25,729 articles
Tezepelumab
Tezepelumab (Tezspire, tezepelumab-ekko) is a human IgG2λ monoclonal antibody blocking TSLP, FDA-approved 2021 as add-on therapy for severe asthma age 12+, dosed 210 mg subcutaneously every 4 weeks, cutting exacerbations about 44-60% in NAVIGATOR and PATHWAY.
Tezosentan
Tezosentan (Ro 61-0612) is an intravenous, short-acting dual endothelin ETA/ETB receptor antagonist developed by Actelion as a vasodilator for acute heart failure; RITZ and VERITAS trials showed hemodynamic effects but no clinical benefit, and development was discontinued.
TF-1
TF-1 (TF1, MFD-1) is a human erythroleukemia cell line established in 1987 from a 35-year-old Japanese man with AML M6, dependent on GM-CSF or IL-3 for growth, with a truncated translocated EPO receptor and factor-independent derivatives such as TF-1a.
TFC-SEPSIS study
TFC-SEPSIS (NCT06572995) is a French observational study by CHRU Brest evaluating thoracic fluid content measured by bio-reactance against bedside fluid-overload indices in 50 adults with Sepsis-3 septic shock, started June 2023.
TFR2-related hemochromatosis
TFR2-related hemochromatosis (hemochromatosis type 3, HFE3, OMIM 604250) is a rare autosomal recessive iron-overload disease from TFR2 gene mutations on chromosome 7, causing low hepcidin, iron accumulation, and an intermediate phenotype treated by phlebotomy.
tFUS trial
A tFUS trial is a clinical study of transcranial focused ultrasound, which delivers low-intensity ultrasound pulses through the skull to stimulate the thalamus in disorders of consciousness.
TG103
TG103 (依达格鲁肽α) is a once-weekly GLP-1/Fc fusion protein injection by CSPC Baike for type 2 diabetes and obesity; phase 3 trials completed in China, CDE filing accepted.
Thalamotomy
Thalamotomy: neurosurgical ablation of the thalamic ventral intermediate (Vim) nucleus to treat medication-refractory tremor in essential tremor and tremor-dominant Parkinson's disease, performed by radiofrequency, radiosurgery, or MR-guided focused ultrasound.
Thalamus
Thalamus: paired ovoid gray-matter nuclei at the top of the brainstem relaying all sensory information except smell to cortex; also gates consciousness, sleep rhythms, cognition, and is a target for DBS in tremor and epilepsy.
Thalassaemias
Thalassaemias (also thalassemias): inherited alpha- and beta-globin disorders causing anaemia, first described 1925, commonest monogenic diseases; treated with transfusion, chelation, HSCT, and approved gene therapies Casgevy and Zynteglo.
Thalassemia
Thalassemia, an inherited autosomal recessive blood disorder of alpha- or beta-globin genes causing anemia; treated with transfusions, chelation, stem cell transplant, gene therapy (Zynteglo, Casgevy), and mitapivat.
Thalassophobia
Thalassophobia, also called fear of the ocean or deep water, is a specific phobia of vast, deep, dark bodies of water, distinct from aquaphobia (fear of water itself); treated mainly with exposure therapy and CBT.
Thalidomide embryopathy
Thalidomide embryopathy: congenital anomalies from in utero thalidomide exposure days 20-36 after fertilization; over 10,000 affected children 1957-1962; limb, ear, eye, heart defects; still seen in Brazil.
Thallium poisoning
Thallium poisoning, illness from the tasteless, odorless heavy metal Tl that mimics potassium; causes gastroenteritis, painful neuropathy, and alopecia; treated with Prussian blue, FDA-approved 2003.
Thanatophoric dysplasia
Thanatophoric dysplasia (TD), also called FGFR3-related thanatophoric dysplasia, is a lethal short-limb skeletal dysplasia caused by gain-of-function FGFR3 variants; types 1 and 2 differ by bowed versus straight femurs and cloverleaf skull.
