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Human health and medicine

25,729 articles

Dequalinium

Dequalinium (dequalinium chloride, Dequadin, Fluomizin) is a bis-quaternary ammonium topical antiseptic used since the 1950s in sore-throat lozenges and, as 10 mg vaginal tablets, for bacterial vaginosis.

Der nervenarzt

Der Nervenarzt (ISSN 0028-2804) is a German-language peer-reviewed journal of neurology and psychiatry founded in 1928, published by Springer Medizin, official DGPPN organ since 1955, editor Frank Schneider.

Der Schmerz

Der Schmerz is a German-language, bimonthly, peer-reviewed pain medicine journal published by Springer since 1987; official organ of the German, Austrian, and Swiss pain societies; ISSNs 0932-433X and 1432-2129.

Derealization

Derealization is the feeling that one's surroundings are unreal, dreamlike, or detached, with intact reality testing; classified with depersonalization as depersonalization/derealization disorder (DPDR), a dissociative disorder affecting about 1 to 2% of people, usually beginning in adolescence, and treated mainly with psychotherapy.

Dermabrasion

Dermabrasion is a surgical skin-resurfacing procedure in which a rotating brush or diamond fraise planes away skin to treat acne scars, wrinkles, and rhinophyma, developed by Abner Kurtin in 1953.

Dermal melanocytosis

Dermal melanocytosis, formerly called Mongolian blue spots, is a benign flat blue or blue-gray birthmark present at birth, usually on the lower back, that fades by early childhood.

Dermatitis

Dermatitis, synonymous with eczema, is inflammation of the skin with spongiotic histology, covering atopic, contact, and seborrhoeic types; treated with emollients, topical corticosteroids, calcineurin inhibitors, biologics, and JAK inhibitors.

Dermatitis herpetiformis

Dermatitis herpetiformis, also called Duhring disease, is a chronic, intensely itchy blistering skin disease caused by IgA deposits and considered the cutaneous manifestation of celiac disease.

Dermatitis of feet

Dermatitis of feet (foot eczema, foot dermatitis) is eczematous inflammation predominantly affecting the feet, most often allergic contact dermatitis from footwear allergens such as rubber chemicals and chromate, distinguished from tinea pedis and psoriasis by patch testing, KOH, and biopsy.

Dermatitis of hands

Dermatitis of hands, or hand eczema, is a common acute or chronic eczematous skin inflammation of the hands and wrists, often occupational, driven by irritants, contact allergy, and atopy, and frequently chronic.

Dermatofibroma

Dermatofibroma (fibrous histiocytoma) is a common benign dermal nodule of spindle fibrocytes, usually under 1 cm on the lower legs, with a dimple sign, central white dermoscopic patch, and FXIIIa-positive/CD34-negative staining.

Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans (DFSP), also called Darier-Ferrand tumor, is a rare low-grade cutaneous sarcoma driven by the t(17;22) COL1A1-PDGFB fusion; treated by Mohs or wide excision, with imatinib for unresectable disease.

Dermatographic urticaria

Dermatographic urticaria, also called symptomatic dermographism or urticaria factitia, is a chronic inducible urticaria in which stroking or scratching the skin produces itchy linear wheals within about 5 minutes, diagnosed by provocation testing and treated with antihistamines.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

Dermatologic Surgery (ISSN 1076-0512) is a monthly peer-reviewed journal founded in 1975 by Perry Robins, official journal of ASDS, American College of Mohs Surgery, ISHRS, and DASIL, published by Wolters Kluwer.

Dermatologic Surgical Procedures

Dermatologic surgical procedures, also called cutaneous or skin surgery, are operative procedures on the skin: biopsy, excision, cryotherapy, laser surgery, dermabrasion, and Mohs micrographic surgery for skin cancer.

Dermatologists

Dermatologists are medical doctors specializing in skin, hair, and nail conditions, trained via residency and board certification (FAAD), with subspecialties like Mohs surgery and dermatopathology, and increasingly using teledermatology.

Dermatology

Dermatology: medical specialty of skin, hair, and nail diseases, over 4,000 conditions, 15-30% of outpatient care; covers history, global burden (4.69 billion GBD 2021 cases), diagnostic accuracy, dermoscopy, and teledermatology.

Dermatology Life Quality Index

The Dermatology Life Quality Index (DLQI) is a 10-question questionnaire measuring the impact of skin disease on quality of life, published in 1994 by Finlay and Khan.

Dermatome (anatomy)

Dermatome (anatomy): area of skin innervated by one spinal dorsal root, mapped by Keegan and Garrett (1948) and Foerster (1933); adjacent dermatomes overlap, and maps guide radiculopathy and spinal cord injury localization.

Dermatomyositis

Dermatomyositis (DM), an idiopathic inflammatory myopathy, causes proximal muscle weakness with Gottron papules and heliotrope rash; defined by type I interferon signature, myositis-specific autoantibodies, cancer risk, and 2026 FDA approval of brepocitinib.

Dermatopathia pigmentosa reticularis

Dermatopathia pigmentosa reticularis (DPR), allelic to Naegeli-Franceschetti-Jadassohn syndrome, is a rare autosomal dominant KRT14 ectodermal dysplasia with reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy.

Dermatophagia (φαγεία)

Dermatophagia (φαγεία), also called dermatodaxia or wolf-biting, is a compulsive body-focused repetitive behavior of biting one's own skin, usually around the fingers, classified under obsessive-compulsive and related disorders and treated with habit reversal therapy.

Dermatophytosis of nail

Dermatophytosis of nail (tinea unguium, dermatophytic onychomycosis, ICD-11 1F28.1) is a dermatophyte fungal nail infection, mostly Trichophyton rubrum, causing 90% of toenail cases; treated with terbinafine or azoles.

Dermatoses of infancy

Dermatoses of infancy (ICD-11 EH40) are skin diseases of infants from birth to about 2 years, including infantile seborrhoeic dermatitis, napkin dermatoses, erythrodermas, and acute haemorrhagic oedema of infancy.

Dermatosparaxis Ehlers-Danlos syndrome

Dermatosparaxis Ehlers-Danlos syndrome (dEDS, EDS type VIIC, OMIM 225410) is an ultra-rare autosomal recessive ADAMTS2-related EDS with extreme skin fragility, lax skin, bruising, and hieroglyphic collagen fibrils on electron microscopy.

Dermochondrocorneal dystrophy

Dermochondrocorneal dystrophy, or François syndrome (OMIM 221800), is an extremely rare childhood-onset disorder combining skin nodules, hand and foot osteochondrodystrophy, and corneal opacities; fewer than 20 patients reported, inheritance uncertain, no gene identified.

Dermographism

Dermographism is a skin condition in which firm stroking or scratching produces raised red lines within minutes, the most common form of chronic inducible urticaria, first treated with antihistamines.

Dermoid cyst

The dermoid cyst, also known as a mature teratoma or benign cystic teratoma, is a benign ovarian germ cell tumor that commonly contains tissue from all three germ layers.

Dermoscopy

Dermoscopy, also called dermatoscopy or epiluminescence microscopy, is a noninvasive technique using a magnifying illuminated device to visualize subsurface skin structures and detect melanoma earlier.

Dersimelagon

Dersimelagon (MT-7117) is an investigational oral selective MC1R agonist by Tanabe Pharma, now LEO Pharma, for EPP and XLP phototoxicity; positive phase 2 and INSPIRE phase 3 trials, FDA NDA under Priority Review.