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Human health and medicine

25,729 articles

Tecotabart vedotin

Tecotabart vedotin (LM-302, TPX-4589) is LaNova Medicines' anti-CLDN18.2 antibody-drug conjugate carrying MMAE via a cleavable linker, in priority review in China for CLDN18.2-positive gastric/gastroesophageal junction adenocarcinoma after two prior lines.

Tedisamil

Tedisamil (KC-8857), a class III antiarrhythmic potassium channel blocker developed as a bradycardic agent; intravenous tedisamil converts recent-onset atrial fibrillation to sinus rhythm in about half of patients, with torsade de pointes as the main risk.

TEDIZOAM trial

TEDIZOAM (NCT03378427), Tedizolid Prolonged Treatment for Prosthetic Joint Infections, a prospective cohort study of prolonged tedizolid for orthopedic device infections, assessing tolerability and one-year remission.

Tedizolid

Tedizolid (torezolid, TR-700; prodrug tedizolid phosphate, Sivextro) is a second-generation oxazolidinone antibiotic for ABSSSI, 200 mg once daily for 6 days, more potent than linezolid and active against cfr linezolid-resistant strains.

Teduglutide

Teduglutide (GATTEX, Revestive), a GLP-2 analog peptide, treats short bowel syndrome with parenteral support dependence; approved 2012 (EU/US), pediatric US approval 2019, dose 0.05 mg/kg daily.

Teenage pregnancy

Teenage (adolescent) pregnancy: pregnancy in girls aged 19 or younger. About 21 million pregnancies yearly among girls 15–19 in LMICs; global birth rate fell to 41.3 per 1,000 in 2023; higher maternal and neonatal health risks.

Teething

Teething is the normal eruption of deciduous (baby) teeth through the gums, starting around 4 to 10 months and complete by about 2.5 to 3 years. Evidence links it only to mild local symptoms; fever and diarrhoea suggest other illness. Covers biology, timeline, safe care, and regulation.

Teething syndrome

Teething syndrome (ICD-11 DA07.60) is gum and jaw discomfort when infant teeth emerge, from 4–7 months to about age 3, with irritability, drooling, and swollen gums; fever is not reliably linked.

Tegafur

Tegafur, also known as ftorafur, is an oral fluoropyrimidine prodrug of the anticancer drug 5-fluorouracil, given in combinations such as UFT and S-1 for gastric, colorectal, and breast cancers.

Tegaserod

Tegaserod (Zelnorm), a partial 5-HT4 receptor agonist for IBS-C and chronic constipation; FDA-approved 2002, withdrawn 2007 over cardiovascular ischemic signals, reintroduced 2019 for low-risk women under 65, withdrawn 2022.

Tegileridine fumarate

Tegileridine fumarate (富马酸泰吉利定, SHR8554) is a Jiangsu Hengrui G protein-biased μ-opioid receptor agonist approved in China in January 2024 for moderate-to-severe postoperative pain, analgesia comparable to morphine.

Tegoprazan

Tegoprazan (K-CAB, CJ-12420, 케이캡정) is a potassium-competitive acid blocker from HK inno.N, approved in South Korea in 2018 for GERD, non-inferior to PPIs for erosive esophagitis healing, with US FDA NDA filed January 2026.

Tej Lalvani

Tej Lalvani, British CEO of Vitabiotics (founded 1971 by father Kartar Lalvani) and Dragons' Den investor; firm sold to Bain Capital in 2026 for about $1.2 billion.

Tejal Kanti Gandhi

Tejal Kanti Gandhi is an American physician-executive and patient-safety researcher who leads safety at Press Ganey and was elected to the National Academy of Medicine in 2019.

Tejas Patel

Tejas Madhusudan Patel (born 1963), Indian interventional cardiologist, Chairman of Apex Heart Institute Ahmedabad; transradial PCI pioneer, first-in-man telerobotic coronary intervention 2018; Padma Shri 2015, Padma Bhushan 2024. Distinct from Tejas V. Patel of CIMS.

