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Human health and medicine

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Ambrisentan

Ambrisentan (Letairis, Volibris) is an oral, ETA-selective endothelin receptor antagonist approved in 2007 for pulmonary arterial hypertension WHO FC II-III; once-daily 5-10 mg dosing, low liver toxicity, edema risk, REMS removed 2025.

Ambroxol

Ambroxol, a mucolytic metabolite of bromhexine marketed since 1973, thins airway mucus and shows anti-inflammatory, antioxidant, surfactant-stimulating, and local anesthetic actions; studied for COPD, sore throat, and Gaucher/Parkinson disease.

Ambulance

Ambulance: emergency vehicle providing medical care and patient transport, from BLS to ALS units. Covers ALS vs BLS outcomes, response-time evidence, Anglo-American and Franco-German models, and history from Larrey to Freedom House.

Ambulatory blood pressure

Ambulatory blood pressure (ABPM): 24-hour cuff-based out-of-office blood pressure measurement during daily life. Reference standard for confirming hypertension; distinguishes white-coat from masked hypertension; daytime threshold 135/85 mmHg.

Ambulatory care

Ambulatory care, also called outpatient care, is medical care for patients not formally admitted to a hospital bed, ranging from physician offices to surgery centers.

Ambulatory electrocardiography

Ambulatory electrocardiography (AECG) records the heart's electrical activity over hours to years while patients follow their usual routines, using portable devices such as Holter monitors to detect intermittent arrhythmias.

Ambulatory monitoring

Ambulatory monitoring is the recording of physiological signals, chiefly blood pressure, ECG, and activity, during patients' daily lives, using ABPM, Holter and patch recorders, and implantable loop devices.

Ambulatory Surgical Procedures

Ambulatory surgical procedures, also called outpatient or same-day surgery, are operations without overnight hospitalization, performed in ASCs or hospital outpatient departments; Medicare's CY 2026 rule phases out the inpatient-only list and expands the ASC covered procedures list.

Amcenestrant

Amcenestrant (SAR439859) is Sanofi's oral selective estrogen receptor degrader for ER-positive breast cancer; its AMEERA program failed phase 2/3 endpoints and development was discontinued in August 2022.

Amcinonide

Amcinonide (Cyclocort) is a synthetic topical corticosteroid, C28H35FO7, approved in the US in 1979, used as 0.1% cream, ointment, and lotion for corticosteroid-responsive dermatoses.

AMD-SNP study

AMD-SNP (NCT02248324) is a Turkish multicenter observational case-control study testing whether verified AMD gene polymorphisms, including CFH rs1061170, ARMS2 rs10490924, and HTRA1 rs11200638, associate with AMD in 2,800 patients and 2,200 controls.

Amdinocillin

Amdinocillin, also called mecillinam, is an amidinopenicillin antibiotic binding PBP2, active against Gram-negative bacteria; oral prodrug pivmecillinam (Selexid, Pivya) treats urinary tract infections.

Amdinocillin pivoxil

Amdinocillin pivoxil (pivmecillinam; Pivya, Selexid) is the oral prodrug of mecillinam, an amidinopenicillin targeting penicillin-binding protein-2, used for uncomplicated urinary tract infections; FDA-approved in the US in April 2024 at 185 mg three times daily.

Amdokitug (SSGJ-608)

Amdokitug (SSGJ-608, 安沐奇塔单抗, brand Yisaituo) is Sunshine Guojian's humanized anti-IL-17A IgG1κ monoclonal antibody, NMPA-approved 13 February 2026 for moderate-to-severe plaque psoriasis, with spondylitis trials ongoing.

Amelia Mangay-Maglacas

Dr Amelia Mangay-Maglacas is a Filipino public-health nurse-scientist who worked at the World Health Organization on nursing's role in primary health care and infection control.

Ameloblastic carcinoma

Ameloblastic carcinoma (ICD-O 9270/3) is a rare malignant odontogenic jaw tumor combining ameloblastoma-like histology with cytologic atypia; most common odontogenic malignancy, mandible-predominant, treated by resection.

Ameloblastoma

Ameloblastoma: rare benign but locally aggressive odontogenic jaw tumor (80% mandible), WHO 2022 five variants, BRAF V600E-driven, treated surgically; conservative surgery recurs about three times more often than radical resection.

Amelocerebrohypohidrotic syndrome

Amelocerebrohypohidrotic syndrome, or Kohlschütter-Tönz syndrome (OMIM 226750), is a rare autosomal recessive disorder combining amelogenesis imperfecta, infantile epilepsy, and intellectual decline, caused mainly by ROGDI and sometimes SLC13A5 mutations.

Amelogenesis imperfecta

Amelogenesis imperfecta (AI), congenital enamel hypoplasia, is a hereditary group of enamel development disorders causing discolored, sensitive, worn teeth; prevalence 1:700 to 1:14,000, over 20 causative genes, treated with early restorative dental care.

Amenamevir

Amenamevir (ASP2151, Amenalief) is a helicase-primase inhibitor antiviral discovered by Astellas, approved in Japan for herpes zoster at 400 mg once daily for 7 days, marketed by Maruho; development outside Japan was suspended in 2011.

Amenorrhea

Amenorrhea is the absence of menstrual periods, primary (never began by age 15) or secondary (stopped 3+ months). Causes include PMOS/PCOS, hyperprolactinemia, thyroid disease, hypogonadism, and anatomic defects; workup starts with pregnancy test, FSH, prolactin, TSH.

Amenorrhoea

Amenorrhoea (amenorrhea), ICD-11 GA20.0, is the absence of menstruation, primary (never began) or secondary (stopped). Affects about 3–4% of reproductive-age women; pregnancy is the most common cause of the secondary form.

American Academy of Dermatology

The American Academy of Dermatology (AAD) is a professional medical society of dermatologists founded in 1938 and based in Rosemont, Illinois, with more than 21,000 members worldwide.

American Academy of Neurology

American Academy of Neurology (AAN), professional society of neurologists founded 1948 by A.B. Baker, headquartered in Minneapolis; 40,000+ members, publishes Neurology and Continuum, sets expert-witness and conduct standards, and advocates for brain health.

American Academy of Ophthalmology

The American Academy of Ophthalmology, or AAO, is the largest professional association of ophthalmologists in the United States, incorporated as an independent organization in 1979.

American Academy of Otolaryngology — Head and Neck Surgery

The American Academy of Otolaryngology — Head and Neck Surgery (AAO-HNS) is a professional society for ear, nose, and throat surgeons, founded in 1896 with about 13,000 members.

American Academy of Sleep Medicine

The American Academy of Sleep Medicine is a United States professional society for sleep medicine practitioners, founded in 1975, with over 11,000 members and 2,300 accredited sleep centers.

American Association For Cancer Research

American Association for Cancer Research (AACR), founded May 7, 1907, in Washington, D.C.; Philadelphia-based nonprofit with 65,000+ members, ten journals including Cancer Research, and the annual Cancer Progress Report advocating federal cancer research funding.

American Association for Clinical Chemistry

American Association for Clinical Chemistry (AACC), US professional society founded 1948 in New York; renamed Association for Diagnostics & Laboratory Medicine (ADLM) July 23, 2023; publisher of Clinical Chemistry; over 70,000 members.

American Association for Respiratory Care

American Association for Respiratory Care (AARC), formerly Inhalation Therapy Association, is the professional association for respiratory therapists, founded 1946 in Chicago, based in Addison, Texas, publisher of Respiratory Care journal.