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Lung ultrasonography
Lung ultrasonography is a bedside imaging method using ultrasound at the chest wall to diagnose pleural effusion, consolidation, interstitial syndrome, and pneumothorax without ionizing radiation.
Lung ultrasound
Lung ultrasound is a bedside, artifact-based imaging method detecting pleural effusion, consolidation, pneumothorax, and interstitial syndrome; its BLUE protocol diagnoses acute respiratory failure causes with 90.5% accuracy.
Lung ultrasound score
The lung ultrasound score is a bedside score that grades aeration loss across 12 chest regions, summing grades of 0 to 3 into a total of 0 to 36.
Lung Volume Measurements
Lung volume measurements determine absolute lung gas volumes (FRC, RV, TLC) by body plethysmography, multiple breath washout, helium dilution, or imaging, standardized in the 2023 ERS/ATS technical statement updating 2005.
Lung volume reduction surgery
Lung volume reduction surgery (LVRS) is an operation for severe emphysema in which the most damaged 20–35% of each lung is removed to ease breathing.
Lunge (exercise)
Lunge (exercise): a unilateral lower-body strength exercise stepping forward, backward, or sideways; works quadriceps, hamstrings, glutes, and adductors; over 40 variations; higher quadriceps and hamstring activation than the squat.
Lunsotogene parvec cwha
Lunsotogene parvec-cwha (Otarmeni, formerly DB-OTO) is Regeneron's dual AAV1 gene therapy delivering OTOF to inner hair cells, FDA accelerated-approved April 23, 2026 for biallelic OTOF-related severe-to-profound hearing loss.
Lupin Limited (लुपिन लिमिटेड)
Lupin Limited (लुपिन लिमिटेड), Mumbai-headquartered Indian multinational pharmaceutical company founded 1968 by Desh Bandhu Gupta; major generics, biosimilars, and respiratory drug maker, 3rd largest by prescriptions in the U.S. market.
Lupus
Lupus, or systemic lupus erythematosus (SLE), is a chronic autoimmune disease affecting skin, joints, kidneys, and other organs, mainly women aged 15 to 44, classified by ANA entry plus weighted 2019 EULAR/ACR criteria and treated with hydroxychloroquine, glucocorticoids, immunosuppressives, and biologics.
Lupus and pregnancy
Lupus and pregnancy (SLE in pregnancy): higher maternal and fetal risks than the general population, driven by active disease, lupus nephritis, and antiphospholipid antibodies; managed with preconception remission, aspirin, and multidisciplinary monitoring.
Lupus anticoagulant
Lupus anticoagulant (LA) is an antiphospholipid antibody, usually IgG against beta2-glycoprotein I or prothrombin, that prolongs clotting tests in vitro yet promotes thrombosis in vivo; it is a key laboratory criterion for antiphospholipid syndrome, detected by dRVVT and aPTT, and easily confounded by anticoagulant drugs.
Lupus anticoagulant-hypoprothrombinaemia syndrome
Lupus anticoagulant-hypoprothrombinaemia syndrome (LAHS, LAHPS) is a rare acquired disorder combining lupus anticoagulant with antibody-mediated factor II deficiency, causing bleeding in 89% of cases, thrombosis in 13%, treated first-line with corticosteroids.
Lupus erythematosus
Lupus erythematosus, including systemic lupus erythematosus (SLE), discoid, drug-induced, and neonatal forms, is a chronic autoimmune disease attacking skin, joints, kidneys, and other organs, affecting women about nine to ten times more than men.
Lupus erythematosus panniculitis
Lupus erythematosus panniculitis (LEP, lupus profundus) is a rare chronic cutaneous lupus subtype inflaming subcutaneous fat, causing painful indurated nodules, lipoatrophy, lobular lymphocytic panniculitis with hyaline necrosis, treated first with antimalarials.
Lupus nephritis
Lupus nephritis is kidney inflammation from systemic lupus erythematosus, diagnosed by biopsy with ISN/RPS classification, treated with glucocorticoids plus MPAA, cyclophosphamide, belimumab, or calcineurin inhibitors per KDIGO 2024.
