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STAMP trial (NCT04048161)
STAMP trial (NCT04048161), Study of Tacrolimus vs Mycophenolate Mofetil in Pediatric Patients With Nephrotic Syndrome: Chinese multicenter RCT in 270 children with FRNS/SDNS; tacrolimus gave 82.22% vs 58.52% 1-year relapse-free survival (JAMA Pediatrics 2025).
STAMPEDE trial
STAMPEDE (Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy) is a UK-Swiss multi-arm multi-stage platform trial, 2005-2023, ~12,000 men, showing docetaxel, abiraterone, and low-burden radiotherapy improve survival when added to hormone therapy.
Standard for the Uniform Scheduling of Medicines and Poisons
The Standard for the Uniform Scheduling of Medicines and Poisons (SUSMP), or Poisons Standard, is Australia's national instrument under section 52D of the Therapeutic Goods Act 1989 classifying medicines and poisons into ten Schedules, from Pharmacy Medicine to prohibited substances, with decisions given effect by state and territory law.
Standard precautions
Standard precautions are the minimum infection prevention practices applied to every patient in every healthcare setting, regardless of infection status, set out by the CDC in 1996.
Standard triple therapy
Standard triple therapy is a Helicobacter pylori eradication regimen combining a proton pump inhibitor with amoxicillin and clarithromycin twice daily, now recommended only where clarithromycin resistance is low.
Standardized patient simulation
Standardized patient simulation is a medical education method in which trained people portray patients realistically and repeatably so learners can practice and be assessed on clinical skills.
Standardized rate
A standardized rate is a disease or mortality rate adjusted to a reference age structure, allowing fair comparison of populations; it includes directly standardized rates and SMRs.
Standing Orders
Standing orders are written, pre-authorized medical instructions allowing nurses, pharmacists, and other non-physician staff to deliver tests, treatments, or vaccinations when patients meet defined criteria, without a physician order at the time of care.
Standing Position
Standing position: the upright, orthostatic human posture supported only by the feet (MeSH D000078783, 2019). Covers its anatomy, evolutionary origin, and health effects of prolonged occupational standing.
Stanford Medicine
Stanford Medicine is Stanford University's integrated academic health system: the School of Medicine, Stanford Health Care, and Stanford Children's Health. Founded from Cooper Medical College (1858), it moved to Palo Alto in 1959 and pioneered US heart transplantation.
Stanley Baum
Stanley Baum was an American radiologist at the University of Pennsylvania and one of the first interventional radiologists in the United States, chairing Penn's radiology department from 1975 to 1996.
Stanley Medical College
Stanley Medical College (SMC), Chennai, a government medical college established July 2, 1938 and affiliated with Tamil Nadu Dr. M.G.R. Medical University, with 250 MBBS seats, Government Stanley Hospital, and noted hand surgery and transplant programs.
Stannosis
Stannosis, also called tin pneumoconiosis or tin miners' lung, is a benign non-fibrotic pneumoconiosis from chronic inhalation of tin oxide (SnO, SnO2) dust or fume, causing dense 2-4 mm lung radiopacities without fibrosis; first described by Beintker in 1944.
Stannsoporfin
Stannsoporfin, also called tin mesoporphyrin (SnMP) or Stanate, is a heme oxygenase inhibitor developed by InfaCare and Mallinckrodt as a single-injection adjunct to phototherapy for neonatal hyperbilirubinemia; it lowered bilirubin in phase 2b trials but was never FDA approved and development is discontinued.
Stanozolol
Stanozolol (Winstrol) is a 17α-alkylated, DHT-derived anabolic steroid first marketed in 1962, now discontinued and Schedule III in the US, WADA-prohibited, and known for cholestatic liver injury and the 1988 Ben Johnson doping case.
Stapedectomy
Stapedectomy is an operation for otosclerosis in which the stapes is removed and replaced with a prosthesis bridging the incus to the inner ear, restoring sound transmission.
Stapedotomy
Stapedotomy is a microsurgical ear procedure that treats hearing loss from otosclerosis by inserting a piston prosthesis through a small opening in the fixed stapes footplate.
Stapes
Stapes: smallest bone of the human body, the third middle-ear ossicle, footplate seated in the oval window; discovered by Ingrassia in 1546 and central to otosclerosis surgery.
Stapes Mobilization
Stapes mobilization is an operation to free the fixed stapes bone of the middle ear, relieving conductive hearing loss from otosclerosis while leaving the stapes in place.
Staphylococcal infection
Staphylococcal infection, mainly Staphylococcus aureus (staph, MRSA/MSSA), disease from skin sores to bacteremia and sepsis; ~30% carriage, biofilm device infections, vancomycin for resistant strains.
Staphylococcal necrotizing pneumonia
Staphylococcal necrotizing pneumonia (SNP): rare, often fatal lung infection from PVL-producing Staphylococcus aureus, typically after influenza, causing hemorrhagic pneumonia, leukopenia, hemoptysis, ARDS, and about 75% mortality.
Staphylococcal scalded skin syndrome
Staphylococcal scalded skin syndrome (SSSS, Ritter's disease) is a blistering skin disorder caused by Staphylococcus aureus exfoliative toxins targeting desmoglein-1, mainly affecting children under 5, with low pediatric but about 60% adult mortality.
Staphylococcal scarlet fever
Staphylococcal scarlet fever, a rare S. aureus toxin-mediated illness mimicking streptococcal scarlet fever: flexural scarlatiniform rash, large-flap desquamation, no strawberry tongue or petechiae, mainly children.
Staphylococcus capitis
Staphylococcus capitis, a coagulase-negative staphylococcus and skin commensal first described in 1975, causes neonatal late-onset sepsis in NICUs; its multidrug-resistant NRCS-A clone, first reported in France in 2012, has spread worldwide.
Staphylococcus saprophyticus
Staphylococcus saprophyticus, a coagulase-negative staphylococcus named by Fairbrother in 1940, is the second most common cause of uncomplicated urinary tract infection in young women after E. coli, peaking in late summer, with foodborne and endogenous reservoirs and nitrofurantoin as first-line therapy.
Staphyloma
Staphyloma: a circumscribed outpouching of the thin cornea or sclera lined by uveal tissue. Posterior staphyloma is a hallmark of pathologic myopia, classified by Curtin into ten types, with no medical treatment.
Staple food
A staple food, or dietary staple, is a food eaten regularly in quantities that make it the dominant part of a population's diet, such as rice, wheat, maize, or potatoes.
Stapled hemorrhoidopexy
Stapled hemorrhoidopexy, also known as the procedure for prolapse and hemorrhoids (PPH), is a surgical procedure that repositions prolapsing internal hemorrhoids with a circular stapler, causing less pain but more recurrence than excisional hemorrhoidectomy.
Stapokibart
Stapokibart (Kangyueda, 康悦达; CM310) is a humanized IgG4 anti-IL-4Rα monoclonal antibody by KeyMed Biosciences, first approved in China in 2024 for moderate-to-severe atopic dermatitis, later CRSwNP and seasonal allergic rhinitis.
Stapuldencel
Stapuldencel (STAPULDENCEL-T, DCVAC/PCa) is SOTIO's autologous dendritic cell prostate cancer vaccine; its phase 3 VIABLE trial (NCT02111577, 1182 patients) showed no overall survival benefit over placebo with docetaxel.