largely antagonistic.

Fas receptor

FAS (CD95, APO-1, TNFRSF6), Fas cell surface death receptor gene at 10q23.31, encodes a TNF-receptor-family death receptor driving FADD/caspase-8 DISC apoptosis; germline variants cause ALPS-FAS and lymphoma risk.

FAS1 domain

FAS1 (fasciclin 1) domain: an ancient ~140-amino-acid extracellular cell adhesion module found in bacteria, plants, and animals; defines plant FLA proteins and includes human TGFBI and periostin, whose mutations cause corneal dystrophies.

Fascia

Fascia is a sheet or band of collagen-rich connective tissue beneath the skin that attaches, encloses, and separates muscles and organs, divided into superficial, deep, parietal, and visceral types.

Fascia iliaca compartment block

The fascia iliaca compartment block, or fascia iliaca block, is a regional anesthesia technique used mainly for pain control in hip fracture and hip and knee surgery.

Fascial plane block

A fascial plane block is a regional anesthesia technique injecting local anesthetic between fascial layers to numb multiple nerves, used in abdominal, chest, and breast surgery.

Fasciation

Fasciation is a plant malformation in which the growing tip produces flattened, often twisted shoots that look like several stems fused, a growth sometimes described as crested.

Fasciculation

Fasciculation, also called muscle twitching or benign fasciculation when isolated, is an involuntary visible contraction of one motor unit arising from the lower motor neuron; common in healthy people, a sign of ALS when paired with weakness, and part of the peripheral nerve hyperexcitability spectrum.

Fasciectomy

Fasciectomy is a surgical procedure that removes diseased fascia, performed most often to straighten fingers bent by Dupuytren's contracture; open partial fasciectomy is the mainstay treatment.

Fasciitis or fibromatosis

Fasciitis or fibromatosis (FB51.2) is an ICD-11 fibroblastic disorders code covering nodular fasciitis, also called pseudosarcomatous fibromatosis, a rare benign rapidly growing subcutaneous soft tissue tumor.

Fascin

Fascin (FSCN1), a 55 kDa globular monomeric actin-bundling protein with four β-trefoil domains, cross-links actin into tight ~8 nm-spaced parallel bundles in filopodia; overexpressed in metastatic cancer, targeted by phase 2 inhibitors.

Fasciola

Fasciola: genus of liver fluke trematodes; species F. hepatica and F. gigantica infect sheep, cattle, and humans via watercress and lymnaeid snails, causing fascioliasis, a WHO neglected tropical disease.

Fasciola hepatica

Fasciola hepatica, the common or sheep liver fluke, is a large trematode of ruminant bile ducts that also causes human fascioliasis via watercress-borne metacercariae; treated with triclabendazole, found in over 70 countries.

Fasciolariidae

Fasciolariidae, the tulip, spindle, and horse conch snails (Gray, 1853), is a monophyletic neogastropod family of over 500 predatory marine species with Cretaceous origins, fusiform shells, and non-drilling predation on other mollusks.

Fascioliasis

Fascioliasis, liver fluke disease caused by Fasciola hepatica and F. gigantica, a foodborne zoonotic neglected tropical disease spread by raw watercress and contaminated water, treated with triclabendazole.

Fasciolidae

Fasciolidae, the liver fluke family of digenean trematodes including Fasciola hepatica, F. gigantica, and Fasciolopsis buski; parasites of mammalian livers and intestines causing fascioliasis, a WHO neglected tropical disease.

Fasciotomy

Fasciotomy is an emergency surgical procedure that cuts the fascia enclosing a muscle compartment to lower pressure and restore blood flow, the only recognized treatment for acute compartment syndrome.

Fasedienol

Fasedienol (PH94B, Aloradine) is Vistagen's investigational intranasal pherine spray for acute treatment of social anxiety disorder; one positive Phase 3 (PALISADE-2) but three failed primary-endpoint trials.

Fasiglifam

Fasiglifam (TAK-875) is a Takeda GPR40/FFAR1 partial agonist for type 2 diabetes that lowered HbA1c with low hypoglycemia risk but was terminated in December 2013 during phase III trials due to drug-induced liver injury.

Fasiha Kanwal

Fasiha Kanwal is a physician-scientist and tenured professor of medicine at Baylor College of Medicine in Houston, known for VA cohort research on liver cancer risk in hepatitis C.

Fasinumab

Fasinumab (REGN475, SAR164877, MT-5547) is a fully human IgG4 anti-nerve growth factor monoclonal antibody developed by Regeneron with Teva and MTPC for osteoarthritis and chronic low back pain; effective in phase 3 trials but discontinued in 2022 over dose-dependent joint damage risk.

FAST (stroke)

FAST (Face, Arms, Speech, Time) is a mnemonic teaching laypeople to spot stroke signs and call an ambulance, developed in 1998 in Newcastle and extended as BE-FAST.

Fast Healthcare Interoperability Resources

Fast Healthcare Interoperability Resources (FHIR, "fire") is HL7's open API-based standard for exchanging health data via modular resources and RESTful interfaces. First presented 2012; R5 (2023) has 157 resource types; FHIR R4 is mandated for US ONC certification.

Fast photochemical oxidation of proteins

Fast photochemical oxidation of proteins (FPOP) is a protein footprinting method that uses laser-generated hydroxyl radicals and mass spectrometry to measure protein structure in solution, introduced by Hambly and Gross in 2005.