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Human health and medicine

25,729 articles

Hand-foot-genital syndrome

Hand-foot-genital syndrome (HFGS, hand-foot-uterus syndrome, OMIM 140000) is a rare autosomal dominant HOXA13 disorder with short thumbs and great toes plus urogenital defects; fertility is normal.

Hand-held dynamometry

Hand-held dynamometry is a clinical method in which a portable force gauge held against a limb measures peak isometric muscle strength, widely used in rehabilitation and neuromuscular assessment.

Hand–eye coordination

Hand–eye coordination (eye–hand coordination, EHC): using visual information to guide manual movements like reaching and grasping. Defined by sequential visual-to-motor processing, posterior parietal control, tests such as the Purdue Pegboard, and reliability ICCs of 0.80–0.94.

Hand, foot, and mouth disease

Hand, foot, and mouth disease (HFMD), also called hand-foot-and-mouth disease, is a contagious enterovirus illness (EV-A71, CV-A16, CV-A6) of children under 5, causing fever, mouth sores, and hand and foot rash; usually mild, rarely severe.

Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen

Handchirurgie, Mikrochirurgie, plastische Chirurgie (HaMiPla) is a German peer-reviewed bimonthly journal of hand, micro-, and plastic surgery, published by Thieme since 1982, organ of DAH, DGH, ÖGH, DAM, and DGPRÄC, ISSN 0722-1819.

Handedness

Handedness, or hand preference, is the tendency to favor one hand for tasks; about 10.6% of people are left-handed, with the roughly 1:10 right-left ratio shaped by evolution and moderated by culture.

Handgrip strength test

The handgrip strength test measures maximal squeezing force with a dynamometer, used as a quick bedside proxy for overall muscle function and to screen for sarcopenia and frailty.

Handjob

Handjob: slang for manual sex, hand stimulation of a partner's penis; counterpart fingering on a vulva. Slang attested from 1937; no pregnancy risk; lower STI exposure than penetrative sex; gloves and handwashing reduce risk.

HandtherRCT trial

HandtherRCT (NCT01215760) was a University of São Paulo randomized trial of early mirror-therapy sensory re-education versus delayed classic re-education after median or ulnar nerve repair; 20 analyzed patients showed no Rosen Score difference.

Hangnail

Hangnail: torn dry skin at the edge of a fingernail (not nail), from dryness, biting, or wet work; treated by soaking and clipping, risking paronychia if ripped; from Middle English agnail.

Hangover

A hangover, also called veisalgia, is the set of mental and physical symptoms felt the day after heavy drinking, starting as blood alcohol returns to zero.

Hanoi Medical University

Hanoi Medical University (Trường Đại học Y Hà Nội), founded 1902 as the Indochina Medical School, is Vietnam's oldest public medical university in Hanoi, offering a six-year Vietnamese-language Doctor of Medicine degree and large postgraduate training.

Hans Asperger

Hans Asperger (1906–1980) was an Austrian pediatrician who headed the therapeutic pedagogy ward of the Vienna University Children's Clinic and described "autistic psychopathy" in 1944, giving Asperger syndrome its name.

Hans Rosling

Hans Rosling (1948–2017), Swedish physician and Karolinska professor of international health; co-founded Gapminder, created Trendalyzer data visualizations, named konzo, gave famous TED talks, and wrote Factfulness.

Hansoh CDH17 antibody-drug conjugate (licensed to Roche)

HS-20110 is Hansoh Pharma's CDH17-targeting antibody-drug conjugate with a topoisomerase inhibitor payload, in Phase I trials for colorectal cancer; Roche licensed worldwide rights (excluding Greater China) for US$80 million upfront plus up to US$1.45 billion in milestones.

Hantavirus infection

Hantavirus infection, or hantavirus disease, is rodent-borne illness from Hantaviridae viruses, causing HPS/HCPS in the Americas and HFRS in Europe and Asia; Andes virus alone spreads person to person.

Hantavirus pulmonary syndrome

Hantavirus pulmonary syndrome (HPS, also HCPS) is a severe rodent-borne respiratory disease of the Americas caused by New World hantaviruses such as Sin Nombre and Andes virus, first recognized in the 1993 Four Corners outbreak, with roughly 38% fatality and no specific treatment.

Hao-Fountain syndrome

Hao-Fountain syndrome (HAFOUS, OMIM 616863), also called USP7-related neurodevelopmental disorder, is a rare autosomal dominant disorder caused by USP7 variants or 16p13.2 microdeletion, marked by developmental delay, speech delay, autism, hypotonia, and dysmorphic features.

Haphephobia

Haphephobia, also called aphephobia or chiraptophobia, is a rare specific phobia of being touched, diagnosed under DSM-5 and ICD-11 (6B03), treated mainly with exposure therapy.

Haploidentical bone marrow transplantation

Haploidentical bone marrow transplantation is a form of allogeneic stem cell transplantation using a half-HLA-matched relative, available to the roughly 70% of patients lacking a fully matched sibling donor.

Haploidentical hematopoietic cell transplantation

Haploidentical hematopoietic cell transplantation (haplo-HCT) is an allogeneic stem cell transplant using a half-matched family donor to treat hematologic diseases, available to over 95% of patients.

Haploidentical stem cell transplantation

Haploidentical stem cell transplantation is a form of stem cell transplant in which the donor, almost always a family member, shares exactly half of the recipient's HLA antigens.

Haptocorrin

Haptocorrin (R-binder, transcobalamin I, TCN1) is a 60–70 kDa salivary glycoprotein that binds vitamin B12, protects it from stomach acid, and carries 70–80% of circulating B12 to the liver.

Haptocorrin deficiency

Haptocorrin deficiency (transcobalamin I deficiency, TCI deficiency, OMIM 193090) is a rare benign autosomal recessive cobalamin transport disorder causing low serum B12 with normal MMA, homocysteine, and no symptoms.

Harald Loe

Harald Loe, also known as Harald A. Löe, was a Norwegian-born dental researcher, a founder of modern periodontology, and director of the US National Institute of Dental Research.

Haratala bhasma

Haratala bhasma (Haratal Bhasma) is an Ayurvedic Rasashastra medicine: purified orpiment (arsenic trisulfide, As2S3) incinerated into a fine ash, used internally and externally after Shodhana, with classical doses of 30-60 mg.

Harbin Medical University

Harbin Medical University (哈尔滨医科大学, HMU) is a medical university in Harbin, China, founded in 1926 by Wu Liande and merged with the Red Army Medical School lineage; known for cardiovascular research and affiliated hospitals.

HARBOR trial

The HARBOR trial was a 24-month, phase 3 clinical trial of ranibizumab in 1,097 patients with neovascular age-related macular degeneration, run at 100 sites from 2009 to 2012.

Harbour BioMed BCMA×CD3 bispecific T-cell engager (licensed to Otsuka)

HBM7020, a BCMA×CD3 bispecific T-cell engager from Harbour BioMed's HBICE/Harbour Mice platforms, uses a 2+1 format to deplete BCMA-positive B cells; NMPA IND cleared 2023, licensed ex-Greater China to Otsuka in June 2025 for autoimmune disease.

Hard corn

Hard corn (heloma durum, clavus) is the most common corn type: a circumscribed hyperkeratotic lesion with a hard central keratin core on toe bony prominences, caused by friction and pressure, treated by paring, salicylic acid, and footwear change.