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Tetany
Tetany: involuntary muscle contractions from overstimulated peripheral nerves, usually due to low ionized calcium (hypocalcemia) or alkalosis. Features carpopedal spasm, Chvostek and Trousseau signs, laryngospasm; treated with IV calcium gluconate.
Tetatox
Tetatox is an adsorbed tetanus toxoid vaccine (ATC J07AM01, 40 IU/0.5 ml) made by BB-NCIPD EAD, Bulgaria, WHO-prequalified since 2006 (FVP-P-76) and registered in Hungary, Malta, Ukraine, Greece, and other countries.
Tethered capsule endomicroscopy
Tethered capsule endomicroscopy (TCE) is a sedation-free imaging method in which a swallowed, tethered capsule captures microscopic images of the esophageal lining, used to screen for Barrett's esophagus.
Tethered cord syndrome
Tethered cord syndrome (TCS), abnormal fixation of the spinal cord causing traction, pain, and bladder or motor deficits; first described by Hoffman et al. 1976; treated by detethering or spinal column shortening.
Tetomilast
Tetomilast (OPC-6535) is an investigational oral PDE4 inhibitor developed by Otsuka Pharmaceutical for ulcerative colitis, Crohn's disease, and COPD; its phase II and III trials missed primary endpoints and development was discontinued or stalled.
Tetraamelia-multiple malformations syndrome
Tetraamelia-multiple malformations syndrome (Zimmer phocomelia, PAPPA syndrome, ORPHA:3301) is an extremely rare, mostly lethal autosomal recessive disorder with absence of all four limbs plus head, lung, cardiac, and urogenital malformations; WNT3 and RSPO2 are known causes.
Tetrachromacy
Tetrachromacy is possession of four independent color channels, usually four cone types from X-linked opsin heterozygosity in women; strong functional tetrachromacy is rare, weak forms more common, and no online tests are valid.
Tetracycline
Tetracycline, a broad-spectrum antibiotic of the tetracycline class (chlortetracycline, Aureomycin, doxycycline), made in 1953 from chlortetracycline; bacteriostatic 30S ribosome inhibitor limited by efflux and ribosomal-protection resistance and tooth staining in children.
Tetradecyl sulfuric acid
Tetradecyl sulfuric acid, as sodium tetradecyl sulfate (STS, Sotradecol), is a detergent sclerosant introduced by Leopold Reiner in 1946, FDA approved for varicose veins, used in liquid or foam sclerotherapy and compared with polidocanol.
Tetragametic chimerism syndrome
Tetragametic chimerism syndrome (46,XX/46,XY chimerism, ORPHA:199310, ICD-11 LD56) is a rare disorder of sex development from fusion of two zygotes, causing ambiguous genitalia, infertility, and dual DNA profiles.
Tetrahydrocannabinol
Tetrahydrocannabinol (THC, delta-9-THC, dronabinol), the principal psychoactive cannabinoid of Cannabis sativa, isolated by Mechoulam and Gaoni in 1964; partial CB1 agonist, FDA-approved as dronabinol and nabilone, potency rising to 16.14%.
Tetralogy of Fallot
Tetralogy of Fallot is a congenital heart defect combining four abnormalities that cause low blood oxygen and bluish skin; surgical repair in infancy gives over 90% survival to adulthood.
Tetralogy of Fallot repair
Tetralogy of Fallot repair is an open-heart operation that corrects the congenital defect by closing the ventricular septal defect and relieving right ventricular outflow obstruction, routinely performed in infancy since the 1950s.
Tetraplegia
Tetraplegia (quadriplegia) is paralysis of all four limbs from cervical spinal cord injury, C1–T1, affecting arm and leg function, breathing, and daily living; distinguished from paraplegia by affected arm function.
Tetrasomy 18p syndrome
Tetrasomy 18p syndrome, also called isochromosome 18p, is a very rare chromosomal disorder with four copies of chromosome 18p, causing developmental delay, hypotonia, microcephaly, and dysmorphic features; OMIM 614290.
