Human health and medicine

SATWAVPP trial

SATWAVPP (NCT04716868): Mexican randomized double-blind trial comparing Agave tequilana blue-variety fructans (Predilife) with psyllium plantago for functional constipation; 79 patients, 8 weeks, similar responder rates across four arms.

Saul A. Rosenberg

Saul A. Rosenberg was an American medical oncologist at Stanford University who, with radiologist Henry Kaplan, developed the first curative treatments for Hodgkin lymphoma and founded the nation's first Division of Medical Oncology.

Saul J. Farber

Saul J. Farber, also known as Saul Joseph Farber, was an American nephrologist who chaired NYU's Department of Medicine from 1966 to 2000 and served as its dean.

Savant syndrome

Savant syndrome, also called autistic savant skills, is a rare condition in which an 'island of genius' contrasts with overall disability; about one in 10 autistic people have savant abilities, in domains like music, art, and calendar calculating.

SAVE trial (NCT00738179)

SAVE trial (NCT00738179), Sleep Apnea cardioVascular Endpoints study, McEvoy et al NEJM 2016; randomized trial of CPAP in 2,717 nonsleepy OSA patients with cardiovascular disease; CPAP did not reduce cardiovascular events (HR 1.10) but improved sleepiness and quality of life.

SAVIOR trial

SAVIOR (NCT04745390) is a Phase III randomized Canadian trial comparing standard-dose SBRT (2000 cGy in 5 fractions) with radiobiologically-guided dose-selected SBRT in primary or secondary liver carcinoma, enrolling 110 patients.

Savolitinib

Savolitinib (volitinib, AZD6094, HMPL-504; Orpathys) is an oral, selective ATP-competitive MET tyrosine kinase inhibitor approved in China (2021) for MET exon 14-skipping NSCLC and developed with osimertinib for MET-amplified EGFR-mutant NSCLC and gastric cancer.

Saw palmetto extract

Saw palmetto extract (Serenoa repens, Sabal serrulata), from dwarf palm berries, is a dietary supplement promoted for BPH urinary symptoms, hair loss, and prostatitis; large trials and the 2023 Cochrane review find little to no benefit, with mild side effects.

Saxagliptin anhydrous

Saxagliptin anhydrous (BMS-477118, CAS 361442-04-8) is the anhydrous form of saxagliptin, a DPP-4 inhibitor for type 2 diabetes marketed as the monohydrate; FDA approved 2009 as Onglyza, with increased heart failure hospitalization risk in SAVOR-TIMI 53.

Oct 20, 2026

SBRT-NSCLC trial

SBRT-NSCLC (NCT00870116) was a French prospective, non-randomized, multicentric trial sponsored by Centre Leon Berard comparing CyberKnife SBRT, linac SBRT, and conformal radiotherapy in 120 patients with non-operated T1-T2N0M0 NSCLC, with 2-year local control as the primary endpoint.

Sc-1

Sc-1 (CVCL_1888, synonym Scott) is a human follicular lymphoma cell line established in 1977 from the ascites of a 67-year-old man; EBV-negative, t(8;14;18), BCL2-IGH positive, DSMZ ACC-558.

Scabies

Scabies (Sarcoptes scabiei var. hominis infestation), also called the itch or Norwegian scabies in crusted form, is a contagious mite infestation causing intense nocturnal itching, affecting about 200 million people worldwide, treated with permethrin or ivermectin.

Scale for the Assessment of Positive Symptoms

The Scale for the Assessment of Positive Symptoms (SAPS) is a clinician-rated interview measuring positive psychotic symptoms in schizophrenia, published by Nancy Andreasen at the University of Iowa in 1984.

Scalene muscles

Scalene muscles (scalenus anterior, medius, posterior): three paired lateral neck muscles from cervical vertebrae to ribs 1-2; flex the neck, elevate ribs as accessory respiratory muscles, and bound the interscalene triangle carrying the brachial plexus and subclavian artery.

Scalp

Scalp: the five-layer soft tissue covering the skull (skin, connective tissue, galea aponeurotica, loose areolar tissue, pericranium, mnemonic SCALP), supplied by five paired arteries and trigeminal plus cervical nerves; site of hair growth, dandruff, and alopecia.

Scalp dysaesthesia

Scalp dysaesthesia (scalp dysesthesia), a chronic neurocutaneous condition of scalp itching, burning, and pain without skin findings; diagnosis of exclusion linked to cervical spine disease, psychiatric comorbidity, and neuropathic mechanisms.

Scalp folliculitis

Scalp folliculitis, ICD-11 EG30.0, is inflammation of scalp hair follicles, usually bacterial (Staphylococcus aureus, Cutibacterium acnes); its severe chronic scarring form is folliculitis decalvans with tufted hairs and permanent hair loss.

Scalp nerve block

A scalp nerve block is a regional anesthesia technique injecting local anesthetic around the scalp's sensory nerves, used for craniotomy pain and to blunt the hemodynamic response to skull pin fixation.

Scalp psoriasis

Scalp psoriasis is psoriasis affecting the scalp, causing well-defined red plaques with silvery scale and flaking that resembles dandruff. It affects about 80% of people with psoriasis.

Scalp reconstruction

Scalp reconstruction is the set of surgical techniques for closing scalp defects, using primary closure, skin grafts, local flaps, tissue expansion, or free tissue transfer, chosen by defect size.

SCALP syndrome

SCALP syndrome is a rare neurocutaneous condition combining a sebaceous nevus, aplasia cutis congenita, an ocular limbal dermoid, and a giant congenital melanocytic nevus with seizures and other brain defects.

Scalp-ear-nipple syndrome

Scalp-ear-nipple syndrome (Finlay-Marks syndrome, SEN syndrome, OMIM 181270) is a rare autosomal dominant ectodermal dysplasia caused by KCTD1 mutations, marked by scalp aplasia cutis, malformed ears, and absent or rudimentary nipples.

Scalpel

A scalpel, also known as a surgical knife, is a small, thin instrument of separate blade and handle used for surgical incisions, among the oldest tools in surgery.

SCAN-B study

SCAN-B (Sweden Cancerome Analysis Network - Breast), NCT02306096, is a population-based prospective Swedish breast cancer study started in 2010 in Lund, using RNA sequencing of tumors from over 20,000 enrolled patients, with molecular subtyping clinically implemented in Skåne.

Scandinavian Simvastatin Survival Study

Scandinavian Simvastatin Survival Study (4S), 1994 Lancet trial of simvastatin in 4,444 Nordic coronary heart disease patients; first statin trial to show 30% lower all-cause mortality versus placebo over 5.4 years.

Scanning laser ophthalmoscopy

Scanning laser ophthalmoscopy (SLO) is an ophthalmic imaging method that builds a video image of the retina with a scanning laser, using about 1/1000 of the light of conventional ophthalmoscopy.

Scanning Laser Polarimetry

Scanning laser polarimetry (SLP, GDx) is a noninvasive eye imaging method measuring retinal nerve fiber layer thickness via polarization retardation of a 780 nm laser, used mainly for glaucoma diagnosis and monitoring.

Scaphoid bone

The scaphoid bone, also called the hand navicular or os scaphoideum, is a boat-shaped carpal bone on the thumb side of the wrist and the most commonly fractured carpal bone.

Scaphoid fracture

Scaphoid fracture: break of the scaphoid (navicular) carpal bone of the wrist, usually from a fall on an outstretched hand. Most common carpal fracture; poor retrograde blood supply risks nonunion and avascular necrosis; treated by casting or screw fixation.