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H.C. Stansel
Horace C. Stansel was a pediatric cardiac surgeon at Yale New Haven Hospital and Yale School of Medicine from the 1960s until his death in 1994.
H.J. Evans
H.J. Evans, also known as H. John Evans, was a Welsh human cytogeneticist who directed the MRC Human Genetics Unit in Edinburgh from 1969 to 1994, known for chromosome banding.
H.L. Kornberg
H.L. Kornberg, born Hans Leo Kornberg (1928–2019), was a British-American biochemist who discovered the glyoxylate cycle, coined the term "anaplerotic" reactions, and held biochemistry chairs at Leicester, Cambridge, and Boston University.
H.R. Mahler
Henry R. Mahler (died July 1983) was a biochemist and molecular biologist at Indiana University Bloomington, remembered as "Mr. Mitochondria" for his yeast mitochondrial genetics research.
H/ACA box snoRNAs
H/ACA box snoRNAs are small non-coding RNAs with a conserved two-hairpin structure that guide pseudouridylation of ribosomal RNA and snRNAs, working with the pseudouridine synthase dyskerin; humans have 190.
H/ACA ribonucleoprotein complex, subunit Gar1/Naf1
Gar1/Naf1 domain family of box H/ACA ribonucleoproteins: Gar1 is a mature RNP core subunit and Naf1 an assembly factor; both bind the pseudouridine synthase Cbf5/dyskerin at a shared, structurally homologous surface, with Naf1 replaced by Gar1 during maturation.
H/St
H/St (C3H/St) is a substrain of the C3H inbred laboratory mouse, used in Strong and Matsunaga's 1977 study of a transmissible entity causing regression of spontaneous mammary tumors.
H&E stain
H&E stain (hematoxylin and eosin), also called haematoxylin-eosin, is the routine histopathology stain: hematoxylin with a metal mordant colors nuclei blue-purple, eosin colors cytoplasm pink; derived from logwood, established 1875–1878.
H1 antagonist
H1 antagonist (H1-antihistamine): inverse agonist drug blocking histamine at the H1 receptor; first synthesized 1937 by Bovet; first-generation (1942 onward) sedating, second-generation (cetirizine, loratadine, fexofenadine) non-sedating first-line for rhinitis and urticaria.
H1-0
H1-0, also written H1F0, is the human gene encoding histone H1.0, a linker histone on chromosome 22 that accumulates as cells stop dividing and condenses chromatin.
H1-1
H1-1 (H1.1, formerly HIST1H1A, HGNC:4715) is a human intronless gene at 6p22.2 encoding the replication-dependent linker histone H1.1, a weak chromatin condenser with a distinct genomic binding profile among H1 subtypes.
H1-10
H1-10 (H1FX, H1X, histone H1x) is a human gene on chromosome 3q21.3 encoding histone H1.10, a replication-independent somatic linker histone of 213 amino acids that binds active chromatin, nucleoli, and mitotic chromosomes.
H1-2
H1-2 (formerly HIST1H1C, HGNC:4716) is the human gene encoding H1.2, a 213-amino-acid replication-dependent linker histone on chromosome 6 that reads H3K27me3, compacts chromatin, silences growth-suppressive genes, and mediates DNA damage-induced apoptosis.
H1-4
H1-4 (HIST1H1E) is the human gene encoding histone H1.4, a replication-dependent linker histone on chromosome 6 that compacts chromatin, carries distinctive PTMs (K26me, S27p, S35p, K34ac), and whose frameshift mutations cause Rahman syndrome.
H1-5
H1-5 is the human gene encoding histone H1.5, one of eleven mammalian linker histone variants, located in the major histone cluster on chromosome 6 and implicated in chromatin condensation, gene regulation, and centromere integrity during mitosis.
H19 (gene)
H19 is a human gene on chromosome 11 that produces a long noncoding RNA and is a classic example of genomic imprinting, with only the maternal copy typically active.
H2/G
H2/G (H-2G) is the former name of the mouse H2g MHC haplotype and the HTG inbred strain, developed by Gorer about 1937 as an H2 recombinant; distinct from NOD's H2g7.
H2AX
H2AX (H2AFX, H2A.X) is a replication-independent histone H2A variant, 2.5–25% of mammalian H2A, whose ATM/ATR/DNA-PK phosphorylation on Ser139 (γH2AX) marks DNA double-strand breaks and supports repair, biodosimetry, and non-canonical chromatin roles.
H3-4
H3-4 (H3.4, H3t, HIST3H3) is a human gene on chromosome 1q42.13 encoding histone H3.4, a mammalian, testis-enriched H3 variant essential for spermatogenesis, forming less stable nucleosomes than canonical H3.
H3B-6545
H3B-6545 is Eisai's oral selective estrogen receptor covalent antagonist (SERCA) that covalently binds C530 of ERalpha, inhibiting wild-type and mutant receptor in ER+/HER2- breast cancer; phase 1/2 testing showed 450 mg QD with ORR 20.2% and higher activity in ESR1 Y537S-mutant disease.
H3K27me3
H3K27me3 is the trimethylation of lysine 27 on histone H3, a Polycomb repressive complex 2 (PRC2/EZH2) mark of facultative heterochromatin that silences developmental genes, propagates via EED-mediated feedback, and is erased by UTX and JMJD3.
Haast's eagle
Haast's eagle (Hieraaetus moorei, formerly Harpagornis moorei; Māori pouākai) was New Zealand's extinct giant eagle, the largest known, weighing up to 15 kg, hunting moa, descended from the little eagle, extinct 500–600 years ago.
Haatem Reda
Haatem M. Reda is a neurologist at Massachusetts General Hospital in Boston and Assistant Professor of Neurology at Harvard Medical School, known for neuromuscular and autoimmune neurology.
Habanero
Habanero, a cultivar group of Capsicum chinense from the Amazon Basin, is a very hot chili at 100,000–350,000 SHU with fruity aroma, domesticated over 6,000 years, centered in Mexico's Yucatán.
Habenaria
Habenaria, also called bog orchids, a large genus of about 600 to over 800 terrestrial tuberous orchids, pantropical to southern Siberia, polyphyletic in current phylogenies and split into Asian-Australian and African-American-Asian clades.
Haberma tingkok
Haberma tingkok (汀角攀树蟹), Ting Kok Tree Climbing Crab, is a sesarmid micro-mangrove crab described in 2017 from Hong Kong, the only known arboreal Haberma species, climbing Kandelia obovata mangroves at 1.5–1.8 m and recorded only from Tolo Harbour.
Habia
Habia (ant-tanagers) is a genus of Neotropical Cardinalidae passerines established by Blyth in 1840, including the Red-crowned, Red-throated, Black-cheeked, Sooty, and Crested ant-tanagers; some classifications move four species to Driophlox.
Habit reversal training
Habit reversal training is a behavioral therapy that treats tics, nervous habits, and body-focused repetitive behaviors by training patients to detect the behavior early and perform an incompatible competing response.
Habitat
A habitat, also called a natural habitat, is the place and set of environmental conditions where a plant or animal normally lives, ranging from landscapes to microhabitats.
Habitat destruction
Habitat destruction, also known as habitat loss, is the loss or degradation of natural habitat to human uses such as agriculture and urbanization, the primary cause of declining biodiversity.