RNA and gene regulation

MIR142

MIR142 is a human non-coding RNA gene at 17q22 that encodes microRNA miR-142, key to blood cell development and the most frequently mutated microRNA gene in cancer.

MIR143 (microRNA 143) encodes miR-143, a tumor-suppressive microRNA at human 5q32 clustered with miR-145; it regulates KRAS/ERK5 signaling, smooth muscle differentiation, insulin-AKT metabolism, and granulosa cell steroidogenesis.

MIR144

MIR144 (hsa-mir-144, microRNA 144), 17q11.2, encodes miR-144 of the GATA-1-regulated miR-144/451 cluster essential for erythropoiesis; knockout causes anemia; also a disease biomarker.

MIR145

MIR145, also written miR-145, is a human gene on chromosome 5 that makes microRNA-145, a short RNA acting as a tumor suppressor and vascular smooth muscle regulator.

MIR148A

MIR148A (miR-148a, hsa-mir-148a) is a human microRNA gene on chromosome 7p15.2 encoding a tumor-suppressive, inflammation-regulating microRNA of the miR-148/-152 family, dysregulated in many cancers.

MIR150

MIR150 (microRNA 150, miR-150) is a human microRNA gene at 19q13.33 encoding miR-150-5p, a RISC-loaded guide RNA regulating B and T cell development and studied as a diagnostic biomarker in cancer.

MIR155

MIR155 (microRNA 155, also MIRN155, mir-155) is a human non-coding RNA gene at 21q21.3 inside the MIR155HG/BIC host gene, encoding the oncomiR miR-155-5p, a key regulator of immunity, inflammation, cancer, and cardiovascular disease.

MIR15A

MIR15A (hsa-mir-15a) is a human microRNA gene at 13q14.2, cotranscribed with MIR16-1; deleted or downregulated in about two-thirds of CLL cases, it represses BCL2, MCL1, Cyclin D1, ROR1, and TP53 as a tumor suppressor.

MIR17

MIR17 (microRNA 17, hsa-mir-17) is a human non-coding RNA gene at 13q31.3, one of six miRNAs of the miR-17~92 cluster (oncomiR-1) in MIR17HG, an oncogenic microRNA regulating target mRNAs via RISC.

MIR17HG

MIR17HG (C13orf25, MIRHG1), the miR-17-92a-1 cluster host gene at 13q31.3, is an oncogenic human lncRNA hosting six microRNAs, amplified in lymphomas, deleted in Feingold syndrome 2, and targeted by antisense therapy.

MIR195

MIR195 (microRNA 195, miR-195) is a human non-coding RNA gene at 17p13.1 encoding a miR-15/107 family microRNA, studied as a circulating cancer biomarker and generally tumor-suppressive regulator.

MIR200C

MIR200C (microRNA 200c, miR-200c) is a human non-coding RNA gene on chromosome 12, member of the five-member miR-200 family, that represses EMT by targeting ZEB1/ZEB2 and acts as a metastasis suppressor and cancer biomarker.

MIR204

MIR204 (miR-204, hsa-mir-204) is a human microRNA gene at 9q21.12, intragenic within TRPM3, highly expressed in eye tissues, a tumor suppressor, and linked to retinal dystrophy-iris coloboma-congenital cataract syndrome.

MIR206

MIR206 (microRNA 206, hsa-mir-206) is a human non-coding RNA gene at 6p12.2 encoding a skeletal-muscle-specific microRNA of the miR-1/206 family, involved in myogenesis and studied as a biomarker in muscular dystrophy, ALS, SMA, and Alzheimer's disease.

MIR21

MIR21 (miR-21, hsa-mir-21), human microRNA gene at 17q23.1 producing a ~22-nt non-coding RNA; an oncomiR up-regulated in nearly all cancers, heart failure, and fibrosis, but a non-specific biomarker claimed by at least 29 diseases.

MIR210

MIR210 (microRNA 210, miR-210), the master hypoxamir on chromosome 11p15.5, is HIF-1α-induced under hypoxia, targets ISCU and EFNA3, is upregulated in most cancers, and serves as a candidate non-invasive liquid-biopsy biomarker.

MIR214

MIR214, or microRNA 214, is a human gene on chromosome 1q24.3 encoding microRNA-214, a non-coding RNA that represses gene expression and acts in cancer, heart, and kidney biology.

MIR22

MIR22 (microRNA 22, hsa-miR-22-3p, MIRN22) is a human microRNA gene at 17p13.3 hosted by MIR22HG; it targets PTEN and TET2, acts context-dependently in cancer, metabolism, and heart disease.

MIR221

MIR221 (microRNA 221, hsa-mir-221) is a human Xp11.3 non-coding RNA gene co-transcribed with miR-222; an oncomiR targeting p27, p57, and PTEN, studied as a cancer biomarker and target of the LNA-i-miR-221 inhibitor.

MIR223

MIR223 (microRNA 223, miR-223) is a human Xq12 non-coding RNA gene encoding a microRNA that regulates myeloid differentiation and innate immunity, acts as oncogene or tumor suppressor by tissue context, and serves as a circulating cancer biomarker.

MIR27A

MIR27A (microRNA 27a, hsa-mir-27a) is a human non-coding RNA gene at 19p13.12 producing the 22-nt miR-27a, which represses target mRNAs via RISC and acts as oncogene or tumor suppressor in cancer.

MIR29A

MIR29A (microRNA 29a, hsa-mir-29a, HGNC:31616) is a human non-coding RNA gene on chromosome 7q32.3 encoding miR-29a, a tumor-suppressive, antifibrotic microRNA clustered with miR-29b-1 and studied as a biomarker in cancer, fibrosis, and HIV-1.

MIR30A

MIR30A (microRNA 30a, HGNC:31624) is a human ncRNA gene at 6q13 producing miR-30a-5p and -3p strands; a miR-30 family tumor suppressor studied in renal cell carcinoma and kidney disease biomarkers.

MIR34A

MIR34A (microRNA 34a, miR-34a) is a human non-coding RNA gene on chromosome 1 encoding a p53-regulated tumor-suppressive microRNA of the miR-34 family; its liposomal mimic MRX34 was the first miRNA cancer therapy tested in patients.

MIR375

MIR375 (miR-375, hsa-mir-375) is a human microRNA gene at 2q35, first identified in pancreatic islets as a regulator of insulin secretion and beta-cell mass, and studied as a circulating diagnostic biomarker in prostate and other cancers.

MIR941-1

MIR941-1 (microRNA 941-1, HGNC:33684) is a human ncRNA gene at 20q13.33 producing miR-941, a human-specific microRNA that arose de novo from tandem repeats one to six million years ago and targets hedgehog and insulin signaling genes.

miRBase

miRBase is a public reference database of published microRNA sequences and official names, begun in 2002 as the MicroRNA Registry and now the field's de facto nomenclature authority.

Sep 29, 2026

miRNA microarray analysis

miRNA microarray analysis is a hybridization-based method that measures microRNA abundance in cells or tissues using fluorescently labeled miRNAs and thousands of immobilized complementary probes.

Sep 29, 2026

miRNA target prediction

miRNA target prediction is the set of computational methods that predict which messenger RNAs are regulated by microRNAs, mostly by searching for seed-region pairing and scoring candidate sites.