25,729 articles
Eranda Paka
Eranda Paka (Eraṇḍa pāka) is an official Ayurvedic semisolid avaleha confection of castor (Ricinus communis) cooked with milk, sugar, ghee, and herbs, from Yogratnakara, AFI Part II 3:3, dose 5–15 g, used for Vata disorders and constipation.
ERAS trial
ERAS trial (NCT05511194): single-blind randomized trial of a modified Enhanced Recovery After Surgery protocol for pediatric complicated appendicitis in Guadalajara, Mexico; 40 children; shorter stay (3.15 vs 5.20 days) without added morbidity.
ERAS-0015
JYP0015 (ERAS-0015, JYP-0015) is an oral pan-RAS molecular glue from Guangzhou JOYO Pharma, licensed to Erasca, in Phase 1/2 trials for RAS-mutant pancreatic, lung, and colorectal cancers.
ERAS-4001
ERAS-4001 is Erasca's oral pan-KRAS inhibitor, in-licensed from Medshine Discovery, that binds mutant and wild-type KRAS while sparing HRAS/NRAS; it is in the BOREALIS-1 Phase 1 trial (NCT07021898) for KRAS-mutant solid tumors, with monotherapy data expected in H2 2026.
Erasmus Darwin
Erasmus Darwin (1731–1802), English physician, poet, inventor, and Lunar Society founder; grandfather of Charles Darwin. Proposed evolution from 'one living filament' in Zoonomia (1794–96) and wrote The Botanic Garden; declined George III as patient.
Erasmus MC
Erasmus MC (Erasmus University Medical Center Rotterdam) is the university medical center of Erasmus University Rotterdam, formed in 2002-2003 from Dijkzigt Hospital, Sophia Children's Hospital, the Daniel den Hoed Clinic, and the medical faculty; the Netherlands' largest medical research center.
Eratrectinib
Anrotinib (Willcell TRK inhibitor) denotes eratrectinib (安瑞曲替尼, VC004, brand Weimaituo), Jiangsu Vcare's next-generation pan-TRKA/B/C inhibitor for NTRK fusion solid tumors, conditionally approved in China June 2026 at 50 mg twice daily.
Eravacycline
Eravacycline (Xerava) is a fully synthetic fluorocycline tetracycline antibiotic approved in 2018 for complicated intra-abdominal infections in adults, dosed 1 mg/kg IV every 12 hours, with activity against multidrug-resistant Gram-negative bacteria but not cUTI.
Erb's palsy
Erb paralysis (Erb's palsy, Erb-Duchenne paralysis) is upper-arm weakness from C5–C6 upper trunk brachial plexus injury, mostly at birth; ~90% of neonatal brachial plexus palsies, often with shoulder dystocia, usually recovering in 3–4 months.
Ercha Shangqing Pills
Ercha Shangqing Wan (儿茶上清丸, Jingmen Shangqing Wan) is a Category 1.1 innovative traditional Chinese medicine pill by Hubei Qijin Pharmaceutical, approved January 2024 (Z20240001) for mild recurrent aphthous ulcers with upper-jiao heat syndrome.
Erdafitinib
Erdafitinib (Balversa) is an oral pan-FGFR kinase inhibitor for metastatic urothelial carcinoma with susceptible FGFR3 alterations after prior therapy including a PD-1/PD-L1 inhibitor; THOR showed survival benefit over chemotherapy.
Erdheim–Chester disease
Erdheim-Chester disease (ECD), a rare clonal non-Langerhans histiocytic neoplasm first described in 1930, causes foamy histiocyte infiltration of bones and organs, with BRAF V600E mutations in 50-60% and MAPK-inhibitor therapy.
Erdong Tang
二冬汤 (Erdong Tang) is a Qing-era classic Chinese medicine formula from Cheng Guopeng's Yixue Xinwu, built on tian dong and mai dong, for upper-wasting diabetes; approved as Erdong Tang granules, a 2024 category-3.1 new drug.
