25,729 articles
Neomycin/polymyxin B/bacitracin
Neomycin/polymyxin B/bacitracin, or triple antibiotic ointment (Neosporin), is an OTC first aid antibiotic ointment with bacitracin zinc 400 units, neomycin 3.5 mg, and polymyxin B 5,000 units per gram for minor wounds.
Neonatal acne
Neonatal acne (baby acne, neonatal cephalic pustulosis): a common self-limiting newborn rash affecting about 20% of newborns around 2 weeks of age, linked to Malassezia yeast, not true acne, clearing without scarring.
Neonatal adrenoleukodystrophy
Neonatal adrenoleukodystrophy (NALD), also called intermediate Zellweger spectrum disorder, is an autosomal recessive peroxisome biogenesis disorder (PEX genes, OMIM 202370) marked by hypotonia, leukodystrophy, hearing and vision loss, VLCFA accumulation, and adrenal atrophy.
Neonatal alloimmune neutropenia
Neonatal alloimmune neutropenia (NAIN, also FNAIN) is a rare newborn neutropenia caused by maternal IgG antibodies against paternal human neutrophil antigens (HNA), mainly HNA-1a/1b; self-limiting, incidence below 0.1%, treated with antibiotics and G-CSF.
Neonatal antiphospholipid syndrome
Neonatal antiphospholipid syndrome, also known as Neonatal Hughes syndrome, is a rare autoimmune disorder in which newborns develop venous or arterial blood clots with antiphospholipid antibodies.
Neonatal aspergillosis
Neonatal aspergillosis (ICD-11 KA63.1) is invasive Aspergillus infection of newborns, mainly extremely preterm infants; usually cutaneous, nosocomial, caused by A. fumigatus or A. flavus, treated with liposomal amphotericin B.
Neonatal aspiration syndromes
Neonatal aspiration syndromes (ICD-11 KB26), also called neonatal aspiration of meconium, blood, amniotic fluid, or milk, are newborn lung injuries from aspirated material causing inflammation, surfactant inactivation, respiratory distress, and often PPHN.
Neonatal brainstem dysfunction
Neonatal brainstem dysfunction is a rare neurologic disorder of newborns marked by impaired suction and swallowing, obstructive apnea, medication-resistant gastroesophageal reflux, and cardiac vagal overactivity with bradycardia.
Neonatal candidosis
Neonatal candidosis, or neonatal candidiasis, is Candida infection of newborns, mainly preterm and very low birth weight infants in NICUs. Key species are C. albicans, C. parapsilosis, and emerging C. auris; treated with amphotericin B or fluconazole.
Neonatal cardiac failure
Neonatal cardiac failure (KB40, ICD-11) is heart failure in newborns: insufficient cardiac output for metabolic demands, caused mainly by structural congenital heart disease, cardiomyopathy, arrhythmia, anemia, and asphyxia, treated with diuretics, inotropes, mechanical support, or transplantation.
Neonatal cerebral ischaemia
Neonatal cerebral ischaemia (ICD-11 KB00; ICD-10 P91.0) is insufficient cerebral blood flow in newborns, subdivided into perinatal arterial stroke and neonatal sinovenous thrombosis; NAIS causes about 80% of perinatal strokes.
Neonatal cerebral sinovenous thrombosis
Neonatal cerebral sinovenous thrombosis (CSVT) is venous thrombosis of cerebral veins or dural sinuses in newborns, causing seizures and encephalopathy, with 2.6 to 12 cases per 100,000 term neonates yearly and controversial anticoagulation treatment.
Neonatal cold injury syndrome
Neonatal cold injury syndrome (ICD-11 KD12.0) is accidental severe newborn hypothermia below 35°C from cold exposure, causing apathy, poor feeding, edema, and often death; prevented by WHO warm-chain thermal care.
Neonatal compartment syndrome
Neonatal compartment syndrome (NCS, neonatal limb compartment syndrome) is a rare newborn condition of raised pressure in a limb compartment, usually the forearm, marked by a sentinel skin lesion; early fasciotomy gives the lowest sequelae rate.
Neonatal dermatomyositis
Neonatal dermatomyositis (Neonatal DM) is a rare autoimmune disorder of the newborn period causing widespread muscle weakness, severe hypotonia, diminished reflexes, and highly elevated creatine kinase.
