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Human health and medicine

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Darunagaradi kvatha curna

Darunagaradi kvatha curna (Dārunāgarādi kvātha cūrṇa), an 18-ingredient Ayurvedic decoction powder from the Sahasrayoga, AFI Part-I 4:12, dose 48 g, used for fever (jvara) and ascites.

Darusentan

Darusentan (LU 135252, ABT-627) is an investigational selective endothelin ETA receptor antagonist for resistant hypertension; effective in phase 2 and DORADO trials but discontinued over fluid retention and a failed DORADO-AC endpoint, never approved.

Darvadstrocel

Darvadstrocel (Cx601, Alofisel) is an allogeneic adipose-derived mesenchymal stem cell therapy for complex perianal fistulas in Crohn's disease; EU-approved in 2018, withdrawn 13 December 2024 after ADMIRE-CD II failed.

Darvyadi kvatha curna

Darvyadi kvatha curna (Dārvyādi kvātha cūrṇa), also Darvyadi Kwatha, is an Ayurvedic Formulary of India coarse-powder decoction (AFI000586) of eight herbs including Berberis aristata, officially indicated for pradara (leukorrhea), with rat toxicology and prediabetes trials.

Das Gesundheitswesen

Das Gesundheitswesen is a monthly German-language Thieme journal (ISSN 0941-3790 print, 1439-4421 online) on public health and health services research, official organ of BVÖGD and six other societies, MEDLINE-indexed since 1992.

Das-181

DAS181 (Fludase, oplunofusp) is an inhaled recombinant sialidase fusion protein from Ansun BioPharma that cleaves host sialic acid receptors to block influenza and parainfluenza entry; in phase 3 development for parainfluenza in immunocompromised patients.

Dasabuvir

Dasabuvir (ABT-333, Exviera) is a non-nucleoside HCV NS5B polymerase inhibitor used with ombitasvir/paritaprevir/ritonavir (Viekira Pak) for genotype 1 hepatitis C; EU authorization withdrawn September 2024.

Dasamiularista

Dasamiularista (Dasamularista, Dashamularishta, Daśamūlāriṣṭa) is a fermented Ayurvedic arista tonic built on ten roots (daśamūla), with 5-10% self-generated alcohol, used for digestion, weakness, and postnatal recovery.

Dasamula ghrta

Dasamula ghrta (Daśamūla ghṛta), also called Dashamoola Ghrita, is a classical Ayurvedic medicated ghee made with ten roots, listed in the Ayurvedic Formulary of India at 12 g daily and used for Vata disorders such as arthritis and low back pain.

Dasamula haritaki (dasamulaharitaki)

Dasamula haritaki (Daśamūla harītakī), also called Dashamoola Haritaki lehyam, is a classical Ayurvedic semisolid avaleha of haritaki fruit cooked in ten-root dashamoola decoction with jaggery and honey; AFI dose 6-12 g for edema, splenic disease, and gulma.

Dasamula katutraya kvatha cirna

Daśamūla Kaṭutraya Kvātha Cūrṇa (Dashamoola Katutraya Kashayam) is an Ayurvedic Formulary of India Part I coarse-powder decoction of ten daśamūla roots, trikatu, and vasa, dosed at 48 g with honey for dyspnea, cough, flank, back, and vata disorders.

Dasamula kvatha

Dasamula kvatha (दशमूलक्वाथ) is a classical Ayurvedic decoction prepared from the roots of ten plants, used traditionally for pain, inflammation, fever, and postpartum disorders, and listed in the Ayurvedic Formulary of India as Dashamula Kvatha Churna.

Dasamula kvatha curna

Daśamūla Kvātha Cūrṇa (Dashamoola kwath churna) is the standardized Ayurvedic ten-root powder of AFI Part-I 4:10, five stem barks plus five whole plants in equal parts, decocted as Dashamoola kwatha for fever, pain, swelling, and Vata disorders.

Dasamula pancakoladi kvatha curna

Dasamula pancakoladi kvatha curna (Daśamūlapaṇcakolādi kvātha cūrṇa), an Ayurvedic coarse-powder decoction formula (API Part I 4:11, AFI000397), combining the ten Dashamula roots with Panchakola pungent drugs; dose 48 g; recorded uses include back pain and ascites.

