25,729 articles
2009 swine flu pandemic
2009 swine flu pandemic (H1N1pdm09): first flu pandemic in 40 years, detected in California April 2009, WHO phase 6 June 2009, over 214 countries affected, ended August 2010, virus now seasonal.
2010 Sahel food crisis
The 2010 Sahel food crisis was a food emergency in West Africa that put over 10 million people at risk of hunger after poor 2009 rains.
2010 Zamfara lead poisoning
The 2010 Zamfara lead poisoning was a mass outbreak of childhood lead poisoning in Zamfara State, northern Nigeria, caused by artisanal gold ore processing, killing more than 400 children.
2011 Le Roy, New York illness outbreak
The 2011 Le Roy, New York illness outbreak: tics among 18 students at Le Roy Junior-Senior High School, diagnosed as mass psychogenic illness after environmental and PANDAS theories were excluded; all recovered.
2012 Sahel food crisis
The 2012 Sahel food crisis was a food emergency affecting over 18 million people across West and Central Africa, the region's fourth crisis in seven years.
2015–16 Zika virus epidemic
The 2015–16 Zika virus epidemic: spread of Zika virus (ZIKV) from Brazil across the Americas via Aedes aegypti mosquitoes, causing microcephaly and Guillain-Barré syndrome; WHO declared a PHEIC on 1 February 2016, ended 18 November 2016.
2016 Angola yellow fever outbreak
The 2016 Angola yellow fever outbreak, which began in Luanda in December 2015, was Angola's largest recorded yellow fever epidemic, with 884 confirmed cases and 381 deaths.
2023 Paris bedbug infestation
The 2023 Paris bedbug infestation (punaises de lit) was a media-driven panic over Cimex lectularius around Paris Fashion Week; nearly 50 reported transit sightings were unverified, and Russian disinformation amplified the alarm before the 2024 Olympics.
2023–2026 mpox epidemic
2023–2026 mpox epidemic, also called the clade Ib mpox upsurge: global mpox outbreak beginning with clade Ib emergence in eastern DRC in September 2023, PHEIC declared August 2024, ended September 2025, with 187,117 confirmed cases and 510 deaths reported 2022–2026.
2024 Laos methanol poisoning
2024 Laos methanol poisoning: November 2024 mass methanol poisoning in Vang Vieng, Laos, from tainted vodka at Nana Backpackers Hostel, killing six foreign tourists (two Australian, British, American, two Danish) and hospitalizing about 11 others.
2026 Ebola epidemic
2026 Ebola epidemic: Bundibugyo virus disease outbreak beginning in Ituri, DRC, April 2026; DRC's 17th Ebola outbreak, spread to Uganda, France, Germany; WHO PHEIC 17 May 2026; second largest Ebola outbreak on record, ~9,500 cases, CFR ~48%.
2026 Kent meningitis outbreak
2026 Kent meningitis outbreak: MenB invasive meningococcal disease cluster in Canterbury, England, March 2026, linked to Club Chemistry and the University of Kent; 21 confirmed cases, 2 deaths, ST-485 P1.12-1,16-183 strain, antibiotics and targeted vaccination response.
2045 Initiative
2045 Initiative (Россия 2045), transhumanist project founded February 2011 by Russian entrepreneur Dmitry Itskov in Moscow; Avatar A–D roadmap to mind uploading and cybernetic immortality by 2045, disputed by neuroscientists and behind schedule.
20p13 microdeletion syndrome
20p13 microdeletion syndrome (20p subtelomeric deletion syndrome, Del(20)(p13), monosomy 20p13) is a rare chromosomal anomaly with developmental delay, mild to moderate intellectual disability, epilepsy, dysmorphic signs, and candidate genes SOX12, NRSN2, TBC1D20, CSNK2A1.
20q11.2 microdeletion syndrome
20q11.2 microdeletion syndrome (Del(20)(q11.2), Monosomy 20q11, ORPHA:444051) is a rare chromosomal microdeletion disorder causing syndromic intellectual disability, hypotonia, feeding difficulties, hand and foot anomalies, and craniofacial dysmorphism, with GDF5, EPB41L1, and SAMHD1 as candidate genes.
21q deletion syndrome
21q deletion syndrome (partial 21q monosomy, monosomy 21, ORPHA:574) is a rare chromosomal disorder from loss of part of chromosome 21q; under 50 reported cases, severity driven by 21q22 involvement, RUNX1 deletions causing thrombocytopenia and leukemia risk.
