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Denture Precision Attachment
A denture precision attachment is a dental device connecting a partial denture to an abutment tooth's crown, with a female component in the crown and a male component on the denture.
Denture Rebasing
Denture rebasing replaces most or all of an existing denture's acrylic base with new heat-curing resin while keeping the original teeth; distinct from relining, indicated for deteriorated bases with correct occlusion.
Denture Retention
Denture retention: resistance of a removable denture to vertical dislodgement, from saliva film viscosity, base adaptation, border seal, adhesives, or implant attachments. Distinct from denture stability.
Denture, Complete, Immediate
Denture, Complete, Immediate: a complete denture placed immediately after tooth extraction as a temporary functional and cosmetic prosthesis during healing, later replaced by a permanent denture; MeSH term since 1965.
Denture, Complete, Lower
Denture, Complete, Lower: a removable prosthesis replacing all mandibular teeth, tissue-supported only. Mean longevity 8.6 years, poorer stability than upper dentures; two-implant overdenture is the main alternative.
Denture, Complete, Upper
Complete upper denture (maxillary complete denture): removable prosthesis replacing all maxillary teeth, retained by mucosal suction and posterior palatal seal; alternatives include implant overdentures and fixed implant prostheses.
Denture, Partial, Fixed
Denture, Partial, Fixed, also called fixed partial denture, fixed bridge, or FDP/FDP bridge, is a cemented dental prosthesis replacing missing teeth on prepared teeth, roots, or implants; 5-year survival about 94%, 10-year about 89%.
Denture, Partial, Fixed, Resin-Bonded
Resin-bonded fixed partial denture (Maryland bridge, resin-bonded bridge): a minimally invasive fixed dental prosthesis bonded to adjacent teeth with resin cement. 5-year survival about 87.7%; debonding is the main complication.
Denture, Partial, Immediate
Denture, Partial, Immediate (MeSH D003831): a partial denture built before extraction and inserted immediately after removal of the natural teeth, worn during up to 6 months of healing, then replaced by a fitted partial denture.
Denture, Partial, Removable
Removable partial denture (RPD): a patient-removable prosthesis replacing one or more missing teeth in a partially edentulous arch; first documented 1711, clasps from 1746, retention loss the leading complication.
Denture, Partial, Temporary
Denture, Partial, Temporary (interim removable partial denture, flipper): an acrylic partial denture for short-term or emergency tooth replacement until a definitive prosthesis; MeSH D003833, introduced 1965.
Dentures
Dentures (false teeth) are removable acrylic, nylon, or metal appliances replacing missing teeth, complete or partial. Covers fabrication, care, implant-supported alternatives, and history from ancient Egypt to CAD/CAM.
Denufosol
Denufosol (denufosol tetrasodium, INS37217), an inhaled P2Y2 receptor agonist developed by Inspire Pharmaceuticals to hydrate airways in cystic fibrosis; discontinued in 2011 after the TIGER-2 Phase 3 trial failed to confirm lung-function benefit.
Department of Health (Dublin, IE)
The Department of Health (An Roinn Sláinte) is the Irish government department responsible for health policy, established in 1947 and headquartered in Dublin, overseeing bodies including the Health Service Executive.
Department of Health (Philippines)
Department of Health (Kagawaran ng Kalusugan, DOH), the Philippine executive department running national health policy, hospitals, and Universal Health Care implementation; founded 1898, 2026 budget Php 253.8 billion, led by Secretary Edwin Mercado.
Department of Health (Pretoria, ZA)
The National Department of Health is South Africa's government department responsible for the national health system, headquartered in Pretoria and guided by the National Health Act of 2003.
Department of Health (Taipei, TW)
Department of Health, Taipei City Government (臺北市政府衛生局), the city's first-level public health agency with 9 divisions and 6 offices, overseeing Taipei City Hospital and 12 district health centers; reorganized in 2005 and 2017.
Department of Health (Vitoria-Gasteiz, ES)
Department of Health (Departamento de Salud, Osasun Saila) of the Basque Government, headquartered in Vitoria-Gasteiz. It directs Basque health policy and Osakidetza-Servicio Vasco de Salud; minister Alberto Martínez Ruiz since June 2024.
Department of Health and Social Care
The Department of Health and Social Care (DHSC) is the UK government department responsible for England's health and care system, with planned spending of £215.6 billion in 2025-26.
Depatuxizumab mafodotin
Depatuxizumab mafodotin (depatux-m, ABT-414) is AbbVie's anti-EGFR antibody-drug conjugate carrying MMAF, tested in EGFR-amplified glioblastoma; INTELLANCE-1 phase III showed no overall survival benefit and development was discontinued.
Depemokimab
Depemokimab (trade name Exdensur) is a GSK monoclonal antibody that blocks interleukin-5, given twice yearly for severe eosinophilic asthma and chronic rhinosinusitis with nasal polyps.
Dependent personality disorder
Dependent personality disorder (DPD), a Cluster C personality disorder: pervasive need to be taken care of, submissive clinging behavior, fear of separation; five of eight DSM-5-TR criteria; prevalence about 0.5–0.6%; treated with psychotherapy, no approved drugs.
Depersonalization
Depersonalisation, also called depersonalization-derealization disorder (DPD, DPDR, ICD-11 6B66), is a dissociative disorder of feeling detached from one's self; coined 1898, affects 1-2% of the population.
Depersonalization-derealization disorder
Depersonalization-derealization disorder, also known as DPDR, is a dissociative disorder causing persistent feelings of detachment from oneself or one's surroundings, usually triggered by severe stress.
Depolarization
Depolarization is the shift of a cell's membrane potential toward less negative values, mainly via cation influx. Key in action potentials (−70 mV to +30 mV), EPSPs, depolarizing GABA, and spreading depolarization in brain injury.
Deposits on teeth
Deposits on teeth (accretions; ICD-10 K03.6, ICD-11 DA08.4) cover dental calculus or tartar, plaque, materia alba, and stains; calculus is mineralized plaque affecting about 90% of people, removed by scaling.
Deprescribing
Deprescribing is the supervised withdrawal of inappropriate medications to manage polypharmacy; over 40% of adults 75 and older take five or more drugs, and about 50% of older adults take at least one potentially inappropriate medication.
DEPRESS/PHQ-9 study
DEPRESS/PHQ-9 (NCT06702761) is an Al-Nahrain University observational cross-sectional study estimating prevalence and severity of depression among cardiothoracic surgery healthcare workers in Baghdad, Iraq, using the self-administered PHQ-9, with about 200 participants recruited at one Baghdad site from December 2024.
Depressant
Depressant (CNS depressant): a drug class slowing brain activity, also called sedatives or tranquilizers; includes benzodiazepines, barbiturates, and sleep medicines used for insomnia, anxiety, panic attacks, and seizures, with GABA_A mechanisms and overdose risks.
Depression (mood)
Depression (depressive disorder) is a common mental disorder involving persistent depressed mood or loss of interest for at least two weeks; about 322 million people affected, more common in women, treatable with psychotherapy and antidepressants.