THAPCA-OH trial
THAPCA-OH (NCT00878644), Therapeutic Hypothermia after Pediatric Cardiac Arrest Out-of-Hospital, a NHLBI-funded RCT in comatose children after out-of-hospital cardiac arrest; hypothermia 33.0°C vs normothermia 36.8°C showed no significant benefit (20% vs 12% favorable outcome).
The American journal of surgical pathology
The American Journal of Surgical Pathology (AJSP, ISSN 0147-5185) is a monthly peer-reviewed surgical pathology journal founded in 1977, edited by Stacey E. Mills, published by Wolters Kluwer/LWW, 2025 impact factor 4.2.
The annals of otology, rhinology, and laryngology
The Annals of Otology, Rhinology, and Laryngology (Ann Otol Rhinol Laryngol) is a monthly peer-reviewed US otolaryngology journal founded in 1897 in St. Louis by James Pleasant Parker, published by Sage since 2014, ISSN 0003-4894.
The Behavioral and brain sciences
Behavioral and Brain Sciences (BBS), Cambridge University Press journal founded 1978 by Stevan Harnad, known for Open Peer Commentary: target articles co-published with 20–40 invited cross-disciplinary commentaries and the author's response.
The Brain Prize
The Brain Prize is an annual award of DKK 10 million, about €1.3 million, given by Denmark's Lundbeck Foundation since 2011 to brain researchers of any nationality.
The China Study
The China Study is a 2005 book by T. Colin and Thomas Campbell advocating whole-food plant-based diets, based on the China–Cornell–Oxford Project survey of 65 rural Chinese counties and rat casein experiments; its causal claims drew major statistical criticism.
The Diving Bell and the Butterfly
The Diving Bell and the Butterfly (Le Scaphandre et le Papillon), Jean-Dominique Bauby's 1997 memoir dictated by blinking his left eye with locked-in syndrome, and Julian Schnabel's 2007 Cannes Best Director film adaptation.
The First Affiliated Hospital, Sun Yat-sen University
The First Affiliated Hospital, Sun Yat-sen University (中山大学附属第一医院), founded 1910 in Guangzhou, is a top-tier tertiary Grade A teaching hospital with 36 national clinical key specialties, A++ performance ratings, and campuses in Yuexiu, Huangpu, and Nansha.
The Jerry Lewis MDA Labor Day Telethon
The Jerry Lewis MDA Labor Day Telethon, also called the MDA Show of Strength in later years, was Jerry Lewis's annual Muscular Dystrophy Association charity broadcast, held Labor Day weekends 1966 to 2014, raising over $1 billion and ending in 2015.
The Journal of clinical psychiatry
The Journal of Clinical Psychiatry (JCP), ISSNs 0160-6689 print and 1555-2101 online, is a peer-reviewed psychiatry journal founded 1939, published by Physicians Postgraduate Press, Memphis, and official journal of the American Society of Clinical Psychopharmacology since 2005.
The Journal of Heart and Lung Transplantation
The Journal of Heart and Lung Transplantation (J Heart Lung Transplant), Elsevier-published monthly journal of the International Society for Heart and Lung Transplantation since 1991; 2025 impact factor 6.7, formerly ranked first among transplantation journals.
The Journal of the American Dental Association
The Journal of the American Dental Association (JADA), ISSN 0002-8177, is the American Dental Association's monthly peer-reviewed flagship journal, published since 1913, now with Elsevier, known for ADA clinical practice guidelines and a 2025 impact factor of 4.4.
The Lancet
The Lancet: weekly peer-reviewed general medical journal founded 5 October 1823 in London by Thomas Wakley, now published by Elsevier; 2024 impact factor 109.0, editor-in-chief Richard Horton, known for campaigning editorials and the 2020 Surgisphere retraction.
The Lancet. Neurology
The Lancet. Neurology (Lancet Neurol), monthly Elsevier neurology journal launched May 2002, ISSN 1474-4422; edited by Elena Becker-Barroso since 2012; 2025 impact factor 54.6, ranked first among clinical neurology journals.
The Laryngoscope
The Laryngoscope is a monthly peer-reviewed otolaryngology journal founded in 1896 in St. Louis by Max Goldstein and Frank Rumbold, owned by the Triological Society, published by Wiley, and edited by Samuel H. Selesnick.