22q11.2 duplication syndrome
22q11.2 duplication syndrome, or 22q11.2 microduplication syndrome, is a rare autosomal dominant chromosomal anomaly: an extra ~3-Mb copy at 22q11.2 causing highly variable heart, urogenital, palatal, and neurodevelopmental features, often mild or silent.
22Rv1
22Rv1 (CWR22Rv1) is a human prostate carcinoma cell line from the relapsed CWR22R xenograft; androgen receptor positive, androgen-independent, PSA-secreting, AR-V7 expressing, wild-type TP53, and an XMRV-producing castration-resistant prostate cancer model.
2D echocardiography
2D echocardiography is an ultrasound method producing real-time cross-sectional views of the beating heart; it is the first-line cardiac imaging test, inexpensive, portable, and non-invasive.
2p15p16.1 microdeletion syndrome
2p15p16.1 microdeletion syndrome (Del(2)(p15p16.1), OMIM 612513) is a rare contiguous gene deletion disorder on chromosome 2p causing intellectual disability, microcephaly, hypotonia, and facial dysmorphism; candidate genes XPO1, USP34, BCL11A, REL.
2p21 microdeletion syndrome
2p21 microdeletion syndrome (Del(2)(p21), hypotonia-cystinuria type 1) is an autosomal recessive contiguous gene deletion disorder at 2p21 involving SLC3A1, PREPL, PPM1B, and C2orf34, causing cystinuria, neonatal seizures, hypotonia, severe developmental delay, and lactic acidemia.
2q23.1 microdeletion syndrome
2q23.1 microdeletion syndrome, also called pseudo-Angelman syndrome or MBD5 haploinsufficiency, is a rare chromosomal disorder caused by deletion at 2q23.1 on chromosome 2, causing intellectual disability, speech impairment, seizures, and sleep and behavior problems.
3-hydroxy-3-methylglutaryl-CoA synthase deficiency
3-hydroxy-3-methylglutaryl-CoA synthase deficiency (HMGCS2 deficiency, mitochondrial HMG-CoA synthase deficiency) is a rare autosomal recessive ketogenesis defect causing hypoketotic hypoglycemia, vomiting, and hepatomegaly during fasting or illness, treatable with glucose.
3-hydroxyisobutyric aciduria
3-hydroxyisobutyric aciduria (OMIM 236795) is a rare autosomal recessive organic aciduria of valine metabolism, marked by urinary 3-hydroxyisobutyric acid, ketoacidosis, dysmorphism, and variable severity; cause often unresolved.
3-methylcrotonyl-CoA carboxylase deficiency
3-methylcrotonyl-CoA carboxylase deficiency (3-MCC deficiency, 3-methylcrotonylglycinuria, MCCD) is an autosomal recessive leucine metabolism disorder caused by MCCC1 or MCCC2 mutations, with very low penetrance: most affected people stay asymptomatic, a few have metabolic crises treated with carnitine and fasting avoidance.
3-methylglutaconic aciduria type 1
3-methylglutaconic aciduria type 1 (MGCA1, OMIM #250950), or 3-methylglutaconyl-CoA hydratase deficiency, is a rare autosomal recessive AUH-gene leucine catabolism disorder with highly elevated urinary 3-methylglutaconic acid, variable neurologic severity, and newborn screening by C5-OH acylcarnitine.
3-methylglutaconic aciduria type 4
3-methylglutaconic aciduria type 4 (MGCA4, MGA4, OMIM 250951) is a heterogeneous, unclassified autosomal recessive metabolic category with mild or intermittent urinary 3-methylglutaconic acid excretion, defined by excluding 3-MGA types I-III, with SUCLA2, POLG1, TMEM70, and RYR1 subgroups and no specific treatment.
3-methylglutaconic aciduria-neonatal cataract-neurologic involvement-congenital neutropenia syndrome
3-methylglutaconic aciduria type 7 (MGA7, MEGCANN, CLPB deficiency), ORPHA:445038, is a rare autosomal recessive CLPB-related metabolic disorder with 3-methylglutaconic aciduria, cataract, neutropenia, and progressive neurologic disease, onset antenatal or neonatal.
3-Methylmethcathinone
3-Methylmethcathinone (3-MMC, metaphedrone) is a synthetic cathinone stimulant, positional isomer of mephedrone, first seen in Sweden in 2012, a dopamine-selective monoamine releaser with no medical use, controlled in the EU and many countries.
3C syndrome
3C syndrome, or Ritscher-Schinzel syndrome (cranio-cerebello-cardiac dysplasia), is a rare congenital malformation syndrome with craniofacial, cerebellar, and cardiac defects, caused by WASHC5, CCDC22, or VPS35L variants, inherited autosomal or X-linked recessively.