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Fátima Cardoso
Fátima Cardoso is a Portuguese medical oncologist specializing in breast cancer, known for leading the MINDACT trial and creating Portugal's first certified Breast Unit in Lisbon.
Fatima Mechta-Grigoriou
Fatima Mechta-Grigoriou is a French cancer biologist, Research Director at Inserm and director of the Stress and Cancer laboratory at Institut Curie in Paris, elected an EMBO Member in 2016.
Fatsia japonica (ヤツデ)
Fatsia japonica (ヤツデ, yatsude), Japanese aralia or glossy-leaved paper plant, an evergreen Araliaceae shrub from Korea and Japan with 9-lobed glossy leaves, October-November white flowers, black fruit, and the Hedera hybrid ×Fatshedera.
Fatty acid activation and acyl-CoA synthetases
Fatty acid activation and acyl-CoA synthetases are enzymes that attach fatty acids to CoA. Mammalian genomes encode a large family of these enzymes, sorted by chain length.
Fatty acid desaturase
Fatty acid desaturases (FAD, FADS1/2, SCD, FAD2) are enzymes that insert double bonds into fatty acyl chains using a di-iron active site, producing unsaturated and polyunsaturated fatty acids for membranes, health, and engineered seed oils.
Fatty acid elongation
Fatty acid elongation is the extension of fatty acyl-CoA chains by two carbons per cycle, carried out mainly in the endoplasmic reticulum to produce very long-chain fatty acids.
Fatty acid hydroxylase-associated neurodegeneration
Fatty acid hydroxylase-associated neurodegeneration (FAHN, SPG35) is a very rare autosomal recessive NBIA disorder caused by FA2H mutations, with childhood-onset dystonia, spastic paraplegia, ataxia, optic atrophy, and globus pallidus iron.
Fatty acid metabolism
Fatty acid metabolism is the set of biochemical pathways by which organisms break down fatty acids for energy (β-oxidation) and synthesize them for storage and membrane building.
Fatty acid synthase
Fatty acid synthase (FASN, EC 2.3.1.85), the homodimeric cytoplasmic enzyme of de novo lipogenesis that condenses acetyl-CoA and malonyl-CoA with NADPH to make palmitate; type I versus type II forms, regulation, and inhibitors.
Fatty acid synthesis
Fatty acid synthesis (lipogenesis): cytosolic de novo pathway building palmitate from acetyl-CoA via malonyl-CoA, acetyl-CoA carboxylase as rate-limiting enzyme, NADPH-dependent fatty acid synthase; distinct from beta-oxidation and the source of essential-fatty-acid biology.
Fatty acid synthesis PlsX protein
PlsX (phosphate acyltransferase) is the bacterial enzyme converting acyl-ACP to acyl-phosphate, first step of the PlsX/PlsY/PlsC pathway to phosphatidic acid; essential in Bacillus subtilis and the coupling point of fatty acid and phospholipid synthesis.
Fatty acid-binding protein
Fatty acid-binding proteins (FABPs) are small intracellular proteins that bind fatty acids, with ten mammalian members, FABP1 through FABP9 plus FABP12, each tied to a characteristic tissue.
Fatty acid-binding protein, intestinal
FABP2, also known as intestinal fatty acid-binding protein (I-FABP), is a human protein-coding gene on chromosome 4q26 whose protein carries long-chain fatty acids in small-intestinal enterocytes.
Fatty acids
Fatty acids: long-chain carboxylic acids serving as energy substrates, membrane components, and signaling precursors. Classes SFA, MUFA, PUFA; essential omega-3 and omega-6; beta-oxidation; dietary health effects.
Fatty acids: potassium salt tall oil fatty acid
Fatty acids, tall-oil, potassium salts (potassium tallate, CAS 61790-44-1) is a UVCB potassium soap of tall oil fatty acids from kraft pulping, used as surfactant, emulsifier, and cleaning agent; low hazard, FDA food-contact listed, EU pesticide not approved.
