25,729 articles
Suicide prevention
Suicide prevention: public health and clinical efforts to reduce suicide deaths and attempts. Key names: WHO LIVE LIFE, CDC 988. Facts: 720,000+ deaths yearly, means restriction evidence, national strategies.
Sukumara ghrta
Sukumara ghrta (सुकुमारघृत) is an Ayurvedic medicated ghee combining cow ghee and castor oil, listed in the Ayurvedic Formulary of India and used for abdominal and gynecological complaints.
Sulavajrini vatika
Sulavajrini vatika (Śūlavajrīṇī Vaṭikā, Shoolvarjini Vati) is an Ayurvedic herbo-mineral tablet from Rasendrasārasaṅgraha for colic and digestive disorders, containing mercury, sulphur, iron, copper, and Triphala; dose 250-500 mg with warm milk.
Sulbactam-durlobactam
Sulbactam-durlobactam (XACDURO) is a co-packaged IV antibiotic for HABP/VABP from susceptible Acinetobacter baumannii-calcoaceticus complex; FDA-approved May 2023, IDSA-preferred for CRAB with a carbapenem, non-inferior to colistin in ATTACK.
Sulconazole
Sulconazole (Exelderm, Sulcosyn) is a topical imidazole antifungal, 1% cream or solution, FDA-approved 1985, for tinea corporis, cruris, pedis, and versicolor, similar in efficacy to clotrimazole and miconazole.
Sulesomab
Sulesomab (LeukoScan) is a murine Fab' antibody fragment targeting granulocyte NCA-90, labeled with technetium-99m to image suspected osteomyelitis. EU-approved 1997, withdrawn 2018; never FDA-approved.
Sulfabenzamide
Sulfabenzamide (CAS 127-71-9) is a synthetic sulfonamide antibacterial, FDA approved 1945, that inhibits bacterial dihydropteroate synthase. Used mainly in the discontinued triple-sulfa vaginal cream with sulfathiazole and sulfacetamide.
Sulfacarbamide
Sulfacarbamide (sulfanilylurea, Urosulfan), CAS 547-44-4, is a withdrawn sulfonamide anti-infective introduced in the 1940s for bacterial infections; Germany withdrew it in 1992 over a negative benefit/risk ratio.
Sulfacetamide
Sulfacetamide (sodium sulfacetamide, Sodium Sulamyd) is a sulfonamide antibiotic used as a 10% ophthalmic solution for bacterial conjunctivitis and, with sulfur, topically for acne, rosacea, and seborrheic dermatitis.
Sulfacytine
Sulfacytine (Renoquid, CAS 17784-12-2) is a short-acting sulfonamide antibiotic, a PABA analog inhibiting dihydropteroate synthetase, taken orally for urinary tract infections; FDA approved 1975, now discontinued.
Sulfadiazine
Sulfadiazine is a short-acting sulfonamide antibiotic introduced in 1941 that blocks folic acid synthesis in bacteria and is combined with pyrimethamine as standard therapy for toxoplasmosis.
Sulfadicramide
Sulfadicramide (Irgamid, sulfirgamide; INN sulfadicramidum) is a sulfanilamide sulfonamide anti-infective, CAS 115-68-4, C11H14N2O3S, ATC S01AB03, used as a 15% ophthalmic ointment in some countries.
Sulfadoxine/pyrimethamine
Sulfadoxine/pyrimethamine, sold as Fansidar, is a fixed-dose combination of the antimalarials sulfadoxine and pyrimethamine, approved in 1981 and now used mainly to prevent malaria in pregnant women and children.
Sulfaguanidine
Sulfaguanidine (Sulgin, CAS 57-67-0) is a poorly absorbed sulfonamide intestinal antiinfective (ATC A07AB03, DDD 4 g oral) introduced in 1941 for bacillary dysentery, now mostly veterinary, DHPS/PABA-antifolate mechanism.
