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Bence Jones proteinuria
Bence Jones proteinuria, also called Bence Jones protein or urinary monoclonal free light chains, is the excretion of monoclonal kappa or lambda immunoglobulin light chains in urine, classically in multiple myeloma, detected by urine immunofixation and distinguished from albuminuria by its heat solubility and dipstick negativity.
Bencycloquidium bromide nasal spray
Bencycloquidium bromide nasal spray (苯环喹溴铵鼻喷雾剂, brand Biliting) is Yingu Pharmaceutical's class 1 Chinese new drug, a selective M1/M3 anticholinergic spray approved in March 2020 for allergic rhinitis nasal symptoms, with a 2025 common-cold indication added.
Bendamustine
Bendamustine (Treanda, Ribomustin, Cytostasan) is a bifunctional nitrogen mustard alkylating agent synthesized in 1963 in East Germany, FDA-approved in 2008 for CLL and rituximab-refractory indolent B-cell NHL, improving progression-free but not overall survival.
Bendamustine and rituximab regimen
The bendamustine and rituximab (BR) regimen is a chemoimmunotherapy combination pairing the alkylating drug bendamustine with the antibody rituximab, given in up to six 28-day cycles for B-cell malignancies including indolent lymphoma and CLL.
Bendazac
Bendazac (bendazac lysine, bendazolic acid) is an indazole NSAID whose main action is inhibiting protein denaturation; its lysine salt was used as eyedrops and 500 mg oral tablets to delay cataract, and it was withdrawn in several regions over hepatotoxicity concerns.
Benfluorex
Benfluorex (Mediator), a fenfluramine-derivative appetite suppressant and antidiabetic add-on drug marketed by Servier from 1976, withdrawn in France in 2009 and the EU in 2010 for causing 5-HT2B-mediated valvular heart disease.
Benfotiamine
Benfotiamine (S-benzoylthiamine O-monophosphate), a lipid-soluble synthetic thiamine (vitamin B1) derivative with higher bioavailability, activating transketolase; used for diabetic peripheral neuropathy in some countries and in trials for early Alzheimer's disease.
Benidipine
Benidipine (Coniel) is a Japanese dihydropyridine calcium channel blocker, launched in 1991 by Kyowa Hakko, that blocks L-, N-, and T-type calcium channels and treats hypertension and angina; trials show kidney benefits over amlodipine in CKD.
Benign acanthosis nigricans
Benign acanthosis nigricans is a skin condition with dark, thick, velvety patches in body folds such as the neck and armpits, caused by insulin resistance and obesity rather than cancer.
Benign breast disease
Benign breast disease (benign breast conditions): noncancerous breast changes including cysts, fibroadenomas, fibrocystic changes, mastalgia, and mastitis; risk of later breast cancer depends on histology, from no elevation for nonproliferative lesions to roughly four-fold for atypical hyperplasia.
Benign cephalic histiocytosis
Benign cephalic histiocytosis (BCH), a rare self-healing non-Langerhans cell histiocytosis of infants, causing yellowish-red papules on the head and neck; CD68-positive, CD1a-negative, Birbeck granules absent, ICD-10 D76.3.
Benign endometrial stromal nodule
Benign endometrial stromal nodule (ESN), also called benign endometrial stromal neoplasm, is a non-infiltrating benign uterine mesenchymal tumor resembling proliferative-phase endometrial stroma, defined by pushing margins, absent lymphovascular invasion, CD10 positivity, and JAZF1-SUZ12 fusions.
Benign fasciculation syndrome
Benign fasciculation syndrome (BFS): frequent harmless muscle twitching at rest without underlying disease, diagnosed by normal exam, EMG, and exclusion; long-term studies show no progression to ALS.
Benign fibrohistiocytic tumour
Benign fibrohistiocytic tumour (ICD-11 2E85) is a WHO category of benign mesenchymal neoplasms with cells resembling fibroblasts and histiocytes; prototype dermatofibroma (fibrous histiocytoma), a common benign skin nodule of the limbs.
Benign focal seizures of adolescence
Benign focal seizures of adolescence (BFSA, adolescent benign focal crisis): rare idiopathic seizure-susceptibility condition peaking at 13-15 years, with one or 2-5 focal seizures within 36 hours, normal EEG and MRI, no recurrence, no treatment needed.