Fatty acyl-AMP ligase /fatty acyl-CoA ligase
Fatty acyl-AMP ligases (FAALs), homologs of fatty acyl-CoA ligases (FACLs), are ANL-family enzymes that activate fatty acids as acyl-AMP and transfer them to ACP rather than CoA, discovered in Mycobacterium tuberculosis.
Fatty acyl-CoA reductase 1 deficiency
Fatty acyl-CoA reductase 1 deficiency (FAR1 deficiency, PFCRD, RCDP type 4) is a rare autosomal recessive peroxisomal plasmalogen-biosynthesis disorder (FAR1, 11p15.3, OMIM 616154) causing severe intellectual disability, congenital cataracts, early-onset epilepsy, microcephaly, and spastic quadriparesis without rhizomelia.
Fatty liver disease
Fatty liver disease, now called MASLD (formerly NAFLD), is excess liver fat not caused by alcohol, ranging from simple steatosis to MASH with fibrosis; treated with weight loss, resmetirom, and semaglutide.
Fatty-acid-binding protein 1
Fatty-acid-binding protein 1 (FABP1, L-FABP), liver-type cytosolic lipid-binding protein of the FABP family; binds two fatty acids plus endocannabinoids, shuttles ligands to PPARα, and serves as a tubular-injury biomarker.
Fauna
Fauna is the animal life of a particular region or time, the counterpart of flora. Covers faunal scope layers, Linnaean naming, survey and genetic methods, and conservation status scales.
Fauna of Australia
Fauna of Australia: the continent's native animals, defined by Gondwanan isolation, marsupial dominance (over 70% of world species), monotremes, high endemism (83% of mammals), and a severe extinction and threatened-species record under the EPBC Act.
Fauna of India
Fauna of India: the animal life of India, documented by the Zoological Survey of India (est. 1 July 1916) through the Fauna of India publication series, the National Zoological Collection of over a million specimens, and 16 regional centres.
Fauna of Louisiana
The fauna of Louisiana, also known as its wildlife, is the animal life of the subtropical state, from black bears in bottomland forests to Gulf fisheries worth about $1 billion a year.
Fauna of the United States
Fauna of the United States: animal life of the US, also called American wildlife. 1,590 terrestrial vertebrate species modeled by USGS GAP; 40% of animals at extinction risk per NatureServe; governed by the Endangered Species Act and Migratory Bird Treaty Act.
Fausto Roila
Fausto Roila is an Italian medical oncologist known for research on preventing chemotherapy-induced nausea and vomiting and for leading the MASCC and ESMO antiemetic guidelines.
Favezelimab
Favezelimab (MK-4280), Merck's humanized anti-LAG-3 IgG4 antibody, was tested with pembrolizumab (MK-4280A) in colorectal cancer and Hodgkin lymphoma; development was discontinued in December 2024 after phase 3 KEYFORM-007 missed overall survival.
Favipiravir
Favipiravir (Avigan, T-705, Favilavir) is a broad-spectrum antiviral from Toyama Chemical/Fujifilm that inhibits viral RNA polymerase by lethal mutagenesis; approved in Japan in 2014 for pandemic influenza, trialed widely for COVID-19 and Ebola with limited evidence of benefit.
FAVOR trial
FAVOR trial (Fimasartan, Atenolol, and Valsartan On haemodynamic paRameters in ischaemic stroke), NCT02403349: 12-week Korean double-blind randomized trial, 105 patients, showing ARBs lowered central BP and cerebral pulsatility more than atenolol.
Favosites
Favosites, the honeycomb coral, is an extinct cerioid tabulate coral genus named by Lamarck in 1816, type species F. gothlandicus, with polygonal corallites linked by mural pores, Silurian-Devonian reef habitats, and calcite skeletons.
FAWD study
The FAWD study (Factors Associated With Dermatoporosis) was a Mexican cross-sectional study that found dermatoporosis in 29% of 315 patients over 60, linked to age, sun exposure, and anticoagulants.