Lurasidone
Lurasidone (Latuda) is an atypical antipsychotic approved for schizophrenia (2010) and bipolar I depression (2013), dosed 40-160 mg/day with food, with a favorable metabolic profile versus olanzapine and quetiapine.
Lurbinectedin
Lurbinectedin (Zepzelca, PM01183), a trabectedin analog DNA minor groove binder inhibiting oncogenic transcription; FDA accelerated approval June 15, 2020 for metastatic SCLC after platinum chemotherapy, plus 2025 atezolizumab maintenance approval.
Lurie Children's Hospital
Ann & Robert H. Lurie Children's Hospital of Chicago, founded 1882 by Julia Foster Porter, is Illinois' largest pediatric Medicaid provider in Streeterville, with 266,000+ patients yearly, Stanley Manne Research Institute, and top U.S. News and Newsweek 2026 rankings.
Luscan-Lumish syndrome
Luscan-Lumish syndrome, also called SETD2-related overgrowth syndrome (OMIM 616831), is a rare autosomal dominant disorder caused by SETD2 variants, featuring macrocephaly, postnatal overgrowth, obesity, developmental delay, autism, seizures, and Chiari I malformation.
Luspatercept
Luspatercept (REBLOZYL, ACE-536) is an erythroid maturation agent, an activin receptor IIB-Fc fusion protein binding TGF-beta ligands, approved 2019 for anemia in beta thalassemia and myelodysplastic syndromes, dosed 1 mg/kg subcutaneously every 3 weeks.
Lusutrombopag
Lusutrombopag (Mulpleta, Mulpleo), an oral thrombopoietin receptor agonist approved in 2018, raises platelet counts in adults with chronic liver disease before invasive procedures; 3 mg daily for 7 days, main risk thrombosis.
Luteal phase
Luteal phase: the post-ovulatory half of the menstrual cycle, when the corpus luteum secretes progesterone; normally 11–17 days. Covers luteal phase deficiency (≤10 days), its contested diagnosis, and IVF luteal support.
Luteinizing hormone
Luteinizing hormone (LH, ICSH, lutropin) is an anterior pituitary gonadotropin with alpha and beta subunits that drives gonadal steroidogenesis, the midcycle ovulation surge, and testosterone production, and is measured in fertility testing.
Luteinizing hormone test
The luteinizing hormone test is a blood or urine measurement of LH, a pituitary hormone, used to time ovulation, assess fertility, and diagnose puberty and pituitary disorders.
Lutembacher's syndrome
Lutembacher's syndrome: coexistence of atrial septal defect (congenital or iatrogenic) and mitral stenosis (usually rheumatic). Named for René Lutembacher's 1916 account; treated by percutaneous balloon mitral valvuloplasty plus ASD device closure.
Lutetium oxodotreotide
Lutathera (lutetium (177Lu) oxodotreotide, lutetium Lu 177 dotatate) is a radiolabeled somatostatin analog for SSTR-positive GEP-NETs; EU approval 2017, US 2018, dosed 7.4 GBq every 8 weeks for four cycles.
Lutikizumab
Lutikizumab (ABT-981), AbbVie's dual-variable domain antibody neutralizing IL-1α and IL-1β; failed osteoarthritis phase 2 trials but positive phase 2 hidradenitis suppurativa results, now in phase 3.
Lutropin alfa
Lutropin alfa (Luveris) is recombinant human luteinizing hormone made in CHO cells, approved in the EU in 2000 and by FDA in 2004 for follicular development with FSH in women with severe LH deficiency (LH < 1.2 IU/l).
Luvometinib tablets
Luvometinib tablets (芦沃美替尼片, Fumaiming, FCN-159) is Fosun Pharma's oral MEK1/2 inhibitor, a Chinese class 1 drug approved May 2025 for adult LCH/histiocytic neoplasms and pediatric NF1 plexiform neurofibromas.
Luye rivastigmine multi-day transdermal patch
Luye rivastigmine multi-day transdermal patch (LY30410, RID-TDS, RIVALUEN LA) is a twice-weekly rivastigmine patch for mild to moderate Alzheimer's dementia, bioequivalent to the daily Exelon patch and approved in Europe, Japan, and China.