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Thioredoxin reductase
Thioredoxin reductase (TrxR, EC 1.8.1.9), also TXNRD, is a homodimeric NADPH-dependent flavoenzyme that reduces oxidized thioredoxin; mammalian forms are selenoproteins (TrxR1, TrxR2, TGR) and drug targets in cancer and parasitic disease.
Thioridazine
Thioridazine, formerly marketed as Mellaril, is a phenothiazine antipsychotic first synthesized in 1958 that was used for psychoses including schizophrenia until branded versions were withdrawn worldwide in 2005 over cardiac arrhythmia risk.
Thiosemicarbazide
Thiosemicarbazide, also called aminothiourea, is an organic compound with formula CH₅N₃S, used as a chemical intermediate, analytical reagent, and rodenticide, and is fatal if swallowed.
Thiosulfate
Thiosulfate is a divalent sulfur oxoanion with the formula S2O3(2-), a sulfate analog in which one oxygen is replaced by sulfur, most often encountered as sodium thiosulfate.
Thiosulfate dehydrogenase
Thiosulfate dehydrogenase (TsdA), EC 1.8.2.2, is a periplasmic diheme c-type cytochrome that reversibly condenses two thiosulfate molecules into tetrathionate, releasing two electrons; distinct from TQO and SoxAX.
Thiosulfate sulfurtransferase domain-containing protein
Thiosulfate sulfurtransferase domain-containing proteins carry the rhodanese fold; the prototype TST (EC 2.8.1.1, rhodanese) is a mitochondrial enzyme detoxifying cyanide to thiocyanate and regulating H2S and Fe–S sulfur metabolism.
Thiosulfate sulfurtransferase, bacterial
Bacterial thiosulfate sulfurtransferase (rhodanese, EC 2.8.1.1), e.g. E. coli GlpE and PspE, transfers sulfane sulfur from thiosulfate to cyanide or dithiols via a cysteine persulfide intermediate, supporting cyanide detoxification, sulfur trafficking, and thiosulfate assimilation.
Thiosultap sodium
Thiosultap sodium (monosultap; disodium salt bisultap/dimehypo) is a nereistoxin-analogue, IRAC Group 14 nAChR channel-blocker insecticide, a pro-insecticide converting to nereistoxin, used mainly on rice stem borers; first registered Japan 1993, not EU-approved.
Thiotepa
Thiotepa, also known as triethylenethiophosphoramide, is a synthetic alkylating agent used in cancer chemotherapy, patented in 1952 and most used today before stem cell transplantation.
Thiothixene
Thiothixene (tiotixene, brand Navane) is a first-generation thioxanthene antipsychotic approved in the US in 1967 for schizophrenia; D2 antagonist, 20-30 mg/day typical dose, brand discontinued with generics remaining.
Thiouracil
Thiouracil is a sulfur-containing uracil derivative that inhibits thyroid peroxidase and blocks thyroid hormone synthesis; the first thionamide antithyroid drug, it was abandoned for toxicity.
Thiourea
Thiourea, also called thiocarbamide, is an organosulfur compound with formula CH₄N₂S, the sulfur analog of urea, used as an industrial intermediate and gold leaching reagent.
Thiourea organocatalysis
Thiourea organocatalysis is a branch of organocatalysis in which metal-free thiourea derivatives activate substrates through dual hydrogen bonding; chiral thioureas like Takemoto's 2003 catalyst are prominent in asymmetric synthesis.
Thip Chang
Thip Chang, also called Pho Chao Thip Chang, was an eighteenth-century elephant handler from Lampang, Thailand, who liberated the city from Burmese control and founded the Thipchak dynasty.
Thiram
Thiram, also known as tetramethylthiuram disulfide or TMTD, is a dithiocarbamate fungicide introduced in 1931 and used for seed treatment, as an animal repellent, and as a rubber accelerator.
Third Amendment to the United States Constitution
The Third Amendment to the U.S. Constitution, or Amendment III, bars quartering soldiers in private homes without consent in peacetime. Rooted in the Quartering Acts, it has never been decided by the Supreme Court; Engblom v. Carey is its leading case.
Third Anglo-Afghan War
The Third Anglo-Afghan War (War of Independence), May-June 1919: Amanullah's Afghanistan invaded British India; the Treaty of Rawalpindi of 8 August 1919 recognized full Afghan independence.
Third Anglo-Burmese War
The Third Anglo-Burmese War (तीसरा आंग्ल-बर्मा युद्ध), fought in November 1885, was the final conflict between Britain and Burma's Konbaung kingdom, ending with King Thibaw's deposition and the annexation of Upper Burma in 1886.
Third Anglo-Maratha War
Third Anglo-Maratha War, also the Pindari War (1817–1818): final East India Company victory over the Maratha Confederacy. Baji Rao II's defeats at Kirkee, Koregaon, and Mahidpur ended the Peshwa's office; the Company took Gujarat, Maharashtra, Rajasthan, and Berar.
Third Anglo-Mysore War
The Third Anglo-Mysore War (1790–1792) began when Tipu Sultan attacked Travancore and ended with his defeat by Lord Cornwallis's East India Company forces, ceding half his kingdom.
Third Arc Bio
Third Arc Bio Inc. is a clinical-stage biotechnology company based in Spring House, Pennsylvania, founded in 2022, developing multifunctional antibodies for solid tumors and inflammatory and immunology diseases.
Third Battle of Changsha
The Third Battle of Changsha (第三次长沙会战) was a Second Sino-Japanese War battle in Hunan, China, where Chinese forces under Xue Yue repelled the Japanese in January 1942.
Third Battle of Kharkov
Third Battle of Kharkov, or Manstein's Donets Campaign, February-March 1943 German counteroffensive by Army Group South and the SS Panzer Corps that recaptured Kharkov from the Soviets after Stalingrad and set the stage for Kursk.
Third Battle of Nola
The Third Battle of Nola, fought in 214 BC during the Second Punic War, saw the Roman consul Marcellus repel Hannibal's assault on Nola, killing over 2,000 Carthaginians.
Third Battle of Panipat
The Third Battle of Panipat, also called the Durrani Empire–Maratha Confederacy War, was fought on 14 January 1761 near Delhi, where Ahmad Shah Durrani's coalition destroyed the Maratha army.
Third Battle of Seoul
The Third Battle of Seoul, also called the Chinese New Year's Offensive, was a Korean War battle in which Chinese forces recaptured Seoul on 4 January 1951.
Third branchial cleft anomaly
Third branchial cleft anomaly (third branchial fistula, pyriform sinus tract): rare congenital neck malformation, 2–8% of branchial anomalies, left-sided, presenting as recurrent neck abscess or suppurative thyroiditis.
Third Buddhist Council
The Third Buddhist Council (तृतीय बौद्ध संगीति) was an assembly of Buddhist monks held at Pataliputra under Emperor Ashoka around 250 BC, presided over by Moggaliputta Tissa.
Third cabinet of Andrej Babiš
Third cabinet of Andrej Babiš (Třetí vláda Andreje Babiše), Czech three-party coalition of ANO, SPD, and Motorists for Themselves, appointed 15 December 2025, sworn in by President Petr Pavel, won confidence 15 January 2026.
Third cabinet of Cyril Ramaphosa
Third cabinet of Cyril Ramaphosa, the Government of National Unity executive of South Africa's seventh administration, announced 30 June 2024 with 32 ministers and 43 deputy ministers from eleven GNU parties; reshuffled in December 2024, November 2025, and June 2026.