Tejvir S. Khurana

Tejvir S. Khurana is a Professor of Physiology at the University of Pennsylvania's Perelman School of Medicine whose research on muscular dystrophy earned the Presidential Early Career Award.

Tel Hashomer camptodactyly syndrome

Tel Hashomer camptodactyly syndrome (THCS), or camptodactyly-muscular hypoplasia-skeletal anomalies-abnormal palmar creases syndrome, is an extremely rare, probably autosomal recessive disorder with camptodactyly, muscle hypoplasia, skeletal anomalies, facial dysmorphism, and abnormal dermatoglyphics.

Telangiectasia

Telangiectasia (telangiectases, broken capillaries) is the permanent dilation of small superficial blood vessels visible as fine red lines on skin or mucous membranes; causes include rosacea, sun damage, pregnancy, and HHT, treated by sclerotherapy or vascular lasers.

Telavancin

Telavancin (Vibativ, TD-6424) is a semisynthetic lipoglycopeptide antibiotic derived from vancomycin, FDA-approved in 2009 for complicated skin infections and 2013 for pneumonia, with dual cell wall and membrane action and nephrotoxicity risk.

Telazorlimab

Telazorlimab (GBR 830, ISB 830) is a humanized anti-OX40 IgG1 monoclonal antibody for atopic dermatitis; completed phase 2b (EASI −54.4% vs −34.2% placebo), licensed to Astria Therapeutics 2023, now under BioCryst after its 2026 Astria acquisition.

Telcagepant

Telcagepant (MK-0974) was Merck's first oral CGRP receptor antagonist (gepant) for acute migraine, with efficacy comparable to zolmitriptan but no vasoconstriction; development was discontinued in 2011 over hepatotoxicity in daily-dosing prophylaxis trials.

Telecanthus

Telecanthus, also called dystopia canthorum or pseudohypertelorism, is an increased distance between the inner eyelid corners (medial canthi) with normal pupil spacing, usually from genetic syndromes or facial trauma, treated surgically.

Teledermoscopy

Teledermoscopy is a telemedicine method in dermatology in which dermoscopic images of skin lesions are transmitted to a remote specialist for consultation and triage of suspected skin cancer.

Telehealth

Telehealth, also called telemedicine, is the delivery of health care services at a distance through telecommunications technology, including video visits, remote monitoring, diagnosis, and health education.

Telemonitoring

Telemonitoring is the remote monitoring of a patient's condition using connected medical devices and sensors, with data transmitted to health workers, often for chronic conditions.

Telenurse-CKD trial

The Telenurse-CKD trial is a randomized controlled trial at Istanbul University-Cerrahpasa testing nurse-led tele-nursing in 66 adults with stage 3-4 chronic kidney disease not yet on dialysis.

Telerehabilitation

Telerehabilitation (remote rehabilitation, teletherapy, virtual rehabilitation): delivery of rehabilitation services over a distance via ICT; synchronous, asynchronous, or hybrid; WFNR 2025 consensus definition; evidence of equivalence with in-person care.

Teletherapy (radiation therapy)

Teletherapy, also called external-beam radiation therapy, treats cancer by directing ionizing radiation from a source outside the body at a defined target volume, one of radiotherapy's two main forms alongside brachytherapy.

Telethonin-related limb-girdle muscular dystrophy R7

Telethonin-related limb-girdle muscular dystrophy R7 (LGMDR7), formerly LGMD2G, is a rare autosomal recessive muscular dystrophy caused by TCAP gene variants that eliminate telethonin, causing progressive limb weakness with onset from infancy to adulthood.

Teleworking

Teleworking (telework, telecommuting): performing work outside the employer's premises using ICT, since the 1970s and mass-scale since COVID-19; hybrid and fully remote forms, small positive productivity effect, ergonomic and musculoskeletal risks.