Tetrasomy 21 syndrome
Tetrasomy 21 syndrome, also called isochromosome 21, is an extremely rare chromosomal disorder with four copies of chromosome 21, causing Down syndrome-like features, hypotonia, intellectual disability, and early hematologic malignancy risk.
Tetrasomy 5p syndrome
Tetrasomy 5p syndrome, also known as isochromosome 5p, is a rare chromosomal disorder in which cells carry four copies of chromosome 5's short arm, causing developmental delay, hypotonia, and seizures.
Tetrasomy 9p syndrome
Tetrasomy 9p syndrome is a rare chromosomal disorder with four copies of chromosome 9's short arm, first described in 1973, causing developmental delay and birth defects.
Tetrazepam
Tetrazepam, marketed as Myolastan, is a benzodiazepine muscle relaxant for painful muscle contractures and spasticity, withdrawn across the European Union in 2013 after a safety review.
Tetrazine–trans-cyclooctene pretargeting
Tetrazine–trans-cyclooctene pretargeting is a two-injection strategy for PET imaging and radioimmunotherapy in which a TCO-modified antibody is detected with a radiolabeled tetrazine via IEDDA ligation.
Tetrofosmin
Tetrofosmin (Myoview) is a lipophilic cationic diphosphine chelating technetium-99m, a SPECT radiopharmaceutical for myocardial perfusion and left ventricular function imaging, FDA approved 1996, distinguished from sestamibi by faster liver clearance.
Tetryzoline
Tetryzoline (tetrahydrozoline), an imidazoline alpha-1 adrenergic agonist decongestant since 1959, used in Visine eye drops (0.05%) and Tyzine nasal spray; toxic if ingested, especially by children.
Teva Pharmaceuticals
Teva Pharmaceutical Industries Ltd. (טבע, "nature") is an Israeli multinational pharmaceutical company founded in Jerusalem in 1901, a world generics leader (3,500 products, 200 million daily users) pivoting toward innovative brands AUSTEDO, AJOVY, and UZEDY under its Pivot to Growth strategy.
Texas Children's Hospital
Texas Children's Hospital: not-for-profit pediatric hospital in Houston, founded 1954, Baylor College of Medicine teaching site, largest freestanding pediatric hospital in the US, top-ranked by U.S. News.
Texas Heart Institute
The Texas Heart Institute is a nonprofit cardiovascular research, education, and patient-care center in Houston's Texas Medical Center, founded by heart surgeon Denton A. Cooley in 1962.
Texas Medical Center
The Texas Medical Center (TMC) in Houston is the world's largest medical complex: 1,345 acres, 61 member institutions including MD Anderson and Baylor College of Medicine, founded 1945 under Ernst Bertner, with 120,000 employees and 10 million patient visits yearly.
Texas Tech University Health Sciences Center
Texas Tech University Health Sciences Center (TTUHSC), founded 1969 as Texas Tech's School of Medicine and renamed 1979, is a separate multi-campus public health sciences university in West Texas with six schools, flagship in Lubbock, Carnegie R2 research designation.
Textile and clothing contact dermatitis
Textile and clothing contact dermatitis is eczema caused by clothing, footwear, or household textiles, usually from allergy to disperse dyes and formaldehyde resins rather than the fibers.
Tezacaftor
Tezacaftor (VX-661) is a Vertex CFTR corrector for cystic fibrosis, given with ivacaftor as Symdeko and in triple regimens Trikafta and Alyftrek; FEV1 +4.0 points, exacerbations down 35%.
Tezacaftor/ivacaftor therapy
Tezacaftor/ivacaftor, sold as Symdeko in the US and Symkevi in Europe, is an oral combination therapy for cystic fibrosis, pairing a CFTR corrector with a potentiator, approved in 2018.