Sulfalene
Sulfalene (sulfamethopyrazine, Kelfizine) is a long-acting sulfonamide antibiotic (ATC J01ED02, half-life about 65 h) used for respiratory and urinary infections and, with pyrimethamine as Metakelfin, for falciparum malaria, mainly in the Indian subcontinent.
Sulfamerazine
Sulfamerazine is a sulfonamide antibacterial drug, the monomethyl derivative of sulfadiazine, introduced in 1942 and no longer used in human medicine while retaining limited veterinary uses.
Sulfameter
Sulfameter (sulfamethoxydiazine, sulfametoxydiazine, brand Sulla) is a long-acting sulfonamide antibiotic, ATC J01ED04, DDD 0.5 g oral, formerly used for urinary tract infections and leprosy; first approved 1966, now discontinued.
Sulfamethizole
Sulfamethizole (Thiosulfil, Urolucosil) is a short-acting sulfonamide antibiotic, CAS 144-82-1, that inhibits bacterial dihydropteroate synthase and was used mainly for urinary tract infections; no longer marketed in the US.
Sulfamethoxazole
Sulfamethoxazole, a sulfonamide antibiotic (Bactrim with trimethoprim, co-trimoxazole), inhibits DHPS in bacterial folate synthesis; used for Pneumocystis pneumonia, shigellosis, and urinary tract infections.
Sulfamethoxypyridazine
Sulfamethoxypyridazine (Lederkyn, Kynex, Midicel) is a long-acting sulfanilamide sulfonamide antibiotic, N1-(6-methoxy-3-pyridazinyl)sulfanilamide, introduced 1956-1957, half-life 37 h, dihydropteroate synthetase inhibitor, now largely withdrawn.
Sulfanilamide
Sulfanilamide is a synthetic sulfonamide antibacterial drug identified in 1935 as the active agent behind the dye Prontosil, and its 1937 toxic elixir formulation killed over 100 people.
Sulfasalazine
Sulfasalazine, also spelled sulphasalazine and sold as Azulfidine, is a DMARD drug used for rheumatoid arthritis, ulcerative colitis, and Crohn's disease, first synthesized in Sweden in the late 1930s.
Sulfinpyrazone
Sulfinpyrazone (Anturane) is an oral uricosuric drug, a phenylbutazone analog that lowers serum urate in chronic gout by blocking uric acid reabsorption in the kidney.
Sulfisomidine
Sulfisomidine (sulfaisodimidine, Elkosin) is a short-acting sulfonamide antibacterial, CAS 515-64-0, formula C12H14N4O2S, ATC J01EB01, studied for urinary tract infections in the 1950s and now withdrawn.
Sulfisoxazole
Sulfisoxazole is a synthetic sulfonamide antibiotic that stops bacterial growth, available in the United States only combined with erythromycin, prescribed mainly for bacterial ear infections in children.
Sulfonamide (medicine)
Sulfonamide (medicine): sulfa drugs, the oldest synthetic antibacterial class, PABA analogues inhibiting bacterial DHPS; includes sulfamethoxazole, TMP-SMX, sulfadoxine-pyrimethamine; distinguished from non-antibiotic sulfonamides like furosemide and celecoxib, which lack cross-reactivity.
Sulfonylurea
A sulfonylurea, plural sulfonylureas, is an oral antidiabetic drug used in type 2 diabetes that lowers blood glucose by stimulating insulin secretion from pancreatic beta cells.
Sulfoxone
Sulfoxone (aldesulfone, Diasone sodium) is a water-soluble dapsone-derived sulfone formerly used to treat leprosy and dermatitis herpetiformis; it inhibits dihydropteroate synthase and its US product is discontinued.
Suloctidil
Suloctidil (Sulocton, Duolcitil), a peripheral vasodilator and antiplatelet propanolamine drug introduced in 1975 for arterial disease and withdrawn worldwide in the mid-1980s after hepatitis deaths.
Sulodexide
Sulodexide (Vessel, KRX-101) is an orally active glycosaminoglycan drug, 80% fast-moving heparin and 20% dermatan sulfate, used for venous thromboembolism prevention, chronic venous disease, and peripheral arterial disease.