All articles starting with P
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Platelet degranulation
Platelet degranulation: calcium-regulated exocytosis of platelet alpha granules, dense granules, and lysosomes via SNARE-mediated membrane fusion, releasing ADP, ATP, serotonin, fibrinogen, vWF, and growth factors at vascular injury sites.
Platelet function testing
Platelet function testing, also called platelet function tests, is a group of laboratory assays measuring platelet aggregation and activation to diagnose bleeding disorders and monitor antiplatelet drug effects.
Platelet transfusion
A platelet transfusion infuses donated platelets to prevent or treat bleeding caused by thrombocytopenia or platelet dysfunction, with about 2.2 million doses given yearly in the United States.
Platelet-activating factor
Platelet-activating factor (PAF), also called platelet-activating factor receptor ligand, is an ether phospholipid mediator of anaphylaxis, platelet aggregation, and inflammation, discovered by Benveniste in 1972 and targeted by PAF-R antagonists.
Platelet-activating factor receptor
Platelet-activating factor receptor (PAFR, PTAFR), a seven-transmembrane GPCR and first cloned lipid autacoid receptor, binds PAF and PAF-like lipids on platelets and immune cells; many antagonists exist but clinical efficacy has been limited.
Platelet-derived growth factor receptor
Platelet-derived growth factor receptor (PDGFR), also PDGFRα and PDGFRβ, a class III receptor tyrosine kinase pair binding PDGF-AA, -BB, -AB, -CC, and -DD dimers; cloned in 1986, targeted by imatinib, sunitinib, and other approved kinase inhibitors in cancer and fibrosis.
Platelet-derived growth factor receptor alpha
Platelet-derived growth factor receptor alpha (PDGFRα), encoded by the PDGFRA gene, is a receptor tyrosine kinase that binds platelet-derived growth factors, controlling cell growth, division, and survival.
Platelet-rich plasma
Platelet-rich plasma (PRP), also called platelet-rich fibrin or platelet concentrate, is an autologous blood product with platelets concentrated above baseline, used in orthopedics, wound care, dermatology, and fertility, with mostly low-quality clinical evidence.
Plateletpheresis
Plateletpheresis (platelet apheresis) collects platelets from one donor with a cell separator while returning other components; yields up to five whole-blood doses, repeatable 24 times yearly, also used therapeutically for thrombocytosis.
Plateosaurus
Plateosaurus, "flat lizard", a basal sauropodomorph dinosaur from the Late Triassic of Europe, named by von Meyer in 1837; known from huge miring bonebeds at Frick, Trossingen, and Halberstadt, with three valid species including P. trossingensis.
Platero and I
Platero and I (Platero y yo) is a prose poem book by Spanish poet Juan Ramón Jiménez about a silver donkey in Moguer, first published in 1914.
Platero y Tú
Platero y Tú was a Spanish rock band formed in Bilbao in 1989, fronted by Fito Cabrales, releasing eight albums before breaking up in 2001.
PlateUp!
PlateUp! is a 2022 co-op restaurant-management roguelite by It's happening and Yogscast Games: four players cook, automate, and survive 15-day procedurally generated restaurant runs, distinguished from Overcooked by persistent franchising progression.
Platform (站台)
Platform (站台, Zhantai) is Jia Zhangke's 2000 drama, his second feature, following a Fenyang, Shanxi theatre troupe from Maoist propaganda in 1979 to Cantopop by 1990; premiered at Venice 2000, NETPAC award and Golden Lion nomination.
Platform 7
Platform 7 is a four-part British supernatural thriller on ITVX (7 December 2023), adapted by Paula Milne from Louise Doughty's novel Platform Seven, starring Jasmine Jobson as Lisa, a ghost investigating her own death at Peterborough station.
Platform as a service
Platform as a service (PaaS) is a cloud computing model where the provider manages hardware, operating systems, and tools, and customers supply only their applications and data.
Platform Controller Hub
The Platform Controller Hub (PCH), also known as Intel PCH, is Intel's single-chip I/O controller connecting the processor to USB, SATA, PCIe, audio, and networking functions.
Platform Designer
Platform Designer, formerly known as Qsys, is the Intel Quartus Prime tool for assembling FPGA system-on-chip designs from IP components with automatically generated interconnect logic.
Platform economy
The platform economy is the part of the economy organized around digital platforms that connect groups of users, such as riders and drivers or buyers and sellers.
Platform screen doors
Platform screen doors (PSDs) are powered barriers along a platform edge that open and close with train doors, installed chiefly to prevent falls and entries onto the track.
Platform shoe
Platform shoe: footwear with a very thick, high sole under the whole foot. Known historically as chopines in Venice, revived by Ferragamo in 1938, disco-era 1970s, Spice Girls 1990s, and Balenciaga 2017.
Platform supply vessel
A platform supply vessel (PSV) is a ship purpose-built to carry cargo, equipment, and supplies between onshore bases and offshore oil and gas platforms, with an open deck aft and bulk tanks below.
Platform trial
A platform trial is a clinical trial design testing multiple treatments against a shared control group, with treatments entering or leaving under a master protocol.
Platform-M
Platform-M (Платформа-М) is a Russian small tracked, remotely controlled unmanned ground vehicle developed by NITI Progress in Izhevsk, typically armed with a PKT machine gun and grenade launchers.
Platformer
Platformer: video game genre centered on jumping between platforms. Began with Donkey Kong (Nintendo, 1981); Super Mario Bros. defined 2D, Super Mario 64 (1996) the first 3D; includes metroidvanias and 2.5D games.
PlatformIO
PlatformIO is an open-source ecosystem for embedded software development, built around a command-line tool and a Visual Studio Code extension for building, uploading, and debugging microcontroller projects.
Platichthys flesus
Platichthys flesus, the European flounder, is a catadromous right-eyed flatfish of the family Pleuronectidae from the White Sea to the Mediterranean and Black Sea; commercial fish, IUCN Least Concern, up to 60 cm and 2.9 kg.
Platichthys stellatus
Platichthys stellatus, the starry flounder (강도다리), a left-eyed righteye flounder of the North Pacific and Arctic, from Korea and Japan to California, growing to 91 cm, estuarine and river-entering, minor commercial fishery, IUCN Least Concern.
PLATIDE-PCI trial
PLATIDE-PCI (NCT02748330) is a completed phase 4, single-center randomized trial at Peking Union Medical College Hospital comparing ticagrelor versus clopidogrel platelet inhibition (VerifyNow PRU) in about 40 type 2 diabetic patients after elective PCI.
Platine War
The Platine War (1851–1852), also called Guerra contra Oribe e Rosas, was the war in which Brazil, Entre Ríos, and Uruguay defeated Rosas of Buenos Aires and his Uruguayan ally Manuel Oribe.