519,064 articles
Thioflavin T
Thioflavin T is a benzothiazole cationic dye that fluoresces strongly when bound to amyloid fibrils, the most widely used probe for detecting protein aggregation in vitro.
Thioglycolic acid
Thioglycolic acid, also known as mercaptoacetic acid, is a sulfur-containing carboxylic acid that reduces keratin disulfide bonds, making it the active agent in permanent waves, hair straighteners, and depilatories.
Thioguanine
Thioguanine (6-thioguanine, also tioguanine) is a purine antimetabolite drug synthesized by Gertrude Elion and George Hitchings, used mainly in combination chemotherapy for acute myeloid leukemia and at low doses for inflammatory bowel disease.
Thioketone
A thioketone, also called a thione, is an organosulfur compound in which the oxygen atom of a ketone is replaced by divalent sulfur, formula R2C=S.
Thiokol
Thiokol, also known as Morton Thiokol or Thiokol Chemical Corporation, was an American company founded in 1929, first commercial producer of synthetic rubber in the United States and maker of the Space Shuttle boosters.
Thiol
Thiols, formerly known as mercaptans, are organosulfur compounds of structure RSH, the sulfur analogs of alcohols, with strong skunky odors and a role in natural gas odorization.
Thiol properties and synthesis
Thiols, also called mercaptans, are organosulfur compounds of the form R–S–H, the sulfur analogs of alcohols; they are more acidic than alcohols and oxidize first to disulfides.
Thiol protecting groups
Thiol protecting groups are chemical groups that mask cysteine's thiol during peptide synthesis; more than 60 exist, including trityl, Acm, and StBu, each removed by different reagents.
Thiol-ene reaction
The thiol-ene reaction is the radical-mediated addition of a thiol across a carbon-carbon double bond, typically giving an anti-Markovnikov thioether; it is classed as a click reaction and used in coatings, adhesives, and 3D printing.
Thiol-mediated hydrogen atom transfer cocatalysis
Thiol-mediated hydrogen atom transfer cocatalysis is a radical catalysis mode in which a thiol cocatalyst, acting through its thiyl radical, shuttles hydrogen atoms while a photoredox or metal catalyst generates radical intermediates.
Thiol–disulfide exchange
Thiol–disulfide exchange, also called thiol–disulfide interchange, is the reaction in which a thiolate anion attacks a disulfide's sulfur atom, breaking one S–S bond and forming a new one, transferring the linkage.
Thiol:disulfide interchange protein DsbC
DsbC (thiol:disulfide interchange protein, UniProt P0AEG6) is an E. coli periplasmic protein disulfide isomerase, EC 5.3.4.1, a 23.5-kDa-subunit homodimer kept reduced by DsbD that repairs incorrect disulfide bonds and aids recombinant protein folding.
Thiolactone
A thiolactone is a cyclic thioester, the sulfur analog of a lactone, found in synthetic building blocks like γ-thiobutyrolactone, in homocysteine thiolactone formed in all organisms, and in bacterial signaling peptides.
Thiolase
Thiolase (acetyl-CoA acetyltransferase; 3-ketoacyl-CoA thiolase) is a CoA-dependent enzyme family catalyzing thiolytic cleavage of 3-ketoacyl-CoA and reverse Claisen condensation, using two catalytic cysteines; types I (EC 2.3.1.16) and II (EC 2.3.1.9) drive beta-oxidation, ketogenesis, and sterol synthesis.
Thiolate-protected gold cluster
A thiolate-protected gold cluster is an atomically precise particle of gold, formula Aun(SR)m, whose gold core below about 2 nm is stabilized by thiolate ligands and behaves molecularly.
Thiolation of wobble uridine in tRNA
Thiolation of wobble uridine in tRNA is the enzymatic replacement of uridine 34's oxygen with sulfur, forming 2-thiouridine in tRNAs for glutamate, glutamine, and lysine.
Thiomersal
Thiomersal (thimerosal, merthiolate) is an ethylmercury-based preservative used in multi-dose vaccine vials since the 1930s; removed from US childhood vaccines in 2001 as a precaution, with no evidence it causes autism.
Thiometon
Thiometon (CAS 640-15-3), also sold as Ekatin, is a systemic organophosphorus insecticide and acaricide controlling aphids, mites, and sawflies on many crops; a cholinesterase-inhibiting contact and stomach poison formerly registered in over 50 countries.
Thionazin
Thionazin (Zinophos), C8H13N2O3PS, an obsolete organophosphate soil insecticide and nematicide; acetylcholinesterase inhibitor with rat oral LD50 12 mg/kg, not EU-approved, EPA waste code P040.
Thionin
Thionins (purothionins, hordothionins, viscotoxins) are plant-only antimicrobial peptides of about 5 kDa, basic and cysteine-rich, first isolated from wheat in 1942; they kill microbes by binding membrane phospholipids and lysing cells.
Thionitrous acid
Thionitrous acid (HSNO) is an unstable inorganic S-nitrosothiol, formed from hydrogen sulfide and S-nitrosoglutathione and proposed as a link between nitric oxide and hydrogen sulfide signaling.
Thionoester
A thionoester is a carboxylic acid derivative of formula R–C(=S)–O–R′, an ester whose carbonyl oxygen is replaced by sulfur, usually made with Lawesson's reagent or P₄S₁₀.
Thionyl chloride
Thionyl chloride (SOCl2), also called sulfinyl chloride, is a fuming inorganic liquid that converts alcohols and acids to chlorides and powers lithium thionyl chloride batteries.
Thiophanate
Thiophanate, chiefly thiophanate-methyl (Topsin M), is a systemic benzimidazole-class fungicide introduced in 1970 that converts to carbendazim; used on crops, turf, and ornamentals, with EU approval not renewed in 2020 but continued US registration.
Thiophanate methyl
Thiophanate methyl (thiophanate-methyl, Topsin M) is a systemic MBC (FRAC 1) fungicide introduced in 1970, acting on fungal β-tubulin, metabolized to carbendazim, and no longer approved in the EU since 19 October 2020.
Thiophene
Thiophene is an aromatic five-membered heterocyclic organic compound with formula C₄H₄S, the sulfur analog of furan and pyrrole, whose ring appears in pharmaceuticals, agrochemicals, and electronic materials.
Thiophenol
Thiophenol, also known as benzenethiol or phenyl mercaptan, is the simplest aromatic thiol, a foul-smelling, highly toxic liquid used mainly as an intermediate for pesticides, pharmaceuticals, and amber dyes.
Thiophosphate
Thiophosphate is a phosphate in which one or more oxygen atoms bound to phosphorus are replaced by sulfur, forming anions, insecticidal esters, and lithium battery electrolytes.
Thioredoxin
Thioredoxin (Trx) is a small, ubiquitous redox protein, about 12 kDa, that reduces disulfide bonds in proteins and, with thioredoxin reductase and NADPH, forms one of the cell's principal antioxidant systems.
Thioredoxin H-type-like
Thioredoxin H-type-like (InterPro IPR050620) is a protein family of h-type thioredoxins, cytosolic plant disulfide reductases with a WC[G/P]PC active site, reduced by NADPH-thioredoxin reductase and central to seed germination and redox signaling.