6 articles
Ethosuximide
Ethosuximide, sold as Zarontin, is a succinimide anticonvulsant first synthesized in 1927 and introduced in 1958, used to treat absence seizures and ineffective against tonic-clonic seizures.
Hydantoin
Hydantoin (imidazolidine-2,4-dione) is a five-membered heterocyclic compound with formula C₃H₄N₂O₂, isolated by Baeyer in 1861 and valued as a drug scaffold, including the anticonvulsant phenytoin.
Imide
An imide is a functional group in which a single nitrogen atom is bonded to two carbonyl groups, known for examples such as succinimide and phthalimide, the brominating reagent N-bromosuccinimide, and polyimide polymers.
Maleimide
Maleimide (C4H3NO2) is a five-membered cyclic dicarboximide and strong Michael acceptor for thiols, widely used for protein bioconjugation, antibody–drug conjugates such as Adcetris, and thermosetting bismaleimide resins.
Naphthalimide
Naphthalimide is a bicyclic organic compound of formula C12H7NO2, a naphthalene ring system fused to an imide at the 1,8 positions, whose derivatives are widely used fluorescent dyes and probes.
Phthalimide
Phthalimide is an aromatic imide and white crystalline solid whose acidity makes it the nitrogen source of the Gabriel synthesis; its derivatives appear in drugs, dyes, and polymers.