Neonatal hemochromatosis
Neonatal hemochromatosis (NH), now largely termed gestational alloimmune liver disease (GALD), is severe neonatal liver failure with extrahepatic iron deposition, caused by maternal IgG against fetal hepatocytes; recurrent but preventable with antenatal IVIG.
Neonatal hydrocephalus
Neonatal hydrocephalus, also called infantile or congenital hydrocephalus, is excess cerebrospinal fluid in a newborn's brain ventricles with raised pressure; causes include prematurity-related hemorrhage, infection, and L1CAM and other genetic forms, treated by shunt or ETV.
Neonatal hypertension
Neonatal hypertension: elevated newborn blood pressure, defined as systolic or diastolic BP at or above the 95th percentile for postmenstrual age on three occasions. Affects 0.2% of term infants, up to 3% in NICU; usually secondary to renal disease, umbilical catheter thrombosis, or chronic lung disease.
Neonatal hypoglycaemia
Neonatal hypoglycaemia, low blood glucose in newborns during the first days of life, affects about 40% of neonates below 2.6 mmol/L; transitional hyperinsulinism, risk screening, dextrose gel treatment, and neurodevelopmental outcomes distinguish it.
Neonatal hypomagnesaemia
Neonatal hypomagnesaemia (ICD-10 P71.2, ICD-11 KB61.0) is a transient newborn disorder with serum magnesium below 0.66 mmol/L, caused by maternal diabetes, prematurity, or renal and intestinal losses, and producing functional hypoparathyroidism and hypocalcemia.
Neonatal hypotension
Neonatal hypotension is abnormally low blood pressure in newborns, mainly preterm infants, affecting about 50% of VLBW babies in the NICU; no standard definition exists, and dopamine, dobutamine, and hydrocortisone are main treatments.
Neonatal ichthyosis-sclerosing cholangitis syndrome
NISCH syndrome, also called ILVASC or IHSC, a very rare autosomal recessive CLDN1-related ichthyosis syndrome with neonatal ichthyosis, scalp hypotrichosis, scarring alopecia, and sclerosing cholangitis; 37 cases reported.
Neonatal intensive care unit
Neonatal intensive care unit (NICU): specialized hospital unit for critically ill or preterm newborns, first established 1960 at Yale by Louis Gluck; AAP levels II–IV, US admission 9.8% of births in 2023.
Neonatal intrahepatic cholestasis due to citrin deficiency
NICCD (neonatal intrahepatic cholestasis caused by citrin deficiency) is the neonatal phenotype of autosomal recessive SLC25A13/citrin deficiency, causing cholestasis, hypercitrullinemia, and hypoglycemia in infants, treated with lactose-free MCT-enriched formula and fat-soluble vitamins.
Neonatal iodine exposure
Neonatal iodine exposure (ORPHA:238688, ICD-10 P72.2) is a rare endocrine disorder causing transient hypothyroidism, mainly in preterm newborns, after topical povidone-iodine antiseptics, iodinated contrast media, amiodarone, or maternal iodine excess, via the Wolff-Chaikoff effect.
Neonatal jaundice
Neonatal jaundice, or neonatal hyperbilirubinemia, is yellow skin and eye discoloration from bilirubin buildup in newborns, affecting over 80% of infants; treated with phototherapy or exchange transfusion to prevent kernicterus.
Neonatal listeriosis
Neonatal listeriosis is newborn infection with Listeria monocytogenes, usually acquired in utero, presenting as early-onset sepsis or pneumonia or late-onset meningitis, rare but with high mortality and disability risk.
Neonatal lupus erythematosus
Neonatal lupus erythematosus, or neonatal lupus, is an autoimmune condition of fetuses and newborns caused by maternal anti-Ro antibodies crossing the placenta, causing rash and heart block.
Neonatal meningitis
Neonatal meningitis: bacterial infection of the meninges and CSF in newborns (first 28 days, often considered to 90 days). Caused mainly by GBS, E. coli, Listeria; fatality 10–15% in high-income versus 40–58% in low-income settings.
Neonatal milia
Neonatal milia (milk spots) are benign keratin-filled white cysts present at birth in 40-50% of full-term newborns, mainly on the nose and face, resolving spontaneously within weeks without treatment; oral forms are Epstein pearls and Bohn nodules.