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Logotherapy
Logotherapy, also called meaning-centered therapy, is a psychotherapy developed by Austrian psychiatrist Viktor Frankl, based on the idea that people are primarily motivated by a will to meaning.
Loha bhasma
Loha bhasma (Lauha bhasma), Ayurvedic calcined iron ash made by shodhana and repeated puta incineration, yielding magnetite-group iron oxide nanoparticles; a hematinic used for iron deficiency anemia (Pandu roga), dose 30–240 mg.
Loha Parpati
Loha Parpati (लोह पर्पटी), an Ayurvedic Rasa Shastra medicine: Lauha Bhasma (calcined iron) triturated into Kajjali and cast into thin flakes, used as a haematinic; documented in Rasapaddhati, no API monograph.
Lohasava
Lohasava (लोहासव, Lohasavam) is a fermented Ayurvedic iron tonic from the 14th-century Sarangadhara Samhita, combining purified iron with Trikatu, Triphala, honey, and jaggery; used for anemia (Pandu roga) and weak digestion, dosed 15–30 ml twice daily.
Loiasis
Loiasis, also known as African eye worm, is a parasitic disease caused by the roundworm Loa loa and spread by day-biting deerflies in Central and West Africa.
Loin
Loin: the body region on either side of the lower spine between ribs and pelvis, also a cut of meat. From Latin lumbus via Old French loigne; source of lumbar, sirloin, and loin pain.
Loin pain-hematuria syndrome
Loin pain-hematuria syndrome (LPHS), also called loin pain haematuria syndrome, is a rare diagnosis of exclusion combining severe flank pain with hematuria, first described in 1967, affecting mostly young women, with contested physical versus somatoform origins.
Lokanatha rasa
Lokanatha Rasa (Lakanatha rasa), a classical Ayurvedic mercurial preparation from Rasendra Sara Sangraha for liver and spleen disorders; contains Kajjali plus Abhra, Lauha, Thamra, Varatika bhasmas; mercury bound as HgS.
Lomefloxacin
Lomefloxacin, sold as Maxaquin, is a fluoroquinolone antibiotic approved in the United States in 1992 to treat bronchitis and urinary tract infections, later discontinued and known for phototoxicity.
Lomilomi massage
Lomilomi (Lomi Lomi), traditional Hawaiian massage rooted in oral family healing traditions; defined in HRS §452-1 as kneading, stroking, and pressing of the body; certified historically by Hawaii's Board of Massage, with scant lomilomi-specific clinical research.
Lomitapide
Lomitapide (Juxtapid, Lojuxta) is an oral microsomal triglyceride transfer protein inhibitor approved in 2012 as adjunct LDL-C-lowering therapy for homozygous familial hypercholesterolemia; LDLR-independent, with GI and hepatic steatosis risks.
Lonafarnib
Lonafarnib (Zokinvy, SCH 66336) is an oral farnesyltransferase inhibitor, the first approved treatment for Hutchinson-Gilford progeria syndrome and processing-deficient progeroid laminopathies, FDA-approved 2020 and EU-approved 2022, extending survival about 2.5 years.
Lonapegsomatropin
Lonapegsomatropin (Skytrofa, TransCon hGH) is a once-weekly transiently pegylated somatropin prodrug that releases unmodified human growth hormone over about 25 hours; approved for pediatric growth hormone deficiency in the US (2021), EU (2022), and China (2026), and for adults in the US (2025).
Loncastuximab tesirine
Loncastuximab tesirine, sold as Zynlonta and developed as ADCT-402, is a CD19-targeted antibody–drug conjugate linking a monoclonal antibody to the PBD dimer SG3199, FDA-approved in 2021 for relapsed or refractory large B-cell lymphoma.
Long COVID
Long COVID (post COVID-19 condition): chronic multisystem illness after SARS-CoV-2 infection lasting 3+ months; 200+ symptoms including PEM, brain fog, POTS; no biomarker or validated cure; ~400 million cumulative cases, ~$1 trillion annual economic impact.
Long labour
Long labour (prolonged labour, labour dystocia; ICD-11 JB03) is childbirth lasting longer than average from contraction onset to placental delivery, a leading indication for primary cesarean section, managed by partograph monitoring and oxytocin or amniotomy augmentation.
Long protocol (ovarian stimulation)
The long protocol is an IVF ovarian stimulation regimen in which a GnRH agonist starts in the mid-luteal phase, suppressing the pituitary before gonadotropin stimulation.
Long QT syndrome
Long QT syndrome (LQTS), also Romano-Ward or Jervell and Lange-Nielsen syndrome, is an inherited or drug-induced cardiac channelopathy with prolonged QT interval, torsades de pointes, syncope, and sudden death risk.
Long-Acting Reversible Contraception
Long-acting reversible contraception (LARC): IUDs and subdermal implants, the most effective reversible birth control, over 99% effective, lasting years, reversible on removal.
Long-course chemoradiotherapy
Long-course chemoradiotherapy, also called long-course chemoradiation, is a neoadjuvant treatment for locally advanced rectal cancer combining about five to six weeks of pelvic radiotherapy with fluoropyrimidine chemotherapy before surgery.
Long-Term Care
Long-term care (LTC) is ongoing medical, personal, and support services for people with lasting physical or cognitive limitations, delivered at home, in community settings, and in residential facilities.
Long-Term Care Insurance
Long-term care insurance (LTCI) covers extended help with daily living at home, in assisted living, or in nursing homes, since Medicare does not pay for it; a shrunken U.S. private market of a few insurers sells stand-alone and hybrid policies.
Long-term depression
Long-term depression (LTD) is a long-lasting weakening of synaptic transmission induced by prolonged low-frequency stimulation, mainly via AMPA receptor internalization; key forms are NMDAR-dependent and mGluR-dependent LTD, studied in hippocampus and cerebellum.
Long-term effects of cannabis
The long-term effects of cannabis are the persistent health consequences of repeated use, including doubled psychosis risk in heavy users, cannabis use disorder, and cognitive harm from adolescent use.
Long-term oxygen therapy
Long-term oxygen therapy (LTOT) is the supervised use of supplemental oxygen, typically at home, for at least 15 hours daily in chronic severe hypoxemia, mainly from COPD.
Long-term potentiation
Long-term potentiation (LTP), originally called long-lasting potentiation, is a long-lasting increase in synaptic strength after brief high-frequency stimulation, first reported by Bliss and Lømo in 1973.
Longevity
Longevity is the duration of human life, measured by life expectancy and healthy life expectancy. Global life expectancy reached 73.3 years in 2024; genetics accounts for about 25 percent of lifespan variation.
Longevity claims
Longevity claims: assertions that interventions extend human lifespan or healthspan. Exercise has RCT support for healthspan; no human RCT shows lifespan extension; supplements, peptides, and reprogramming claims lack evidence and draw FTC and FDA scrutiny.
Longuemare Consultants
Longuemare Consultants Inc. is a consulting firm overseen by R. Noel Longuemare, an electrical engineer who spent 41 years at Westinghouse and served in the Pentagon from 1993 to 1997.
Lonidamine
Lonidamine is an anticancer drug that disrupts energy metabolism in tumor cells; introduced in 1979 as an antispermatogenic agent, it was approved in Italy to potentiate cancer therapy.