Erdosteine
Erdosteine, a thiol-based mucoactive prodrug (N-(carboxymethylthioacetyl)-homocysteine thiolactone) activated to metabolite M1, treats acute and chronic pulmonary disease; RESTORE showed reduced COPD exacerbation rate and duration.
Erectile dysfunction
Erectile dysfunction (ED, impotence): persistent inability to achieve or maintain an erection sufficient for sexual activity. Affects up to 52% of men aged 40–70; vasculogenic in up to 80% of cases; treated first with PDE5 inhibitors (sildenafil, tadalafil).
Erection
Erection (penile erection, tumescence): hardening and enlargement of the penis as blood fills the corpora cavernosa, driven by nitric oxide and nervous-system signals; three types, ED when impaired.
Erection Hardness Score
Erection Hardness Score (EHS, also EHGS): single-item patient-reported 0-4 scale of penile rigidity developed in 1998 for sildenafil trials, validated 2007 by Mulhall et al., used as an adjunct ED outcome measure.
Erector spinae plane block
The erector spinae plane block, or thoracic erector spinae plane block, is a regional anesthesia technique that anesthetizes thoracic spinal nerves for perioperative and chronic pain relief.
ERES trial
ERES trial (NCT04124172): Institut Guttmann pilot randomized triple-blind study of 1 Hz rTMS plus rehabilitation versus sham rTMS for paretic upper-limb function in subacute stroke, 24 planned participants.
Erethism
Erethism (erethism mercurialis, mad hatter syndrome) is a neuropsychiatric syndrome of chronic mercury poisoning: shyness, irritability, memory loss, insomnia. Linked to mercuric nitrate in 19th-century hat felt making; term coined by John Pearson in 1805.
Erfonrilimab
Erfonrilimab (KN046, 依瑞利单抗), a PD-L1 x CTLA-4 bispecific antibody from Jiangsu Alphamab, in phase III trials (ENREACH-L-01 squamous NSCLC, ENREACH-PDAC-01 pancreatic cancer); phase II ORR 46% in first-line metastatic NSCLC.
ERG rearrangement analysis
ERG rearrangement analysis is a molecular diagnostic test that detects ERG gene rearrangements, most often the TMPRSS2–ERG fusion, to support prostate cancer diagnosis and risk stratification.
Ergocalciferol
Ergocalciferol (vitamin D2), a fat-soluble vitamin made by UV irradiation of ergosterol in yeast, used for vitamin D deficiency, hypoparathyroidism, and refractory rickets; raises serum 25(OH)D less than cholecalciferol (D3).
Ergometry
Ergometry is a diagnostic method measuring cardiopulmonary responses during controlled exercise on a treadmill or bicycle ergometer, used to diagnose coronary artery disease and prescribe exercise training.
Ergonomics
Ergonomics, also known as human factors, is the science of how people interact with systems, applied to design that maximizes human well-being and overall system performance.
Ergospirometry
Ergospirometry, also called cardiopulmonary exercise testing (CPET), is a diagnostic method that measures respiratory gas exchange and ventilation during graded exercise to quantify cardiopulmonary fitness and identify exercise-limiting mechanisms.
Eribulin
Eribulin (Halaven, eribulin mesylate) is a synthetic halichondrin B analogue microtubule inhibitor chemotherapy. FDA-approved 2010 for pretreated metastatic breast cancer and liposarcoma; EMBRACE trial showed 13.1 vs 10.6 months median survival.
Eric Topol
Eric Topol, American cardiologist and geneticist, Executive Vice-President of Scripps Research and founder of its Translational Institute; Vioxx critic, AI-in-medicine author of Deep Medicine and Super Agers, led the UK Topol Review.
Erik Brodt
Erik Brodt is an Ojibwe family physician and health-equity researcher at OHSU who founded the Northwest Native American Center of Excellence and joined the National Academy of Medicine in 2021.
Eritoran
Eritoran (E5564) is a synthetic lipid A analog and TLR4 antagonist that binds the MD-2 hydrophobic pocket; developed by Eisai for severe sepsis, it was safe but failed to reduce mortality in phase 2 and phase 3 ACCESS trials.