All articles starting with P
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Protea Rupes
Protea Rupes is a 147 km lobate scarp on Mercury near 9°S, 203°E, named in 2022 for a South African survey vessel, a thrust-fault landform showing recent tectonic grabens.
Proteaceae
Proteaceae, the protea family, a southern-hemisphere family of flowering plants in Proteales with about 80 genera and 1,750 species, centres of diversity in Australia and southern Africa, four-part flowers, and proteoid roots.
Proteales
Proteales, an order of basal eudicot flowering plants (APG IV), containing Nelumbonaceae, Platanaceae, Proteaceae, and Sabiaceae; includes proteas, sycamores, and the sacred lotus.
Protean eGov Technologies
Protean eGov Technologies, formerly NSDL e-Governance Infrastructure, is an Indian IT services company that processes PAN card applications and runs the National Pension System's recordkeeping.
proteanTecs
proteanTecs is an Israeli semiconductor analytics company founded in 2017 in Haifa by former Mellanox executives, embedding on-chip monitoring Agents in chip designs and raising $51 million in 2025.
Protease
Protease (peptidase, proteinase): enzyme hydrolyzing peptide bonds, EC 3.4. Classified into serine, threonine, cysteine, aspartic, glutamic, and metallo catalytic types; over 600 protease genes in humans; used in detergents, food, and drug discovery.
Protease A inhibitor IA3
Protease A inhibitor IA3 (IA₃, PAI3, saccharopepsin inhibitor) is a 68-residue, 8 kDa unstructured yeast protein that folds into an alpha-helix upon binding, potently and specifically inhibiting Saccharomyces cerevisiae proteinase A (Ki below 0.1 nM).
Protease inhibitor
Protease inhibitors block proteases, the enzymes that cleave peptide bonds; they span natural plant and microbial inhibitors, ACE inhibitors such as captopril (1981), and antivirals for HIV, hepatitis C, and COVID-19 (nirmatrelvir).
Protease-activated receptor
Protease-activated receptors (PARs), also called proteinase-activated receptors, are a family of four G protein-coupled receptors activated by proteolytic cleavage, with roles in hemostasis, inflammation, and pain.
Protease-activated receptor 2
Protease-activated receptor 2 (PAR2, F2RL1) is a GPCR activated by proteolytic cleavage exposing a tethered ligand (SLIGKV); the only thrombin-insensitive PAR, activated by trypsin and tryptase, linked to inflammation, pain, and cancer drug development.
Proteasome
Proteasome: the ubiquitin-tagged protein degrading 26S complex (20S core plus 19S regulator), a threonine protease central to proteostasis; includes the IFN-γ-induced immunoproteasome (β1i, β2i, β5i) and drug targets bortezomib, carfilzomib, ixazomib.
Proteasome (prosome, macropain) subunit, alpha 1
PSMA1 (proteasome subunit alpha type-1, alpha-6/C2, macropain C2) encodes a 263-aa structural subunit of the 20S proteasome core on human chromosome 11p15.1; distinct from prostate PSMA/FOLH1, it is implicated in gastric and lung cancers and nephrotic syndrome autoantibodies.
Proteasome assembly
Proteasome assembly is the ordered, chaperone-assisted process by which cells build the 26S proteasome, whose 20S core contains 28 subunits and degrades most regulated and damaged proteins.
Proteasome assembly chaperone 1
Proteasome assembly chaperone 1 (PAC1), encoded by the human PSMG1 gene, is a protein that assists assembly of the 20S proteasome core particle as part of the PAC1–PAC2 chaperone pair.
Proteasome assembly chaperone 2
PSMG2 (PAC2, HCCA3) is the human gene for proteasome assembly chaperone 2, which with PAC1/PSMG1 scaffolds alpha-ring assembly of the 20S proteasome and prevents alpha-ring dimerization; loss-of-function mutations cause PRAAS4/CANDLE autoinflammatory disease.
Proteasome assembly chaperone 3
Proteasome assembly chaperone 3 (PAC-3, hPAC3; gene PSMG3, C7orf48) is a human 122-aa, 13.1 kDa chaperone that, with PAC4, guides α-ring formation in 20S proteasome assembly and is linked to poor breast cancer prognosis.
Proteasome chaperone 1, fungi
Proteasome chaperone 1 in fungi, Poc1/Pba1/Irc25, is the yeast alpha-ring assembly chaperone of the 20S proteasome, pairing with Pba2/Poc2 as the ortholog of mammalian PAC1-PSMG1.
Proteasome subunits and assembly
Proteasome subunits and assembly describes the roughly 33 proteins of the 26S proteasome, whose 20S core and 19S regulatory particles assemble with chaperone help in eukaryotic cells.
Proteasome-associated autoinflammatory syndrome
Proteasome-associated autoinflammatory syndrome (PRAAS), also called CANDLE or Nakajo-Nishimura syndrome, is a rare autosomal recessive disorder causing rash, recurrent fever, joint contractures, and lipodystrophy beginning in infancy.
Protect (rapper)
Protect (Ricky Shanklin, born 2003, also Lil Tec/seeingfacess) is a Buffalo, New York rapper in the rage and cloud trap underground, signed to Ball Hogs/Atlantic through streamer BruceDropEmOff, known for "Ball Hog Summer" and albums All On Me, Ball Hog For Life, 500 Days of Summer, Slimedude2003.
Protect the Dolls
Protect the Dolls: slogan supporting trans women, from 1980s ballroom slang "dolls," popularized by Conner Ives' 2025 London Fashion Week T-shirt worn by Pedro Pascal, raising funds for Trans Lifeline.
ProtecT trial (NCT02044172)
The ProtecT trial was a UK randomized trial of active monitoring, prostatectomy, and radiotherapy for PSA-detected localized prostate cancer; all three arms had similar mortality.
Protected area
A protected area is a clearly defined space managed by law or other means for the long-term conservation of nature, under the IUCN definition adopted in 2008.
Protected areas of Polynesia and Micronesia
The protected areas of Polynesia and Micronesia are the Pacific islands' national parks, reserves, and marine sanctuaries, covering 6% of the region's land and 19.9% of its waters.
Protected health information
Protected health information (PHI) is individually identifiable health information held by HIPAA covered entities and business associates, protected by the Privacy and Security Rules, with de-identification, minimum necessary, and FTC gap coverage.
Protected landscape
Protected landscape (IUCN category V, protected landscape/seascape): a lived-in protected area where people–nature interaction over time created significant ecological, cultural, and scenic value, managed with local communities; over half of Europe's protected coverage.
Protected marine zone
Protected marine zone, or marine protected area (MPA), a legally designated ocean area managed for biodiversity conservation, from no-take reserves to multiple-use zones; over 10% of the ocean is now protected, with effectiveness depending on enforcement and protection level.
Protected species
A protected species is a species given legal protection from extinction by bans on killing, capture, trade, and habitat harm under laws such as the US Endangered Species Act, CITES, and the EU Habitats Directive.
Protected structure
A protected structure is an Irish building of special interest listed in a local authority's record of protected structures, protected under the Planning and Development Act 2000.
Protected Tactical SATCOM (PTES)
Protected Tactical SATCOM (PTES), or Protected Tactical Enterprise Service, is a United States Space Force ground system giving tactical warfighters jam-resistant satellite communications in contested environments.