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Terahertz imaging
Terahertz imaging is a medical imaging technique that uses 0.1–5 THz radiation, strongly absorbed by water, to distinguish diseased from healthy tissue, chiefly in skin cancer.
Teratogenesis
Teratogenesis: production of birth defects by teratogens such as thalidomide, alcohol, rubella, and valproic acid; risk depends on dose, timing, and genetics, peaking at 3–8 weeks gestation.
Teratoma
A teratoma, also called a dysembryoma, is a germ cell tumor that can contain hair, muscle, and bone, most often found in the ovaries, testicles, or tailbone.
Terbinafine
Terbinafine (Lamisil) is an allylamine antifungal, discovered 1983 at Sandoz, that inhibits fungal squalene epoxidase; oral 250 mg tablets treat onychomycosis, topical 1% cream treats skin dermatophyte infections.
Terbutaline
Terbutaline (Bricanyl, Brethine) is a short-acting beta-2 agonist bronchodilator approved by the FDA in 1974 for bronchospasm in asthma, bronchitis, and emphysema; contraindicated for tocolysis.
Terconazole
Terconazole (Terazol, Zazole) is a prescription triazole antifungal vaginal cream and suppository for vulvovaginal candidiasis in adult females; U.S. approved 1987, inhibiting fungal lanosterol demethylase.
Teres major muscle
Teres major muscle (musculus teres major): thick shoulder muscle from the inferior scapula to the humerus; extends, internally rotates, and adducts the arm; innervated by the lower subscapular nerve; not a rotator cuff muscle; used in tendon transfers.
Teres minor muscle
Teres minor muscle (Musculus teres minor), one of the four rotator cuff muscles, runs from the scapula's lateral border to the humerus's greater tubercle; axillary nerve (C5-C6) innervates it for external rotation, adduction, and shoulder stabilization.
Terevalefim
Terevalefim (ANG-3777, Refanalin, SNV-003) is an investigational small-molecule HGF mimetic and c-Met agonist from Angion Biomedica, in phase 3 trials for delayed graft function; COVID-19 and cardiac-surgery AKI trials missed endpoints.
Teriflunomide
Teriflunomide (Aubagio) is an oral once-daily disease-modifying therapy for relapsing forms of multiple sclerosis, US-approved September 12, 2012. A reversible dihydroorotate dehydrogenase inhibitor and leflunomide metabolite, with hepatotoxicity and embryofetal toxicity boxed warnings.
Teriparatide
Teriparatide (Forteo, Forsteo), recombinant human PTH(1-34), is the first anabolic osteoporosis drug, FDA-approved 2002; 20 mcg daily subcutaneous injection, 2-year lifetime limit, rat osteosarcoma warning.
Terlipressin
Terlipressin, sold as Glypressin and as Terlivaz in the United States, is a synthetic vasopressin analog drug used mainly for type 1 hepatorenal syndrome in cirrhosis and for bleeding esophageal varices.
Terminal illness
A terminal illness, also called a terminal or end-stage disease, is a disease that cannot be cured or controlled with treatment and is expected to lead to death.
Terminal lucidity
Terminal lucidity, also called paradoxical lucidity or "the surge," is the unexpected return of mental clarity and memory shortly before death in people with severe dementia, schizophrenia, or other neurologic and psychiatric disorders; cause unknown, episodes last seconds to hours.
Terminal myelocystocele
Terminal myelocystocele (TMCC) is a rare occult spinal dysraphism in which the terminal spinal cord herniates with a trumpet-shaped CSF cyst through spina bifida, arising from secondary neurulation arrest and often linked to cloacal exstrophy and OEIS complex.
Terminology of transgender anatomy
Terminology of transgender anatomy: the clinical and educational vocabulary for describing transgender and nonbinary people's bodies, including organ inventories, preferred anatomical language, post-surgical anatomy terms, and outdated terms like FtM/MtF.
Terodiline
Terodiline (TD 758, Bicor) is a withdrawn antimuscarinic and calcium antagonist once used for urinary frequency and incontinence; marketed from 1986, withdrawn in 1991 for QT prolongation and torsades de pointes caused by its R(+) enantiomer.
Terrien marginal degeneration
Terrien marginal degeneration (TMD), also called Terrien's marginal degeneration, is a rare, slowly progressive, usually non-inflammatory thinning of the peripheral cornea causing high against-the-rule astigmatism, lipid deposition, vascularization, and rare perforation.
Terry Dubrow
Terry Dubrow, American board-certified plastic surgeon in Beverly Hills, star of E!'s Botched with Paul Nassif, former surgeon on Fox's The Swan (2004), husband of RHOC's Heather Dubrow.
Terry L. Vanden Hoek
Terry L. Vanden Hoek is an American emergency physician who heads Emergency Medicine at the University of Illinois Chicago and was elected to the National Academy of Medicine in 2023.
Terry Paul Klassen
Terry Paul Klassen is a Canadian pediatric emergency physician and clinical trials methodologist who co-founded PERC and PERN and led the Children's Hospital Research Institute of Manitoba.
TERT promoter mutation analysis
TERT promoter mutation analysis is a molecular pathology test detecting C228T and C250T mutations to diagnose and stratify cancers, especially gliomas, bladder cancers, and melanomas.
Tertatolol
Tertatolol (S 2395, Artex) is a Servier-developed nonselective beta-blocker without intrinsic sympathomimetic activity, ATC C07AA16, dosed 5 mg once daily for hypertension, with renal vasodilating and 5-HT1A antagonist properties; French marketing ended 2023.
Tertiary Care Centers
Tertiary care centers, also called tertiary or referral hospitals, are hospitals providing subspecialty expertise for patients referred from secondary care; key facts include MeSH definition, care pyramid position, quaternary extension, and global access figures.
Tertiary Health Care
Tertiary health care is the third tier of a health system: highly specialized consultative and hospital services such as organ transplantation and intensive care, provided at referral and teaching hospitals, usually on referral from primary and secondary care.
Tertiary Prevention
Tertiary prevention, the third prevention level after primary and secondary, applies supportive and rehabilitative services after disease is established to minimize morbidity, prevent complications, and maximize quality of life.
Tertiary yaws
Tertiary yaws, the late stage of yaws (framboesia, pian) caused by Treponema pallidum subspecies pertenue, appears 5-10 years after untreated infection in about 10% of patients, causing noninfectious destructive gummatous lesions of skin, bone, and cartilage (gangosa, goundou, saber shin), now rarely seen.
Tertomotide
Tertomotide (GV1001, Riavax) is a 16-amino-acid telomerase (hTERT 611-626) peptide cancer vaccine from GemVax & KAEL; immunogenic in pancreatic, lung cancer and melanoma trials, but it failed to improve survival in the TeloVac phase III pancreatic trial and is now studied for Alzheimer's disease.
Terutroban
Terutroban (S 18886, Triplion) is Servier's oral, reversible thromboxane-prostaglandin (TP) receptor antagonist antiplatelet drug; development stopped after the 19,120-patient PERFORM trial failed noninferiority versus aspirin.
Tesaglitazar
Tesaglitazar (Galida, AZ-242), an AstraZeneca dual PPARα/γ agonist for type 2 diabetes, lowered glucose and triglycerides in trials but was discontinued in May 2006 over creatinine and GFR effects.