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All articles starting with P

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Plecanatide

Plecanatide (Trulance) is a 16-amino-acid uroguanylin analog and guanylate cyclase-C agonist, FDA-approved in 2017 at 3 mg once daily for adult chronic idiopathic constipation and IBS-C, with diarrhea as the main adverse effect.

Pleckstrin

Pleckstrin (PLEK1), platelet and leukocyte C-kinase substrate, is the major PKC substrate of platelets with two PH domains; its N-terminal PH domain structure (1994) named the widespread PH domain fold.

Pleckstrin homology domain

Pleckstrin homology (PH) domain: a ~100–120-residue protein module first defined in 1993 in pleckstrin; 11th most common human domain. A minority bind phosphoinositides with high affinity; others mediate protein interactions and membrane targeting.

Plecoglossus altivelis

Plecoglossus altivelis, the ayu or ayu sweetfish (Korean 은어), an amphidromous osmeriform fish of the family Plecoglossidae native to Japan, Korea, Taiwan, and China; IUCN Data Deficient, decreasing; major Japanese fishery and aquaculture species.

Plecoptera

Plecoptera is an order of insects known as stoneflies, with over 4,000 species on every continent except Antarctica; its aquatic nymphs need cool, oxygen-rich streams and signal high water quality.

Plecotus

Plecotus (big-eared bats) is a Palearctic genus of long-eared vesper bats in tribe Plecotini, type species P. auritus. Molecular work revealed at least 19 cryptic species; North American relatives belong to Corynorhinus.

Plectin-related limb-girdle muscular dystrophy R17

LGMD R17 (formerly LGMD2Q, MIM #613723) is an autosomal recessive limb-girdle muscular dystrophy caused by PLEC variants, mainly the exon 1f c.1_9del deletion, causing proximal weakness without skin involvement.

Plectranthus

Plectranthus L'Hér., a mint-family (Lamiaceae) genus described in 1788, formerly held about 450 Old World tropical species; molecular phylogenetics split it in 2019, moving most species to Coleus and Equilabium, leaving 72 in Plectranthus sensu stricto.

Plectrophenax

Plectrophenax is a small genus of Arctic buntings in the family Calcariidae, containing the Holarctic Snow Bunting and McKay's Bunting, which breeds only on two Bering Sea islands.

Plectropomus leopardus

Plectropomus leopardus, the leopard coralgrouper or common coral trout, is a western Pacific coral reef grouper; a protogynous hermaphrodite reaching 120 cm, it anchors the Great Barrier Reef fishery and the Asian live reef fish trade.

Plectrum

Plectrum, also called guitar pick: a small thin piece of plastic, metal, bone, or similar material used to pluck or strum strings of guitars, mandolins, and lyres, from Greek plêktron; modern celluloid guitar picks date to D'Andrea in 1922.

Pledge of Allegiance

The Pledge of Allegiance, also called the loyalty pledge to the U.S. flag, is the oath codified at 4 U.S.C. § 4, written by Francis Bellamy in 1892, made official in 1942, with "under God" added in 1954; Barnette (1943) bars compelled recitation.

Pledges of Aqaba

The Pledges of Aqaba (بيعتا العقبة) were two agreements sworn at Aqaba near Mecca between Muhammad and delegations from Yathrib in 621 and 622 CE.

Pledis Entertainment (플레디스 엔터테인먼트)

Pledis Entertainment (플레디스 엔터테인먼트) is a South Korean K-pop label founded by Han Sung-soo, home of SEVENTEEN and TWS, acquired by Big Hit (HYBE) in 2020 as an independent HYBE label.

Plegadis falcinellus

Plegadis falcinellus, the glossy ibis (Morito Común, Ibis falcinelle), is a cosmopolitan Threskiornithidae wading bird with iridescent dark plumage and a down-curved bill, Least Concern globally and expanding in range across Europe and North America.

Plegmund

Plegmund, who died in 914, was the 19th Archbishop of Canterbury from 890, a Mercian hermit summoned by King Alfred the Great as a learned adviser.

Pleiades

The Pleiades, also known as Messier 45 or the Seven Sisters, is a bright open star cluster in Taurus, about 445 light-years away, containing over 1,000 stars.

Pleiades (Πλειάδες) (Greek mythology)

Pleiades (Πλειάδες), also Atlantides or Vergiliae, the seven mythological daughters of Atlas and Pleione born on Mount Cyllene: Maia, Electra, Taygete, Alcyone, Celaeno, Sterope, and Merope, chased by Orion and turned into doves and stars in Taurus.

Pleiades in folklore and literature

The Pleiades in folklore and literature covers the myths and seasonal calendars built around the Pleiades star cluster, from the Greek seven sisters to Māori Matariki.

Pleiades Moving Group

The Pleiades Moving Group, also called the Local Association, is an unbound stream of young stars, 20 to 150 million years old, sharing the Pleiades cluster's motion.

Pleiades, The

The Pleiades is a Quaternary volcanic complex in northern Victoria Land, Antarctica, with about 20 scoria cones and domes rising to 3,040 m at Mount Atlas.

Pleione

Pleione D.Don, a genus of small deciduous Himalayan orchids (Orchidaceae, Coelogyninae) with cormose pseudobulbs, about 26 species from Nepal to Taiwan, originating in the Hengduan Mountains.

Pleiotropy

Pleiotropy: one gene or mutation affecting multiple phenotypic traits. Coined by Ludwig Plate in 1910; examples include Marfan syndrome, PKU, and sickle cell anemia; antagonistic pleiotropy underlies Williams' 1957 aging theory.

Pleistocene

The Pleistocene, often called the Ice Age, is the geological epoch from 2.58 million to 11,700 years ago, spanning Earth's most recent repeated glaciations before the Holocene.

Pleistocene Park

Pleistocene Park (Плейстоценовый парк) is a rewilding experiment near Chersky, Yakutia, founded by Sergey Zimov in 1996 on 144 km2, testing whether reintroduced large herbivores can restore mammoth steppe and slow permafrost thaw.

Plemmyrium (promontory)

Plemmyrium (Plemmyrion, modern Plemmirio/Maddalena Peninsula) is the promontory closing Syracuse's Great Harbour. Nicias fortified it with three forts in 414 BC; Gylippus captured them in 413 BC, a turning point of the Sicilian Expedition.

Plena

Plena is a Puerto Rican song-and-dance genre built on hand frame drums, born in working-class barrios of Ponce around the turn of the 20th century.

Plena Libre

Plena Libre is a Puerto Rican plena group founded in San Juan in 1994 by bassist Gary Núñez, known for adding a full salsa-style horn band to traditional plena.

Plenipotentiary

Plenipotentiary: a diplomatic agent holding full powers to represent a state in treaty-making, under VCLT Articles 2(1)(c) and 7; also the historical rank envoy extraordinary and minister plenipotentiary, below ambassador.

Plenty

Plenty is a 1978 play by David Hare, first staged at the National Theatre in London, following a former SOE courier's disillusionment in postwar Britain.