Benign hereditary chorea
Benign hereditary chorea is a rare, autosomal dominant movement disorder with childhood-onset, non-progressive chorea caused by NKX2-1 mutations, sometimes accompanied by lung and thyroid problems.
Benign lipomatous neoplasm
Benign lipomatous neoplasm (ICD-11 2E80): benign adipose-tissue tumours, chiefly lipoma (2E80.0) and lipoblastoma (2E80.1); lipomas affect about 1% of people and are distinguished from liposarcoma by MDM2 testing.
Benign lymphoepithelial lesion of lacrimal gland
Benign lymphoepithelial lesion of the lacrimal gland (BLEL, Mikulicz disease, ICD-11 9A10.2) is a rare IgG4-related inflammatory lesion causing painless bilateral lacrimal and salivary gland swelling.
Benign neoplasm of choroid
Benign neoplasm of choroid (ICD-11 2F36.0), chiefly the choroidal nevus, a common benign melanocytic eye tumor in about 5% of U.S. adults, with a low 1-in-8845 annual risk of transformation into choroidal melanoma.
Benign neoplasm of cranial nerves
Benign neoplasm of cranial nerves (ICD-11 2A02.3), mostly schwannomas of Schwann-cell origin; vestibular schwannoma is the commonest, managed by observation, radiosurgery, radiotherapy, or surgery.
Benign neoplasm of duodenum
Benign neoplasm of duodenum (ICD-11 2E92.2; ICD-10 D13.2): noncancerous duodenal tumors, mainly adenomas, lipomas, leiomyomas, and Brunner gland lesions; 10–20% of duodenal tumors, managed by endoscopic resection.
Benign neoplasm of endocrine glands
Benign neoplasm of endocrine glands: non-cancerous tumors of hormone-producing glands, ICD-11 code 2F37 (ICD-10-CM D35). Includes pituitary, parathyroid, and adrenal adenomas; excludes endocrine pancreas, ovary, testis, hypothalamus.
Benign neoplasm of hypopharynx
Benign neoplasm of hypopharynx (ICD-11 2E90.7, ICD-10 D10.7): non-cancerous tumors of the lower throat, including lymphoepithelial cysts, papillomas, lipomas, fibrovascular polyps, schwannoma, and granular cell tumor, treated by endoscopic or open excision.
Benign neoplasm of lip
Benign neoplasm of lip (ICD-11 2E90.0; ICD-10 D10.0), a non-malignant lip growth without invasion or metastatic potential; includes pleomorphic adenoma, lipoma, fibroma, and vascular lesions, 3.3% of labial biopsies.
Benign neoplasm of nasopharynx
Benign neoplasm of nasopharynx (ICD-11 2E90.6), also called benign tumour of epipharynx or postnasal space: a non-metastasizing nasopharyngeal growth, most often juvenile nasopharyngeal angiofibroma in adolescent males, treated surgically.
Benign neoplasm of ovary
Benign neoplasm of ovary (ICD-11 2F32) is a noncancerous ovarian tumor such as cystadenoma, dermoid cyst, endometrioma, or fibroma (2F32.1); ultrasound O-RADS stratifies risk and laparoscopy is standard surgery.
Benign neoplasm of spinal cord
Benign neoplasm of spinal cord (ICD-11 2A02.4; ICD-10 D33.4): a noncancerous spinal cord tumor, usually schwannoma, meningioma, ependymoma, or hemangioblastoma, treated by microsurgical resection or radiosurgery.
Benign neoplasm of stomach
Benign neoplasm of stomach (ICD-11 2E92.1): non-cancerous gastric growths, mainly gastric polyps (fundic gland, hyperplastic, adenoma) and subepithelial lesions (leiomyoma, lipoma, schwannoma, ectopic pancreas), diagnosed by endoscopy and EUS.
Benign neoplasm of the nipple
Benign neoplasm of the nipple (ICD-11 2F30.7): non-metastasizing nipple tumors without malignant features, mainly nipple adenoma (erosive adenomatosis) and intraductal papilloma, which can mimic Paget disease and need biopsy.
Benign neoplasm of tongue
Benign neoplasm of tongue (ICD-11 2E90.1): non-malignant tongue tumors including squamous papilloma, hemangioma, schwannoma, lipoma, and granular cell tumor; well-circumscribed submucosal masses, resected transorally, recurrence about 15% at tongue base.