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Allan Beigel
Allan Beigel was an American psychiatrist and University of Arizona vice president who built a unified community mental health system in Pima County and led national psychiatric organizations.
ALLEGRO-2b/3 trial
ALLEGRO-2b/3 (NCT03732807), Pfizer's pivotal phase 2b/3 trial of ritlecitinib (PF-06651600, Litfulo) for severe alopecia areata in patients 12 and older; 718 randomized, SALT ≤20 primary endpoint at week 24.
Allen Carr
Allen Carr (1934–2006), British accountant and author of The Easy Way to Stop Smoking, creator of the drug-free Easyway quit-smoking method; quit a 100-a-day habit in 1983 and built a global clinic network.
Allen J. Dietrich
Allen J. Dietrich (1947–2024) was an American family medicine researcher at Dartmouth, elected to the Institute of Medicine in 1996 for improving preventive care in primary practices.
Allen S. Lichter
Allen S. Lichter is an American radiation oncologist who was dean of the University of Michigan Medical School and chief executive officer of ASCO from 2006 to 2016.
Allen Whipple
Allen Oldfather Whipple (1881–1963) was an American surgeon at Columbia University who gave his name to the Whipple procedure for pancreatic tumors and described Whipple's triad for diagnosing insulinoma.
Allen's test
Allen's test (modified Allen test, MAT): bedside maneuver assessing radial and ulnar artery patency and palmar arch collateral circulation before radial artery puncture, cannulation, or harvest; color should return within 5–15 seconds; pooled sensitivity 57%, specificity 91%.
Allergan
Allergan plc, Irish pharmaceutical maker of Botox, Juvéderm, and Restasis, acquired by AbbVie on May 8, 2020 for $63 billion; its aesthetics business continues as Allergan Aesthetics, an AbbVie company.
Allergen
Allergen: a foreign substance, usually a protein, triggering allergic reactions; term coined by Clemens von Pirquet in 1906; IgE-mediated sensitization and elicitation; WHO/IUIS nomenclature; FDA major food allergens.
Allergen immunotherapy
Allergen immunotherapy treats allergy by giving gradually increasing doses of pollen, dust mite, or venom, modifying the immune response; a course lasts 3 to 5 years.
Allergic bronchopulmonary aspergillosis
Allergic bronchopulmonary aspergillosis (ABPA) is an allergic lung disease in which the immune system reacts to Aspergillus fumigatus colonizing the airways, most often in people with asthma or cystic fibrosis.
Allergic conjunctivitis
Allergic conjunctivitis, also called ocular allergy (SAC, PAC, VKC, AKC, GPC), is IgE-mediated mast-cell inflammation of the conjunctiva causing itchy, watery, red eyes; treated stepwise with avoidance, dual-action antihistamine drops, and immunotherapy.
Allergic contact blepharoconjunctivitis
Allergic contact blepharoconjunctivitis, also called contact blepharoconjunctivitis, is a delayed hypersensitivity reaction of the eyelid skin and conjunctiva, typically triggered by cosmetics, metals, or eye drops.
Allergic contact dermatitis
Allergic contact dermatitis (ACD, contact allergy) is a type IV delayed T-cell-mediated eczema appearing 24–72 hours after skin contact with an allergen such as nickel; diagnosed by patch testing, affecting about 20% of the population.
Allergic contact dermatitis due to topical medicaments
Allergic contact dermatitis due to topical medicaments (medicament contact allergy) is type IV hypersensitivity to topical antibiotic, corticosteroid, anesthetic, or vehicle ingredients, led by bacitracin and neomycin, diagnosed by patch testing.
Allergic contact urticaria
Allergic (immunologic) contact urticaria, ICD-11 EK10, is an IgE-mediated immediate wheal-and-flare reaction after skin contact with proteins or haptens such as latex and foods, potentially spreading to anaphylaxis; diagnosed by prick testing and specific IgE, treated by avoidance.
Allergic gingivitis
Allergic gingivitis (アレルギー性歯肉炎), ICD-11 DA0B.0, is gum inflammation from hypersensitivity to dental materials, toothpaste flavorings, or foods; diagnosed by patch testing and confirmed by resolution after allergen removal.
Allergic rhinitis
Allergic rhinitis (hay fever) is an IgE-mediated nasal inflammation from inhaled allergens, affecting about 400 million people, often with asthma; treated with intranasal corticosteroids, antihistamines, saline, and allergen immunotherapy.
Allergic rhinitis due to pollen
Allergic rhinitis due to pollen, or hay fever, is an IgE-mediated seasonal nasal allergy to tree, grass, and ragweed pollen. Distinguished from perennial rhinitis by seasonality; treated with intranasal corticosteroids, antihistamines, and immunotherapy.
Allergy
Allergy: immunologically initiated hypersensitivity, mainly IgE-mediated type I reactions. Covers Gell–Coombs types, mast-cell degranulation, allergens, diagnosis, immunotherapy, and omalizumab's 2024 approval for food allergy.
Allergy to cats
Allergy to cats, or cat dander allergy, is an IgE-mediated reaction mainly to the Fel d 1 protein from cat saliva and skin glands; managed by avoidance, HEPA filtration, medications, and allergen immunotherapy.
Allied health professions
Allied health professions: health occupations other than medicine, dentistry, and nursing, including physiotherapy, radiography, occupational therapy, and paramedicine; regulated by protected titles or scope-of-practice laws, with large workforces in the NHS, Australia, and India.
Allisartan isoproxil
Allisartan isoproxil (阿利沙坦酯, Xinlitang) is China's first domestically developed class 1.1 ARB antihypertensive, dosed 240 mg daily, activated to EXP3174 by gut esterases, marketed by Shenzhen Salubris since 2013.
Allocation concealment
Allocation concealment is the safeguard in a randomized controlled trial that keeps upcoming treatment assignments hidden from those enrolling participants until allocation is irrevocable, preventing selection bias.
ALLOCORD
ALLOCORD (HPC, Cord Blood), BLA 125413 from SSM Cardinal Glennon Children's Medical Center, is an FDA-licensed allogeneic cord blood hematopoietic progenitor cell therapy approved May 30, 2013 for unrelated donor transplantation and hematopoietic reconstitution.
Allodynia
Allodynia, also called touch-evoked pain, is pain from a stimulus that does not normally provoke pain, defined by the IASP. Distinct from hyperalgesia, it arises through peripheral and central sensitization in neuropathic pain, fibromyalgia, and migraine.
Allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen dsat
StrataGraft (allogeneic cultured keratinocytes and dermal fibroblasts in murine collagen-dsat) is Stratatech's FDA-approved 2021 bioengineered skin substitute for adult deep partial-thickness thermal burns, later wound down by Mallinckrodt in 2024.
Allogeneic cultured keratinocytes and fibroblasts in bovine collagen
Allogeneic cultured keratinocytes and fibroblasts in bovine collagen (Gintuit) is a two-layer cell-sheet biologic, BLA 125400, FDA approved March 9, 2012 for mucogingival conditions in adults; first FDA-approved cell-based product, discontinued in 2014.
Allogeneic hematopoietic stem cell transplantation
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) infuses donor stem cells to replace diseased bone marrow, treating blood cancers and marrow disorders, with graft-versus-host disease as its main risk.
Alloimmune haemolytic anaemia
Alloimmune hemolytic anemia is anemia caused by antibodies from another individual destroying red blood cells, arising most often through transfusion, pregnancy, or transplantation, and including disease of the fetus and newborn.