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Public health and healthcare

1,953 articles

TiLi-BONE study

TiLi-BONE (NCT07094568), Tirzepatide vs Liraglutide in Bone, a prospective observational cohort study by the National and Kapodistrian University of Athens comparing bone turnover markers (CTX, P1NP) and body composition in adults with BMI ≥40 kg/m² over 6 months.

Time series design (epidemiology)

A time series design in epidemiology is a quasi-experimental design measuring an outcome repeatedly over time to detect changes after an intervention, compared against the expected pre-existing trend.

Time trade-off

The time trade-off is a health economics survey method that values a health state by how much life expectancy people would give up for full health.

Time-location sampling

Time-location sampling, also called time-space sampling or venue-based sampling, is a probability survey method that recruits hard-to-reach populations at venues where they concentrate, developed in the late 1980s for HIV surveillance.

Timeline of the COVID-19 pandemic

Timeline of the COVID-19 pandemic: from the 31 December 2019 Wuhan pneumonia alert, WHO's 30 January 2020 PHEIC and 11 March 2020 pandemic declaration, through vaccines, Alpha, Delta, and Omicron variants, to the end of the emergency on 5 May 2023.

Timeline of the COVID-19 pandemic in the United Kingdom (January–June 2020)

Timeline of COVID-19 in the UK, January–June 2020: first cases late January, lockdown 23 March, first-wave peak in April, easing from 13 May, dexamethasone 16 June, and inquiry findings on lockdown delay.

Timeline of the opioid epidemic

Timeline of the opioid epidemic: US opioid overdose crisis from the 1980 Porter-Jick letter and 1995 OxyContin approval through three CDC waves (prescription opioids, heroin 2010, fentanyl 2013), 806,000 deaths 1999-2023, the 2022 peak, and the 2023-2025 decline.

Timothy G. Evans

Timothy Grant Evans is a Canadian physician and global-health leader who co-founded Gavi, led the WHO's Commission on Social Determinants of Health, and joined Concordia University in 2025.

Timothy R.B. Johnson

Timothy R.B. Johnson (1949–2025) was an American obstetrician at the University of Michigan who chaired its obstetrics department and built a physician training partnership with Ghana.

Timothy Ray Brown

Timothy Ray Brown, the "Berlin Patient," was the first person cured of HIV, via two 2007–2008 CCR5-delta32 stem cell transplants in Berlin for leukemia; he died September 29, 2020 of leukemia recurrence.

TiniPEA trial

TiniPEA (NCT06718452) is a randomized, quadruple-blind University of Campania Luigi Vanvitelli trial testing umPEALUT, co-ultramicronized palmitoylethanolamide plus luteolin, with or without rutin and 5-HTP, against placebo in 100 adults with tinnitus; not yet recruiting.

TME trial (NCT01872702)

TME trial (NCT01872702), or Targeted Chemo-elimination of Malaria, was a University of Oxford cluster-randomised trial (2013-2017) testing dihydroartemisinin-piperaquine mass drug administration in 16 Greater Mekong villages; falciparum prevalence fell 92% by month 3.

TOB-STOP-COP trial

TOB-STOP-COP (TOBacco STOP in COPd trial), NCT04088942, a Danish randomized multicenter trial testing high- versus low-intensity smoking cessation in 600 smokers with COPD; registry status withdrawn, no results posted.

Tobacco Control (concept)

Tobacco control: policies reducing tobacco use and smoke exposure, anchored in the WHO FCTC, the first global public health treaty (2003, in force 2005, 183 Parties), implemented through MPOWER measures.

Tobacco smoking

Tobacco smoking, mainly cigarette smoking, is the most common form of tobacco use: 1.2 billion users in 2024, prevalence down from 33.1% to 19.5% since 2000, over 7 million deaths yearly, regulated by the WHO FCTC and MPOWER.

Toilet Facilities

Toilet facilities are places and hardware for safe collection of human excreta, from household toilets to school and health-facility latrines; WHO/UNICEF track coverage, with 57% of people using safely managed sanitation in 2022.

Tolerability study

A tolerability study is a clinical study assessing how well participants can tolerate a drug or treatment, monitoring adverse effects, discontinuations, and patients' own experience of side effects.

Tongji Hospital

Tongji Hospital (华中科技大学同济医学院附属同济医院), Wuhan, founded 1900 in Shanghai by Erich Paulun, moved 1955; HUST teaching hospital with 5,613 beds, 43 national key specialties, fourth in CAMS STEM 2023; distinct from Shanghai's Tongji University hospital.

Tongren Hospital

Tongren Hospital (上海市同仁医院, St. Luke's Hospital), founded 1866 in Shanghai, is a Class A tertiary general hospital affiliated with Shanghai Jiao Tong University School of Medicine, serving 1.5 million people in Changning and the Hongqiao area.

TopIC-2 trial

TOPIC-2 (NCT02669459) was a Dutch randomized non-inferiority trial comparing intravaginal 5% imiquimod cream with LLETZ surgery for residual or recurrent cervical intraepithelial neoplasia; stopped early for futility after imiquimod succeeded in only 33% versus 100% for LLETZ.

Tracey Yap

Tracey Yap is an American nurse scientist and professor at the Duke University School of Nursing known for cueing interventions that prevent pressure injuries in long-term care.

Trans-Allegheny Lunatic Asylum

Trans-Allegheny Lunatic Asylum, also Weston State Hospital and West Virginia Hospital for the Insane: Kirkbride Plan psychiatric hospital in Weston, West Virginia, operated 1864-1994, built 1858-1881, now a privately owned tour site.

Transgender health care misinformation

Transgender health care misinformation: false claims about gender-affirming care, also called disinformation when intentional. Five documented themes, ROGD theory, regret-rate myths, and role in US care bans.

Transition to Adult Care

Transition to adult care (health care transition, HCT): the planned move of adolescents, especially those with chronic conditions, from child-centered pediatric services to adult-oriented care, using frameworks such as Got Transition's Six Core Elements and NICE guidance, with planning from about age 12 and transfer around 18 to 21.

Transitional Care

Transitional care, also called care transitions or home transition, is health care during a patient's move between care settings, chiefly hospital to home; evidence shows low- and medium-complexity interventions reduce readmissions and ED visits.

Transkidney trial

Transkidney (NCT02960802), a Turku University Hospital clinical trial, kidney transplantation and renal and myocardial perfusion; uses PET to measure coronary and renal flow reserve after transplant; active, not recruiting, no results posted.

TraQ trial

TraQ trial (NCT05085808), a withdrawn phase 4 USC pilot randomized trial comparing trazodone, quetiapine, and placebo for ICU delirium in surgical ICU patients at Keck Hospital; planned 30 patients, primary outcome delirium duration by CAM-ICU.

Trauma center

Trauma center: hospital specialized in definitive care of severely injured patients, classified ACS Levels I-V, designated by states and verified by the ACS; first U.S. centers opened 1966, Shock Trauma Center 1969.

Treatment as prevention

Treatment as prevention (TasP) is an HIV prevention strategy in which antiretroviral therapy suppresses the viral load of people with HIV, preventing sexual transmission to partners.

Treatment Delay

Treatment delay is a longer than expected or desired time between the onset of symptoms and the start of therapy, a Medical Subject Heading descriptor introduced in 2024.