Dasamula Taila

Dasamula Taila is an Ayurvedic medicated oil made by cooking the ten-root Dashamoola group into sesame oil, used in massage, enemas, and nasal or ear drops.

Dasamulasatpalaka ghrta

Daśamūlaṣaṭpalaka Ghṛta (Dashamulasatpalaka ghrta) is an official Ayurvedic medicated ghee made from the ten Daśamūla roots, six pungent drugs, milk, and cow's ghee, dosed at 12 g daily for appetite loss, anaemia, cough, indigestion, fever, and spleen disease.

Dasana Samskara Curna

Dasanamskara Curna (Daśana saṃskāra cūrṇa, Dashan Sanskar Churna) is an Ayurvedic tooth powder from Bhaishajyaratnavali, listed in the Ayurvedic Formulary of India (AFI000486), with khatika (calcium carbonate) plus ten herbal ingredients, used for dantadhavana and gum disease.

Dasanga Lepa

Dasanga Lepa (Dashanga Lepa), a classical Ayurvedic topical paste of ten herbs (Shirisha, Yashtimadhu, Tagara, Haridra, Kushtha, and others), used for inflammation, skin disease, and wounds; rare skin-rash ADR reported.

Dasatinib

Dasatinib (Sprycel, BMS-354825) is an oral dual Abl/Src tyrosine kinase inhibitor approved in 2006 for Ph+ CML and Ph+ ALL; 100 mg once daily first-line, active against most imatinib-resistant mutations except T315I.

DASH diet

DASH diet (Dietary Approaches to Stop Hypertension): NHLBI-developed eating plan rich in fruits, vegetables, whole grains, and low-fat dairy, sodium 2,300 or 1,500 mg/day, lowering blood pressure 5.5/3.0 mm Hg in the original 1997 trial.

Dasotraline

Dasotraline (SEP-225289) is an investigational dopamine and norepinephrine reuptake inhibitor developed by Sunovion for ADHD and binge-eating disorder; trials showed efficacy, but its NDAs were withdrawn in 2020 and it was never marketed.

Datopotamab deruxtecan

Datopotamab deruxtecan (Dato-DXd, DS-1062a, Datroway) is a TROP2-directed antibody-drug conjugate with a DXd topoisomerase I inhibitor payload, approved in the US for EGFR-mutated NSCLC, TNBC, and HR-positive HER2-negative breast cancer, and in the EU for breast cancer.

Daudi

Daudi (DAUDI, CVCL_0008) is a human Burkitt lymphoma B-lymphoblast cell line established in 1967 by the Kleins from a 16-year-old male; EBV-positive, MYC-IGH fusion, B2M-deficient, HLA class I-negative, standard for interferon assays.

Dave Asprey

Dave Asprey (born 1973), American entrepreneur, founder of Bulletproof and Bulletproof Coffee (butter and MCT oil in coffee), self-described father of biohacking; his diet and health claims face repeated scientific and fact-checking criticism.

David Agus

David Agus is an American medical oncologist and USC professor who is founding CEO of the Ellison Medical Institute and wrote the New York Times bestseller The End of Illness.

David C. Auth

David C. Auth is an American bioengineer and medical-device inventor known for the Rotablator coronary atherectomy device, who holds about 100 patents and joined the National Academy of Engineering in 2009.

David C. Sabiston Jr.

David C. Sabiston Jr., also known as David Coston Sabiston Jr., was an American cardiac surgeon who performed the first recorded coronary artery bypass in 1962 and led Duke's surgery department for 30 years.

David D. Chang

David D. Chang is an American physician-scientist in cancer immunotherapy who co-founded and leads Allogene Therapeutics and, at Kite Pharma, led development of Yescarta, the first CAR T-cell therapy approved for non-Hodgkin lymphoma.

David E. Longnecker

David E. Longnecker is an American physician-anesthesiologist who chaired Anesthesiology at the University of Pennsylvania, led Penn Medicine as corporate chief medical officer, and held national AAMC roles.

David E. Poswillo

David Ernest Poswillo (1927–2003) was a New Zealand-born oral and maxillofacial surgeon and teratologist, professor of oral and maxillofacial surgery at Guy's and St Thomas' Hospitals, London, from 1983 to 1992.