6 articles
C–H cyanation
C–H cyanation is a class of chemical reactions that replaces a hydrogen atom on a carbon–hydrogen bond with a cyano group, converting substrates directly into organic nitriles without prior functionalization.
Cyanohydrin
A cyanohydrin, also called a hydroxynitrile, is an organic compound bearing a hydroxyl and a nitrile group on the same carbon, formed by adding HCN to aldehydes or ketones.
Kolbe nitrile synthesis
The Kolbe nitrile synthesis is an organic reaction that prepares alkyl nitriles by reacting alkyl halides with metal cyanides, extending the carbon chain by one atom.
Nickel-catalyzed cyanation
Nickel-catalyzed cyanation is a family of organic reactions in which a nickel catalyst installs a cyano group onto organic molecules, first reported by the Cassar group in 1973.
Nitrile anion
A nitrile anion is a stabilized carbanion formed by deprotonating the carbon adjacent to a nitrile group, widely used in organic synthesis to form carbon–carbon bonds.
Nitrile reduction
Nitrile reduction is the chemical conversion of an organic nitrile into a primary amine or, with partial reduction, an aldehyde, and is a major route to amines.