edgepedia

Human health and medicine

25,729 articles

The Man Who Mistook His Wife for a Hat

The Man Who Mistook His Wife for a Hat, Oliver Sacks's 1985 book of neurological case histories including Dr. P.'s visual agnosia; million-selling best-seller adapted into a Michael Nyman opera and credited with reviving narrative medicine.

The Maria Sklodowska-Curie National Research Institute of Oncology

Maria Skłodowska-Curie National Research Institute of Oncology (NIO-PIB, Narodowy Instytut Onkologii), Poland's largest cancer center, successor of the 1932 Warsaw Radium Institute; four sites, 500+ clinical trials, first Polish OECI-accredited oncology center.

The Medical journal

The Medical Journal (ISSN 2694-3581 print, 2694-3611 electronic) is the quarterly, peer-reviewed periodical of the US Army Medical Center of Excellence, published by the Borden Institute, Fort Sam Houston, since 2020, continuing the U.S. Army Medical Department journal and indexed in MEDLINE.

The New England Journal of Medicine

The New England Journal of Medicine (NEJM) is a weekly peer-reviewed general medical journal founded in Boston in 1812, published by the Massachusetts Medical Society, with a 2025 impact factor of 84.5 and an archive back to 1812.

The OAT-RCT trial

OAT-RCT (Obesity Anti-Coagulation Thromboprophylaxis Trial, NCT07559643): single-center Dublin RCT comparing weight-based tinzaparin vs weight-stratified enoxaparin for 21-day VTE prophylaxis after laparoscopic bariatric surgery; primary endpoint anti-Xa 0.2–0.4 IU/mL; 180 participants, starting August 2026.

The oncologist

The Oncologist (ISSN 1083-7159 print, 1549-490X online) is a monthly peer-reviewed oncology and hematology journal founded in 1996 by AlphaMed Press, later published by Wiley and, since January 2022, by Oxford University Press as a fully open access online-only journal edited by Susan E. Bates.

The Real Anthony Fauci

The Real Anthony Fauci (2021), Robert F. Kennedy Jr.'s 480-page bestseller accusing Fauci, Bill Gates, and pharma of a 'vaccine cartel' and COVID cover-up; key claims debunked by fact-checkers.

The Royal Free Hospital

The Royal Free Hospital, founded by William Marsden in 1828 as London's first free hospital, moved from Gray's Inn Road to Pond Street, Hampstead in 1974; now part of Royal Free London NHS Foundation Trust.

The Three Christs of Ypsilanti

The Three Christs of Ypsilanti is Milton Rokeach's 1964 psychiatric case study of his two-year experiment at Ypsilanti State Hospital, Michigan, where three paranoid schizophrenic patients, Clyde Benson, Joseph Cassel, and Leon Gabor, each claiming to be Jesus Christ, were confronted with one another; none was cured, and Rokeach later apologized for the ethics.

The University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center, founded 1941 in Houston's Texas Medical Center, is a top-ranked NCI comprehensive cancer hospital; U.S. News has ranked it No. 1 in U.S. cancer care for 12 consecutive years.

Theca lutein cyst

Theca lutein cyst (hyperreactio luteinalis): bilateral multiseptated functional ovarian cysts caused by high hCG, seen in molar pregnancy, multiple gestation, and ovarian hyperstimulation; regress as hCG falls.

Thecal sac

Thecal sac (dural sac, saccus durae matris spinalis): the dural sheath in the spinal canal enclosing the spinal cord, cauda equina, and cerebrospinal fluid; key MRI stenosis marker, lumbar puncture target, and SBRT contour.

Thelarche

Thelarche is the onset of breast development in girls, the first clinical sign of puberty (Tanner B2), typically at 9-10 years, declining about 3 months per decade since 1977.

Themistocles Gluck

Themistocles Gluck (1853–1942) was a German surgeon who performed the first total joint replacements in Berlin in 1890, using hinged ivory prostheses fixed with an early bone cement.

Thenalidine

Thenalidine (thenophenopiperidine, AS 716, Sandostene) is a withdrawn piperidine H1-antihistamine introduced in 1953 for allergic and dermatologic conditions; severe neutropenia cases led to US withdrawal in 1958 and later withdrawals elsewhere.

Thenar eminence

Thenar eminence: the fleshy muscle mound at the base of the thumb, formed by abductor pollicis brevis, flexor pollicis brevis, and opponens pollicis, mainly median-nerve innervated; atrophy signals carpal tunnel syndrome.

Theodor Morell

Theodor Morell (1886–1948), German urologist and Hitler's personal physician from 1936/37 to April 1945; gave over 1,000 injections and 92 medications, built a pharma empire, and died unprosecuted at Tegernsee.

Theodore Cooper

Theodore Cooper (1928–1993) was an American physician and federal health official who directed the National Heart and Lung Institute and shaped the 1976 Medical Device Amendments.

Theodore Corbin

Theodore Corbin is an American emergency medicine physician who chairs emergency medicine at RUSH University Medical Center and designed the Healing Hurt People violence-recovery program.

Theodore G. Ganiats

Theodore G. Ganiats is an American family physician and outcomes researcher, professor emeritus of family medicine at UC San Diego, known for quality-of-life assessment and cost-effectiveness analysis.

Theophylline

Theophylline (1,3-dimethylxanthine), a methylxanthine bronchodilator related to caffeine, treats asthma and COPD; narrow 5-20 mcg/mL therapeutic window, PDE inhibition and HDAC-mediated anti-inflammatory action, now alternative therapy.

Theranostic Nanomedicine

Theranostic nanomedicine, or nanotheranostics, integrates diagnostic imaging and targeted therapy in a single nanoparticle platform. Key examples include NBTXR3 hafnium oxide radioenhancers, NanoTherm iron oxide glioma therapy, and ferumoxytol MRI agents; translation is limited by heterogeneity, manufacturing, and regulation.

Theranostics

Theranostics, a term coined in 1998 fusing therapy and diagnostics, is the nuclear medicine practice of imaging a tumor target and treating it with a matched radiopharmaceutical.

Therapeutic abortion

Therapeutic abortion is the intentional termination of a pregnancy that endangers the woman's health or life, or in which the fetus has a condition incompatible with normal life.

Therapeutic angiogenesis

Therapeutic angiogenesis is a regenerative-medicine treatment that stimulates new blood vessel growth in ischemic tissue, mainly for critical limb ischemia and refractory angina when bypass or angioplasty is not possible.

Therapeutic apheresis

Therapeutic apheresis is a medical procedure that removes specific blood components, such as plasma, cells, or lipids, from a patient's circulation to treat disease. Its defining procedure is therapeutic plasma exchange.

Therapeutic delivery

Therapeutic Delivery is a MEDLINE-indexed peer-reviewed academic journal covering drug delivery, founded by Future Science in 2010 and published by Taylor & Francis since 2024, printing original research and reviews.

Therapeutic drug monitoring

Therapeutic drug monitoring (TDM) is the measurement of drug concentrations in blood, with pharmacological interpretation, to individualize and adjust dosing for drugs with narrow therapeutic windows.

Therapeutic horseback riding

Therapeutic horseback riding (THR) is an equine-assisted service in which individuals ride horses under trained supervision to improve physical, psychological, and social functioning, recognizable since the mid-twentieth century.

Therapeutic index

Drug therapeutic index (TI, therapeutic ratio): ratio of toxic dose (TD50 or LD50) to effective dose (ED50); values above 10 indicate a wide safety margin, while narrow-TI drugs like warfarin and digoxin require therapeutic drug monitoring.